Flame885 wrote: He ran full horome tests and found the total testosterone to be 311, all other hormones where within normal range. He told me that this is within normal range but based on my age and size , this is considered low. He prescribed clomid 25 mg daily for 3 months.
You have had some great replies.
Your T level seems to be an issue here and may or may not be the direct or indirect cause of your ED.
I have only one thing to add seeing as you may be about to embark on the long journey of HRT: Do some research yourself on Enclomiphene citrate. It is the better, safer form of Clomiphene citrate (Clomid) for use in males. Your doctor has put you on Clomid to try and improve and maintain natural testosterone production and also keep all the “upstream” hormones (LH, FSH and GNRH) in place as well. This is always preferable to a life on TRT. I suspect he is considering doing this for the short term and then slowly stopping the therapy, hoping the higher T level will stick. Sometimes this does not work.
Clomiphene citrate (Clomid) is made up of two parts: Enclomiphene and Zuclomiphene.
Sexual function can be all over the place when on testosterone replacement in young men. It may do nothing to help your erectile function as it causes the shutdown of other hormones that contribute to the whole process of sexual function. This in itself can cause issues with erectile function.
Enclomiphene citrate is the single isomer version of Clomid. Clomid can cause many side effects in men, hence why it is not good to use for long periods and it can also make erectile function worse due to the estrogenic like effects it can also cause. This can inhibit erectile function in some men, not all. Which is predominately caused by the “Zuclomiphene” part in Clomid. Excessive estrogen receptor agonism (stimulation) is not desirable for good sexual function in the male.
There are compounding pharmacy’s in the US that are now making Enclomiphene citrate, so it is possible to get the drug. It has a long history with a company called Repros Therapeutics of whom tried to get it passed as Androxal.
It will only work if you have secondary hypogonadism, in cases where the pituitary needs a little nudge to produce higher levels or LH and FSH, typically in cases where T levels are borderline low like yours. In some men this may need to be long-term therapy as their pituitary will simply revert back to the lower level when the drug is stopped. When this happens with Clomid, the doctor usually puts you on T replacement. Enclomiphene (Androxal) could have been the solution for this, as it is better to use on a permanent basis for the reasons of fewer side effects and that sexual function actually works much better for a higher percentile of men whilst they are actually taking the drug.
Here is one pharmacy I found that is compounding it in the US:
https://tailormadecompounding.com/https://imcwc.com/wp-content/uploads/20 ... atalog.pdfDefy medical also appear to have access to it:
https://www.defymedical.com/If I was able to get Enclomiphene in my country being Australia, I would certainly give this a try so that I did not have to be on Testosterone replacement. Unfortunately no one is compounding it here.
The other possible alternative use for this is alongside TRT, to keep the testes functioning and some LH and FSH in the system. Some doctors don’t think you need this to function well sexually. But let me tell you as someone who has experienced this in my own body for many years, T replacement does not work as well as our natural system. This is why experienced doctors will put you on HCG (Pregnyl or Ovidrel) with exogenous testosterone, so as to try and compensate for the loss of upstream hormones (These are the doctors who understand hormone replacement better than the rest.)
LH is an important hormone in the body, shutting it down does have consequences. T replacement for the most part shuts it down.
For older males in their 60’s and 70’s reading this, Enclomiphene citrate used as a solitary form of HRT, may not work, for the simple reason of aging. The testicles have aged and may not be capable of producing a higher amount of T and the pituitary may also not be very responsive. T replacement is the only option for this age group and often yields a satisfactory result especially when combined with the IC injections such as Trimix (testosterone rarely does anything to improve erectile function in older men, mainly libido).
If it were me, I would try the above and if need be IC penis injections (for persistent ED) before considering an implant. Nothing beats what we were born with, even if an injection is needed to give a helping hand. As you are in a relationship with someone this can worked out so as to not be an issue with your sex life and the result may actually surprise you as has been mentioned by many others.
If you need more information about HRT and my experience with it (over 20 years) don’t hesitate to ask.