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Question to people who take tadalafilo for DE. I have eaten two apples 40minutes before I ate my dose of tadalafilo. There are any problem with that like less effect?

I mean if the effect is going to be minor because I ate apples before?

Tadalafil will not usually be affected by that amount of food. Of course everyone is different, but in general, Tadalfil (Cialis), Avanfil (Stendra) will not be negatively affected by the presence of food in your stomach. Sildenafil (Viagra) must be on an empty stomach to be most effective.
Now the caveats - after a big meal, there is likely going to be some lowered response. But the fact is Tadalafil is not meant to be a fast acting drug. Ideally it needs 2 hours to reach peak levels in blood. A lot of Food will slow it down. If you want to have sex in the evening, take the meds late afternoon. Some guys report that Cialis actually works better the next morning than it does that night. It is really important if you are starting with these drugs that you take them on your own at first so you can judge how effective they are without the stress of a partner involved.
If you need a fast acting drug, use Stendra. It tends to work in less than 30 minutes.
Paul