Paroxetine vs Sertraline

One out of Three men in America suffer with PE. It's the largest sexual dysfunction there is. Since there is no discussion board dedicated to PE so far, we will try to fill the need here!
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mod123
Posts: 10
Joined: Fri Aug 14, 2020 8:30 am

Paroxetine vs Sertraline

Postby mod123 » Sat Jan 22, 2022 3:28 pm

Hi, anyone has any experience with Paroxetine vs Sertraline for lifelong PE? I am currently on Paroxetine but am suffering from severe tiredness and dry mouth and am thinking of switching to Sertraline. Any advice or information on your personal experience would be greatly appreciated.
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bionicbrother
Posts: 335
Joined: Thu Oct 22, 2020 1:53 am
Location: San Francisco bay area

Re: Paroxetine vs Sertraline

Postby bionicbrother » Tue Sep 20, 2022 6:33 pm

I use Paroxetine and it works and yes it does have some side effects- for me it makes me bit dull and dizzy. I am sure Sertraline would have similar side effects..
40 yrs old. Have ED and PE all my life. Never had penetrative sex all my life. Tried almost all kinds of options( pills, injections, natural therapies etc. Turned Bionic on May 17'22 with Titan by Dr.Karpman infrapubic approach.16cm+2 RTE
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tonyareias
Posts: 100
Joined: Tue Jan 04, 2022 10:26 pm

Re: Paroxetine vs Sertraline

Postby tonyareias » Tue Sep 20, 2022 11:27 pm

Paroxetine is more sedative, specially in first weeks. Wait more weeks. Also low dosing (2.5/5/10mg) works for PE and don’t make you too sleepy.

Sertraline is more active (dopaminergic), but in general the same effects.

1 - If you are starting, wait some weeks
2 - Try low dosing
3 - Switch to other SSRI
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BearsWin
Posts: 51
Joined: Thu May 12, 2022 11:37 pm

Re: Paroxetine vs Sertraline

Postby BearsWin » Sat Feb 25, 2023 8:31 pm

I do paxil on nights before sex is a likelihood, around 20mg. If I do just one night I feel fine after - if I do multiple nights in a row I start to be way tired. My ex wife took it for extreme anxiety/OCD - 40mg daily - she napped for hours daily.
Born 1966. PDE-5s since age 40. Decreasing efficacy age 50. Started on Trimix 2022 - variable response even at high doses. Coloplast Titan 11/1/22 Dr. Yafi UCI, submuscular/ectopic reservoir. History of hypertension. Married, Nevada.
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