why did tri mix stop working

[formsetter]

had ed for about 10 years pills worked pretty good then they stopped

Doc gave me tri mix WOW did it work great for about a year then it started working less every time
I was on T-106 doing 4iu at the end
doc switched me to ST-2 I tried 3iu didn't really work either. All it did was give me a chub and ache like hell

does anyone have any idea what I should try next

I feel like I am out of options. I have a implant consultation in two weeks with Cavell
I feel that this is my only option left

[Old Guy]

Welcome to FT. Pills then injections then implant is the usual course. Sorry.
One thing is the implant will be reliable and work whenever you want. You have picked a good doc from what I've seen in his reviews. Read up and ask all the questions you want of doc, he's heard them all before.

[formsetter]

doc wants me to try quad mix
he wrote me a script today
I guess I will give it a try
has anyone had better luck with that

[Old Guy]

I switched to Quadmix when Trimix quit working. It only worked for me for about 6 months. I was up to 60 units of Trimix with poor results. First injection of 10 units of Quadmix was like my first injection ever, nice erection that lasted for an hour or so. By the third month I needed 40 units, then 50 then it was unreliable by the 7th month.

[Pumpkinman]

Welcome to FT. Pills then injections then implant is the usual course. Sorry.
One thing is the implant will be reliable and work whenever you want. You have picked a good doc from what I've seen in his reviews. Read up and ask all the questions you want of doc, he's heard them all before.

That may be the route for a percentage of people and its not that the pill or injections "Stop" working its because most people don't try to resolve the issues that is causing their ED.

[jimmyd24]

Hi
I went though the same thing.
My uro told me when I started on trimix that I would eventually need an implant.
He was right.
I got my Implant October 2022.

[formsetter]

Jimmy
Did you try quad mix
if so did it work for a while

I know that I will be needing a implant iI was hoping that quad mix would get me through the summer
so I could get surgery in the fall

[bldoink]

had ed for about 10 years pills worked pretty good then they stopped

Doc gave me tri mix WOW did it work great for about a year then it started working less every time
I was on T-106 doing 4iu at the end
doc switched me to ST-2 I tried 3iu didn't really work either. All it did was give me a chub and ache like hell

does anyone have any idea what I should try next

I feel like I am out of options. I have a implant consultation in two weeks with Cavell
I feel that this is my only option left

The T-106 and ST-2 terms are proprietary pharmacy specific terms. They mean nothing to anyone else who doesn't use the same pharmacy. What are the ingredients and amounts on the vial labels. Are they listed as per vial or as per milliliter? As per one milliliter seems to be more standard but there's a lot of variation.

Also, doses in iu or international units doesn't compute. I don't think there could be an international unit standard for bi-mix, tri-mis, quad-mis or etc. That's because they are mixes with varying percentages of individual ingredients. I suppose they could develop an international unit standard for alprostadil mono-mix but I doubt they have.

The penile intracavernosal injections for ED are more commonly described in U-100 insulin units, at least on this forum and secondly as percentages of milliliters. One reason doses are usually given in u-100 insulin units is that's the type of syringes we usually use. If you meant u-100 insulin units then you doses would be tiny. If you meant milliliters than your doses would have been unrealistically huge. If you meant .3ml and .4ml that would make much more sense and equate to 30 and 40 units, as in u-100 insulin units.

The pain or ache could be from sensitivity to the alprostadil. It could also be from improper injection technique where some or part of the dose gets injected into the wrong tissues.

If you have a good injection technique, and I assume you do if they worked well for a year, then I'll assume your ED has worsened to the point that injection may no longer be effective for you. But it's hard to have a good idea on this due to the confusion on your injection mix and dose.

I 'm sorry I don't have more useful information to share. I do wish you the best and pray you find a satisfactory solution to you situation.

[jimmyd24]

I did try Quadmix.
It didn't work much better, and it was painful.
Made my penis ache

[Pumpkinman]

Hi
I went though the same thing.
My uro told me when I started on trimix that I would eventually need an implant.
He was right.
I got my Implant October 2022.

I talked to my Uro about that scenario as he stated that's not necessarily the norm, as he had some patients that use Trimix for 20 to 30 years with positive results but those are the patients that really work to control the underlying causes of their ED and the route cause of their ED IS mainly psychological...