Intrapenile drug delivery system
Posted: Tue Feb 15, 2022 8:07 pm
This orphan product works by the same principle as intracavernosal injection, but it uses a permanent catheter into a corpus cavernosum so one doesn’t need to insert a needle into the corpora for each erection.
https://journals.sagepub.com/doi/abs/10 ... lCode=stda
Downsides: reservoir (outside the penis) needs to be filled by injection which could lead to infection. Catheter could irritate the corporal tissue.
Benefits: The implant is less invasive and potentially less morbid than an inflatable or rod prosthesis, and the erection is more physiological. Convenience is better than with injections. Could potentially be less damaging to the tunica than the frequent needle puncture with intracavernosal injections.
Mentions of such a device:
Clinical experiments
https://onlinelibrary.wiley.com/doi/abs ... .tb01711.x
https://journals.sagepub.com/doi/abs/10 ... lCode=stda
https://pubmed.ncbi.nlm.nih.gov/9224341/ (no reservoir)
https://pubmed.ncbi.nlm.nih.gov/3676676/ (no reservoir)
Animal experiment
https://pubmed.ncbi.nlm.nih.gov/2288047/ (no reservoir)
Reviews, biographical, etc.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891291/
https://www.tandfonline.com/doi/full/10 ... 014.925085
http://research.vuse.vanderbilt.edu/srd ... p12/fp.pdf (school project)
https://journals.sagepub.com/doi/abs/10 ... lCode=stda
Downsides: reservoir (outside the penis) needs to be filled by injection which could lead to infection. Catheter could irritate the corporal tissue.
Benefits: The implant is less invasive and potentially less morbid than an inflatable or rod prosthesis, and the erection is more physiological. Convenience is better than with injections. Could potentially be less damaging to the tunica than the frequent needle puncture with intracavernosal injections.
Mentions of such a device:
Clinical experiments
https://onlinelibrary.wiley.com/doi/abs ... .tb01711.x
https://journals.sagepub.com/doi/abs/10 ... lCode=stda
https://pubmed.ncbi.nlm.nih.gov/9224341/ (no reservoir)
https://pubmed.ncbi.nlm.nih.gov/3676676/ (no reservoir)
Animal experiment
https://pubmed.ncbi.nlm.nih.gov/2288047/ (no reservoir)
Reviews, biographical, etc.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891291/
https://www.tandfonline.com/doi/full/10 ... 014.925085
http://research.vuse.vanderbilt.edu/srd ... p12/fp.pdf (school project)