Erectile dysfunction from the fastsize

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prematuredysfunction
Posts: 7
Joined: Wed Mar 07, 2012 12:02 am

Erectile dysfunction from the fastsize

Postby prematuredysfunction » Thu Mar 08, 2012 9:08 pm

Here is my story

I am a 32 year-old male. At the age of 28, and to my eternal regret, I used a penile traction device x 8 months (~800 hours total) in an attempt to correct an asymptomatic ~15 degree congenital penile curvature/indentation after reading about it's use for Peyronie's disease in the literature. Prior to this, my IIEF-5 was consistently 25 (ie. no erectile problems whatsoever). I was not sexually active from 27.5yo to 29.9yo during busy grad school. Upon resuming sexual relations at 30, I experienced persistent moderate-to-severe ED characterized by tumescence but not rigidity or momentary rigidity followed by rapid detemuscence. I have also noticed a complete lack of spontaneous or nocturnal erections unless I am on pde-5 inhibitors. My IIEF-5 is now roughly 12. I initially attributed my ED to psychogenic ED and self-treated with pde-5 inhibitors but have come to realize recently that this is definitely not purely psychogenic. PDE-5 inhibitors work ~90% of the time with normal rigidity, but even with pde-5i I tend to detumenesce rapidly without persistent manual or coital stimulation. I am completely dependent on PDE-5 inhibitors for intercourse.

There are multiple possible mechanisms of injury from stretching - the most concerning of which is nerve damage, as this is largely not treatable except in the month to year period after injury. Stretch injury is also of a chronic nature since most people are stretching several times a week to daily, and there are no good models (eg. rat) for chronic injury in the literature. The penis is the one organ in the body which you can stretch, but there is no significant resistance from bone as in other body appendages. There really is no protection for your nerves when you are stretching your penis. Nerve stretch is one of the contributing factors to erectile dysfunction during prostatectomy.

Vascular damage is also a risk:
From http://www.the-european-institute-ugrs. ... =text#text

Patients who have used such devices have often reported that either during, or shortly after, applying them they suffered markedly impaired erections. In fact, Doppler sonography tests on them later revealed extended AA and AV shunts – in other words, bridging between blood-vessels that alter the blood-flow. Such shunts occur quite frequently and are generally congenital. However, due to long-term use of these stretching devices, which constantly compress the penile distal vessels, it would seem the shunts become distended, resulting in a permanent change in the blood-flow.

padreest
Posts: 103
Joined: Sat May 21, 2011 4:15 pm

Re: Erectile dysfunction from the fastsize

Postby padreest » Fri Mar 09, 2012 11:34 am

what is PDE5?

bob1138
Posts: 449
Joined: Wed Sep 28, 2011 6:41 pm

Re: Erectile dysfunction from the fastsize

Postby bob1138 » Sat Mar 10, 2012 2:00 am

Padreest,

A phosphodiesterase type 5 inhibitor, often shortened to PDE5 inhibitor, is a drug used to block the degradative action of phosphodiesterase type 5 on cyclic GMP in the smooth muscle cells lining the blood vessels supplying the corpus cavernosum of the penis. These drugs are used in the treatment of erectile dysfunction, and were the first effective oral treatment available for the condition. Because PDE5 is also present in the arterial wall smooth muscle within the lungs, PDE5 inhibitors have also been explored for the treatment of pulmonary hypertension, a disease in which blood vessels in the lungs become overloaded with fluid, usually as a result of failure of the left ventricle of the heart.

Hope this is of some help.

Bob

Frank Talk Admin
Site Admin
Posts: 665
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Location: NYC

Re: Erectile dysfunction from the fastsize

Postby Frank Talk Admin » Sat Mar 10, 2012 6:38 am

PDE5 = viagra, levitra, cialis

Peckerwood
Posts: 218
Joined: Tue Aug 23, 2011 10:48 am
Location: Woodypecker41@gmail.com

Re: Erectile dysfunction from the fastsize

Postby Peckerwood » Sat Mar 10, 2012 4:27 pm

Since most of us don't speak medicalese, it's nice to have an interpreter, Paul. Should one say to one's wife or girlfriend, "My libido is suggesting the need for coital exploration this evening; however, please desist your aggressive behavior until I have ingested my PDE5 inhibitor [one or two hours prior to coitus] to counteract "the degredative action of phosphodiesterase type 5 on cyclic GMP in the smooth muscle cells lining the blood vessels supplying the corpus cavernosum of [my] penis"?

antelope
Posts: 1497
Joined: Sun Nov 14, 2010 3:17 am
Location: Baton Rouge

Re: Erectile dysfunction from the fastsize

Postby antelope » Sat Mar 10, 2012 5:31 pm

Eschew obfuscation.

G
BR
Born 1948, wed 1969. BPH & Type II Diabetes at age 35. TURP-2002; ED even before that--diabetes. Cardiac valve surgery: 2007 & 2019. Poor results with pills. Started trimix injections in Nov, 2010. Great results from the very beginning.

bob1138
Posts: 449
Joined: Wed Sep 28, 2011 6:41 pm

Re: Erectile dysfunction from the fastsize

Postby bob1138 » Sun Mar 11, 2012 3:30 am

Just to clarify.

PDE 5 = Phosphodiesterase Type 5

PDE 5 INHIBITOR = Viagra, Cialis, Levitra

Bob

Peckerwood
Posts: 218
Joined: Tue Aug 23, 2011 10:48 am
Location: Woodypecker41@gmail.com

Re: Erectile dysfunction from the fastsize

Postby Peckerwood » Sun Mar 11, 2012 10:02 am

Since our intent is to communicate clearly, rather than obfuscate, it seems that plain English would work best in Frank Talk. Anglo-Saxon rather than Latin roots get to the heart of the matter when talking about sex. Just think of the rich, imitative sounds of those familiar Anglo-Saxon words.
John

prematuredysfunction
Posts: 7
Joined: Wed Mar 07, 2012 12:02 am

Re: Erectile dysfunction from the fastsize

Postby prematuredysfunction » Sun Mar 11, 2012 11:52 pm

sorry! i cut and pasted from an email i sent to a urologist.

TwoStep
Posts: 222
Joined: Sat Mar 24, 2012 1:22 pm

Re: Erectile dysfunction from the fastsize

Postby TwoStep » Tue Mar 27, 2012 2:06 am

I'm sorry you find it so hard to read premature's post. But at least it's been helpful to me. I'm in a similar situation and I just had cavernosal nerve damage diagnosed on an EMG scan. I hope we can keep in touch, premature. I'm considering an implant myself.


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