Is the New ED Drug Vitaros Any Good?

[alterr]

There is a drug in Canada called Vitaros for ED. Has anyone taken it? Is it good?

[Neisseria]

Vitaros is a topical cream that contains Alprostadil, one of the 3 drugs that are commonly used in the injection therapy. The aim is to create an erection like the ones you get with injections with the benefit of a less invasive aplication. I don´t know its efficacy

[alterr]

Vitaros is a topical cream that contains Alprostadil, one of the 3 drugs that are commonly used in the injection therapy. The aim is to create an erection like the ones you get with injections with the benefit of a less invasive aplication. I don´t know its efficacy

but do you know if its currently being sold at all?

[Flavio]

It seems to be going through the necessary approval procedures in Europe, so maybe it's still too early to buy it:

http://www.apricusbio.com/news/

[mandangalo]

I've looked dilitently at web sites for Stendra and Vitaros information and, as far as when Canada will have it on pharmacy shelves, this site is the one to keep your eye on regardless of some of the funky repetition of Toronto or Ontario, if it's still doing that: http://www.ontariomenshealth.ca/vitaros-for-toronto-men

[Palladio]

I suspect Vitaros will be a commercial failure. PDE5 inhibitors have too many advantages.

PDE5i doesn’t need to be stored in a fridge, where it might be seen by anyone, - it can be discretely kept in your wallet, where it’s readily available.. Viagra works on 75% of men as against (according to the Buvat trial) 25% of men. Viagra improves IEFF-EF score by around 10 points, as against 2.5 for Vitaros. And Viagra much easier to administer. To put the worst light on Vitaros administration: you need to visit the lavatory to make fumbling attempt, probably in poor light, at an age where your close-vision is failing, perhaps after a few drinks, to very carefully apply a drop of liquid to the tip of your penis, and not spill in on the floor or on your trousers. It might almost seem not worth the effort. (And, of course, if you’re not living with your lover, you have to remember to take it out of the fridge and put in in your pocket when you leave home.)

If Viagra works for you you’ll probably have little interest in Vitaros. Where Viagra doesn’t’ work, due to somatic conditions, Vitaros unlikely to overcome those conditions either. (Though Vitaros in combination with PDE5i might offer advantages.)

Vitaros is most likely to be superior to PDE5i in cases of psychogenic dysfunction, in those cases where PDE5i can’t adequately overcome a slow or weak dopamine response. A slow or weak dopamine response is less of an issue with Vitaros, as an erection should automatically or semi-automatically be induced, -which is, of course, more likely to occur where the patient has no organic risk factors. Following that erection, the delayed dopamine response may, after ten or fifteen minutes kick-in, and build on the benefits of Vitaros, to result in good sex. (You might expect, in such cases, a fairly dramatic increase in IIEF-EF score, on a par with the MUSE trials; - but large improvements in EF score seem not to have occurred in even a minority of men in either Vitaros trial. Even the top performers seem to had increases in score of perhaps around 5 or 6.)

It is estimated that at least 80% of ED is organic in origin, and so Vitaros will only appeal to a small minority of dysfunctional men: the minority who seek treatment, the minority of a minority for whom PDE5i doesn’t work, and then a minority of a minority of a minority who’s dysfunction is psychogenic. (Men such as me, who is looking forward to trying it)

[alterr]

I suspect Vitaros will be a commercial failure. PDE5 inhibitors have too many advantages.

PDE5i doesn’t need to be stored in a fridge, where it might be seen by anyone, - it can be discretely kept in your wallet, where it’s readily available.. Viagra works on 75% of men as against (according to the Buvat trial) 25% of men. Viagra improves IEFF-EF score by around 10 points, as against 2.5 for Vitaros. And Viagra much easier to administer. To put the worst light on Vitaros administration: you need to visit the lavatory to make fumbling attempt, probably in poor light, at an age where your close-vision is failing, perhaps after a few drinks, to very carefully apply a drop of liquid to the tip of your penis, and not spill in on the floor or on your trousers. It might almost seem not worth the effort. (And, of course, if you’re not living with your lover, you have to remember to take it out of the fridge and put in in your pocket when you leave home.)

If Viagra works for you you’ll probably have little interest in Vitaros. Where Viagra doesn’t’ work, due to somatic conditions, Vitaros unlikely to overcome those conditions either. (Though Vitaros in combination with PDE5i might offer advantages.)

Vitaros is most likely to be superior to PDE5i in cases of psychogenic dysfunction, in those cases where PDE5i can’t adequately overcome a slow or weak dopamine response. A slow or weak dopamine response is less of an issue with Vitaros, as an erection should automatically or semi-automatically be induced, -which is, of course, more likely to occur where the patient has no organic risk factors. Following that erection, the delayed dopamine response may, after ten or fifteen minutes kick-in, and build on the benefits of Vitaros, to result in good sex. (You might expect, in such cases, a fairly dramatic increase in IIEF-EF score, on a par with the MUSE trials; - but large improvements in EF score seem not to have occurred in even a minority of men in either Vitaros trial. Even the top performers seem to had increases in score of perhaps around 5 or 6.)

It is estimated that at least 80% of ED is organic in origin, and so Vitaros will only appeal to a small minority of dysfunctional men: the minority who seek treatment, the minority of a minority for whom PDE5i doesn’t work, and then a minority of a minority of a minority who’s dysfunction is psychogenic. (Men such as me, who is looking forward to trying it)

You sound like a sokesperson for Pfizer. Why go into a lengthy and unnecessary tirade about it? I hope youre not. Anyway, I hope vitaros comes out soon. It will change people's lives. I know most of us are tired of taking the blue pill and need something safer, faster, and better.

[billylee]

Palladio,
Thanks for post. Personally, I think it is good for many of the points you made to be emphasised. With all the wonderful things one may read and/or observe on television about Viagra and Cialis, the fact you mention about that OTHER 25-30% should be understood by those who try it or have tried it, finding the drug did not work on them like maybe it had for a buddy. I've been there, taken all three (#3 is Levitra). ED is tough on us all who know it and if you live in a relation which is geared more in "spontaneous" moments then you can find ED even more disgusting.
billy

[alterr]

Palladio,
Thanks for post. Personally, I think it is good for many of the points you made to be emphasised. With all the wonderful things one may read and/or observe on television about Viagra and Cialis, the fact you mention about that OTHER 25-30% should be understood by those who try it or have tried it, finding the drug did not work on them like maybe it had for a buddy. I've been there, taken all three (#3 is Levitra). ED is tough on us all who know it and if you live in a relation which is geared more in "spontaneous" moments then you can find ED even more disgusting.
billy

Do you know when Vitaros will come out? It was supposed to come out 3 months ago in November.