Antidepressants and ED

Anything goes when it comes to ED.
Flavio
Posts: 907
Joined: Wed May 19, 2010 4:56 am

Antidepressants and ED

Postby Flavio » Wed Feb 10, 2021 3:05 pm

The brain really is your #1 sex organ and altering brain chemistry will have a great impact on your sexual health.

Several centrally acting drugs have been proposed for the treatment of ED but I've had very little luck with these meds: apomorphine, cabergoline, trazodone. Apomorphine on its own improved my erection but side effects were unbearable when I combined it with other treatments (I almost passed out!), so I had to quit.

This is where antidepressants come in. SSRIs may hurt your sex life (remember Tony Soprano!) but not all antidepressants are erection killers and, in theory, some may even improve sexual function.

I've always suffered from OCD and, at least according to this study, mirtazapine may be a God's send:

Mirtazapine is an atypical antidepressant with a2 adrenergic antagonist and serotonin 5‐HT2 and 5‐HT3 receptor‐blocking activity. In theory, it should not worsen and perhaps may improve sexual function.

https://onlinelibrary.wiley.com/doi/abs/10.1002/(SICI)1520-6394(1999)9:4%3C175::AID-DA5%3E3.0.CO;2-0

Why do some antidepressants worsen sexual function and others improve it?

What is your personal experience with antidepressants? Were there any that you'd like to recommend?
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Flavio
Posts: 907
Joined: Wed May 19, 2010 4:56 am

Re: Antidepressants and ED

Postby Flavio » Fri Feb 12, 2021 2:47 pm

I am doing some reading on antidepressants and the list of side effects is scary.

Buproprion (Wellbutrin) may not cause ED but it is clearly a dangerous drug:

https://meduza.io/en/news/2020/02/18/ru ... n-the-mail
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.


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