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Comparison bewtween seven PDE-5 inhibitors

Posted: Sat Nov 28, 2020 9:00 am
by Flavio
An article that compares all seven existing PDE-5 inhibitors for the treatment of erectile dysfunction (sildenafil, vardenafil, lodenafil, udenafil, tadalafil, avanafil and mirodenafil):

https://www.mcmasteroptimalaging.org/fu ... s-side-276

I'm currently using avanafil but I'm planning to try daily Cialis 5mg to improve vasculogenic health.

If you have already tried some or all of these medications, please tell us which one you prefer and why.

Re: Comparison bewtween seven PDE-5 inhibitors

Posted: Sun Nov 29, 2020 6:16 am
by Flavio
An excellent article on how to improve the efficacy of PDE-5 inhibitors:

https://www.nature.com/articles/3901215

They mention the combination PDE-5 inhibitors + oral phentolamine, a combination that I have used for years with excellent results.

Re: Comparison bewtween seven PDE-5 inhibitors

Posted: Mon Nov 30, 2020 11:33 am
by Tellmehow
Flavio wrote:An article that compares all seven existing PDE-5 inhibitors for the treatment of erectile dysfunction (sildenafil, vardenafil, lodenafil, udenafil, tadalafil, avanafil and mirodenafil):

https://www.mcmasteroptimalaging.org/fu ... s-side-276

I'm currently using avanafil but I'm planning to try daily Cialis 5mg to improve vasculogenic health.

If you have already tried some or all of these medications, please tell us which one you prefer and why.


Thanks indeed Flavio. When they say for example the highest percentage of efficiency of Sildenafil is 59%, it means 59% of men see improvement in their erectile function or each individual sees maximum 59% improvement in his erectile function? If the second one is correct I'm wondering how they can calculate the percentage?

Re: Comparison bewtween seven PDE-5 inhibitors

Posted: Mon Nov 30, 2020 4:14 pm
by Flavio
Tellmehow wrote:[...] Thanks indeed Flavio. When they say for example the highest percentage of efficiency of Sildenafil is 59%, it means 59% of men see improvement in their erectile function or each individual sees maximum 59% improvement in his erectile function? If the second one is correct I'm wondering how they can calculate the percentage?


I believe it's 59% of men.

Udenafil (brand name Zudena) seems to be an extremely interesting drug. Quick to act (less than 1 hour!) and the effects last for 10+ hours, which allows for great spontaneity.

The problem is udenafil is not yet FDA-approved and some of the online pharmacies that sell it seem a bit shady.

I have contacted Dong-A Pharm, the manufacturers of udenafil in South Korea, and asked them about reliable international retailers, let's see if they can help.

If anyone knows where to get udenafil, please send me a PM.

Re: Comparison bewtween seven PDE-5 inhibitors

Posted: Mon Nov 30, 2020 5:00 pm
by Flavio
An excellent 5 min. video on udenafil, everything you need to know about this ED treatment:

https://www.youtube.com/watch?v=cZTptaM8XG8

Re: Comparison bewtween seven PDE-5 inhibitors

Posted: Mon Nov 30, 2020 5:56 pm
by Flavio
According to this Reuters article, Viagra is still the most effective of the lot but has the worst side effects:

https://www.reuters.com/article/us-ed-d ... TT20150407