I think you are not getting the needle into the cavernosa. Suggest you go back to the uro and have him/her watch you inject so they can let you know.
I have injected roughly 375 times over 2.5 years. Only missed once....only failed to get erection that same time. i use alprostadil.

have injected approximately 375 times over 2.5 years. ...see below for rest of my reply.

Have been injecting for 2 1/2 years, roughly 3 times per most weeks...probably 75% of weeks it's 3. Three times a week has been my uro's guidance. and she also says I should wait 24 hours minimum between injections. I have gone over the limit on occassion with no ill effects.

Do go for the full disclosure. I think we all face this. I am often asked about my ED injectable medication by medical professionals from nurses to doctors....yes, including my new dermatologist, another young, new female doctor. I used to sometimes withhold the information when it just didn't seem ...

In my case I do not have an implant (I use injections, with almost 100% success in getting hard, durable erections) but I have almost the exact same problem as you describe. And while I am unable to climax often, it is not always. And just when it seems to be getting better, it gets worse. When I do...

I have had similar issues , using Edex (Alprostadil) for over 2 1/2 years. it first started to be a problem about 3 months in. It does, pardon the pun, 'come and go". Example: the last three times I had sex with my wife I came. This was over a 2 week span. The first 2 orgasms were incredible, r...

Different guys prefer different cock rings. I've tried a few and find those cheap silicone ones they sell in sex shops to be the most effective. They are tight enough but not too tight as to cause pain. One of the 2 I have can quite easily be slipped over my balls and the base of my penis at the sam...

I have been instructed by my urologist not to use a cock ring with injections. So i'd check with yours before you try it again. Not sure what med you are injecting , but 35 units sounds like a very large dose. My doctor started me (ini office) with 8 units. I got an erection but wanted more and I we...

All of the guys who have replied hit on good points. you should take what they say into account. The certainty of the erection does make up for any loss in spontaneity , by far! I set up my syringe in advance of any foreplay, except maybe verbal. The we start with heavier foreplay, which almost alwa...

My uro in an examination room. I was happy that it was her because I'd been very open about my ED issues with her, and besides she was an attractive youngish woman. She didn't give a lot of instruction but gave me a flier with information, including diagrams and a link to a video that I could use at...