Bimix & antidote dose

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Dent4ever
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Joined: Wed Dec 21, 2022 7:21 pm

Bimix & antidote dose

Postby Dent4ever » Wed Jun 21, 2023 8:44 pm

Hey everyone,

I have a scheduled implant date with Dr hanky for now for the end of July but he was admant I give bimix a shot at home and see how I like it. The units/measurements on the site is all over the place but per the nurses advice, If I solved the entire bottle of bimix with the provided 5ml bag water, then every -of the 10 notches on the 1cc insulin needle would give me one unit worth of the medication. I honestly just used 2.5ml to solve the med so this way im injecting less volume into the corpora. So for the more experienced users on this topic:

1, even 3 units made me ROCK hard but kept going soft during thrusting.. the erection stayed about an hour nd a half afterward is this because im using such a low volume of the medication or is it a possible outflow problem.

2, The phenylephrine antidote. The labels says inject 1ML every 5-10 mins afterward if erection doesnt subside. That's a LOT of volume and I only received a 2ML bottle of it. A LOT of memebers also just suggested sudaphed or Walphed as you dont have to inject and it works just as well.

3, I went for it because, what do I have to loose, the implant is going to be there but a lot of people did mention dont skip the fun/efficacy of the bimix for however long it works for you. Once I need to step it up to try mix I will probably get implanted because further scar tissue (which I already have albeit mildly) will just cause more problems.

4, and finally, did anyone regret hassling w injections -cause to me its a freaking hassle as Im a single guy, can't go to sleep right after sex etc.. and just went straight for the implant? I won't give up my reserved spot but I dont have much time "field testing" this so to say

Any and all advice would be dearly appreciated. Im usually very good at measurements etc.. but the nurses were all over the place with starting dose/how much to inject etc
42 M. Mild peyronies like symptoms for well over a decade. Mostly related to PFS syndrome I believe. Seriously considering an Implant. Trying to mentally accept the situation, Pills barely work and trimix gel doesn't work, tried injections -hated it.

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bldoink
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Re: Bimix & antidote dose

Postby bldoink » Wed Jun 21, 2023 10:59 pm

Dent4ever wrote:Hey everyone,

I have a scheduled implant date with Dr hanky for now for the end of July but he was admant I give bimix a shot at home and see how I like it. The units/measurements on the site is all over the place but per the nurses advice, If I solved the entire bottle of bimix with the provided 5ml bag water, then every -of the 10 notches on the 1cc insulin needle would give me one unit worth of the medication. I honestly just used 2.5ml to solve the med so this way im injecting less volume into the corpora. So for the more experienced users on this topic:

That didn't make total sense. I'll start with suggesting you add some novelty/sex shop cock rings to the mix. See the cock ring thread in the Members Only sub-forum.
Why were you started on bi-mix? Was alprostadil mono-mix considered? Why not?
What mg of each component is in the un-reconstituted powder?
If you have a 1cc syringe with just 10 marks on the side, if they are u-100 insulin syringes, then each mark is 10 units.
I agree, sometimes a stronger mix can make the injection process easier and better. However you may want to inject the drugs a little slower to avoid possible pain.
Dent4ever wrote:1, even 3 units made me ROCK hard but kept going soft during thrusting.. the erection stayed about an hour nd a half afterward is this because im using such a low volume of the medication or is it a possible outflow problem.

Each of the drugs used in mono-mix, bi-mix, tri-mix and even quad-mix and penta-mix all have different properties. While I use alprostadil mono-mix, that is the advantage of the muli-mixes. They have the ability to adjust the different drugs in the mix to target the properties you need. So yes, you may need a larger dose of your mix. Or you could just need a different mix.
Yes you could have an outflow problem. Only proper testing can confirm this. The novelty/sex shop can help with this if the outflow isn't too extreme.

Dent4ever wrote:2, The phenylephrine antidote. The labels says inject 1ML every 5-10 mins afterward if erection doesnt subside. That's a LOT of volume and I only received a 2ML bottle of it. A LOT of memebers also just suggested sudaphed or Walphed as you dont have to inject and it works just as well.

I have no experience with the phenylephrine antidote. It's not something I'd want to use unless I was bone hard at 4 hours. The Sudafed or the generics may help and would be the first step I'd take if I was concerned about a priapism. But be sure you get the version that is not the time release and is the pseudoephedrine version. They do make versions under the Sudafed brand that don't contain pseudoephedrine. The stuff you want is usually kept behind the counter and you'll have to ask for it. The reason for that is that it can be a precursor for producing meth.

Dent4ever wrote:3, I went for it because, what do I have to loose, the implant is going to be there but a lot of people did mention dont skip the fun/efficacy of the bimix for however long it works for you. Once I need to step it up to try mix I will probably get implanted because further scar tissue (which I already have albeit mildly) will just cause more problems.

I don't understand this. With the tri-mix you're probably getting less of the drug that is most likely to cause scaring and fibrosis as compared to the bi-mix. Unless your bi-mix is not the common bi-mix ingredients. The alprostadil mono-mix is generally considered to be the least risk for scaring and fibrosis. None are risk free.

Dent4ever wrote:4, and finally, did anyone regret hassling w injections -cause to me its a freaking hassle as Im a single guy, can't go to sleep right after sex etc.. and just went straight for the implant? I won't give up my reserved spot but I dont have much time "field testing" this so to say

Yeah, some guys skip injections.
Once you learn injections and your bodies reaction you can probably go to sleep after sex without worry. I do if I so desire.

Dent4ever wrote:Any and all advice would be dearly appreciated. Im usually very good at measurements etc.. but the nurses were all over the place with starting dose/how much to inject etc

I wish I could be more help but you have me confused on your mix, measurements, and directions.

Good luck.
R.R.P 2011 Mayo Jacksonville, Dr. M. Wehle. Not nerve sparing. C in margins. Radiation 2023, V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ 8 - 14 units. Originally Edex20, then compounded PGE due to cost. Inject. 12 yrs. It works. Treasure coast of FL.

Dent4ever
Posts: 48
Joined: Wed Dec 21, 2022 7:21 pm

Re: Bimix & antidote dose

Postby Dent4ever » Thu Jun 22, 2023 5:28 am

Hey Bidoink and thanks for the ultra detailed reply.

1, A cockring is kind of something I really wanted too avoid, I just hate them and so does my gf's -all so far.
-why was I started on bimix, I have no idea. This was Dr hakes advice to start with as they're less painful than trimix but alprosdatil or a mono-mix was never suggested to me.. would you suggest I try this as the first line? As for the Bimix it's 150mg/5mg per unconstituted vial. According to the nurse was that if I dissolved this in the 5ml backwater that came with it, then id get a total of 50 units. This unit thing kind of confuses me to be honest but I figured this means 2 units on the #2 mark on a 1cc insulin syringe. SO say if I used like 5 units per session, this will allow me to have sex 10 times.

2, id really like to try the mono mix, seems like its been working well for you and to be honest, before the bi, tri & quad mix, Ive never even heard of the mono mix before. And thanks a ton for the Sudafed recommendation. I MUCH rather take this than the antidote which strangely suggests to inject 1 full ML every 5-10 mins until erection subsides and I only got 2ML's of this. Seems like an awful lot of volume and I only get two shots.

3, as you can see in my signature I already have slight hourglass and some scar tissue and I understand no shots are risk-free, but if I can avoid surgery and get this medication to work/get used to it, I rather get a few more years out of it.

ANde lastly, going straight for the implant seems very ideal since Im single and this stuff is a hassle and one of my biggest worries was going to sleep after sex and risking priapism which is why Im increasing my units very carefully. First try I did a small amount of 3 units got me very solid but during thrusting went soft, perhaps the mono mix or higher amount will help in this department.

Again thanks so much for the quick reply
42 M. Mild peyronies like symptoms for well over a decade. Mostly related to PFS syndrome I believe. Seriously considering an Implant. Trying to mentally accept the situation, Pills barely work and trimix gel doesn't work, tried injections -hated it.

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bldoink
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Re: Bimix & antidote dose

Postby bldoink » Thu Jun 22, 2023 10:52 am

Dent4ever wrote:Hey Bidoink and thanks for the ultra detailed reply.

1, A cockring is kind of something I really wanted too avoid, I just hate them and so does my gf's -all so far.
-why was I started on bimix, I have no idea. This was Dr hakes advice to start with as they're less painful than trimix but alprosdatil or a mono-mix was never suggested to me.. would you suggest I try this as the first line? As for the Bimix it's 150mg/5mg per unconstituted vial. According to the nurse was that if I dissolved this in the 5ml backwater that came with it, then id get a total of 50 units. This unit thing kind of confuses me to be honest but I figured this means 2 units on the #2 mark on a 1cc insulin syringe. SO say if I used like 5 units per session, this will allow me to have sex 10 times.

A novelty/sex shop cockring can sometimes provide that extra little boost that can make a big difference. But you will likely have to experiment and waste a few until you find the one(s) that work well for you. There's a pretty big difference between a medical grade constriction ring used with a VED and a novelty/sex shop cock ring. I can't imagine why your girls don't like them. My wife likes them. The ones we use don't get in the way or cause any bother.

The third ingredient of tri-mix is the alprostadil. It's also usually considered the heavy hitter of the mix. It may be the ingredient least likely to cause scaring and fibrosis. I believe it's still the only injection drug approved by the FDA in the proprietary form of the brands of Edex and Caverject.

Some guys can't tolerate alprostadil at all. It causes them too much ache or pain. Some guys have some ache or pain when first using it but find that with continued use they slowly stop getting that ache or pain response. I'm one of those guys. I no longer get any ache from it but did initially. Some guys never have any issues with it. It is my understanding that the majority of guys tolerate alprostadil very well as a mono-mix or as a component of tri-mix. However a substantial minority do have issues with it. I suspect your doctor has had enough guys with issues with alprostadil that he just doesn't want to bother with it.

I'm sharing my experience. I'm not going to tell your doctor how to do his job. I'm not remotely qualified to give medical advice.

You still didn't say what drugs are in your bi-mix. I'm going to assume it's Papaverine 150mg and Phentolamine 5mg. That, dissolved in 5ml of water, makes a 5ml mix of 30mg\1mg per ml. As there are 100 U-100 insulin units per ml by volume, that gives you 500 units, by volume, of your mix. Of course you said you only used 1/2 of the water. So that should have given you a 250 unit (2.5ml) mix of 15mg\0.5mg per ml 60mg\2mg per ml. I think you mis heard the nurse on the 50 unit thing. If you're actually using just 5 units of your 2.5ml/250 unit mix then 5 into 250 should give you the number of doses. 50 doses? I'm going to guess you're reading your syringe marks incorrectly.

I'm going to assume you're using U-100 insulin syringes. I don't know if there is an absolute standard for how many marks are on the U-100 syringes for the different capacity syringes. I have syringe sizes of 0.3cc/ml (30 U-100 units) and 0.5cc/ml (50 U-100 units) and 1cc/ml (100 U-100 units). The 0.3cc syringes have large marks with numbers every 5 units and smaller marks every 1/2 of a unit. The 0.5cc syringes have marks with numbers every 5 units and smaller marks for every unit. The 1cc syringes have marks with numbers every 10 units and smaller marks for every 2 units. You said you're using 1cc U-100 insulin syringes. So you should get my confusion on the number of units you're injecting. If there are 100 marks on your 1cc syringe then 1 mark is 1 unit, I assume. If like my 1cc syringes, the smallest marks are every 2 units.

Dent4ever wrote:2, I'd really like to try the mono mix, seems like its been working well for you and to be honest, before the bi, tri & quad mix, I've never even heard of the mono mix before. And thanks a ton for the Sudafed recommendation. I MUCH rather take this than the antidote which strangely suggests to inject 1 full ML every 5-10 mins until erection subsides and I only got 2ML's of this. Seems like an awful lot of volume and I only get two shots.

Many doctors and compounding pharmacies pass over the mono-mix for some reason. It is probably prescribed most often as the proprietary brands of Edex and Caverject. Those come in proprietary cartridges that mix dry and wet in the cartridge before each use. Very expensive if not covered by insurance. I get my mono-mix compounded from a local compounding pharmacy at the same price they sell the bi-mix or tri-mix.

I don't recall the recommended dose for Sudafed for this purpose. There may be some contra indications if you have blood pressure issues. Ask your doctor first.

Dent4ever wrote:3, as you can see in my signature I already have slight hourglass and some scar tissue and I understand no shots are risk-free, but if I can avoid surgery and get this medication to work/get used to it, I rather get a few more years out of it.

This makes me question the bi-mix. But what do I know. I'm not remotely a medical professional of any kind. I'm just a bubba posting on the internet.

Dent4ever wrote:And lastly, going straight for the implant seems very ideal since Im single and this stuff is a hassle and one of my biggest worries was going to sleep after sex and risking priapism which is why Im increasing my units very carefully. First try I did a small amount of 3 units got me very solid but during thrusting went soft, perhaps the mono mix or higher amount will help in this department.

It's always best to use caution. Priapisms are best just avoided rather than cured.

I again encourage trying the novelty/sex shop cock rings. They may give you all of the extra boost you need.

Sometimes it does take awhile to figure out your best mix and dose.

I'm always glad to help where I can. Please remember:
I'm not a not a medical professional of any kind. Anything I post is based on my own experiences at best and hallucinations and/or delusions at worst. Internet forum advice is likely worth what you paid for it, or worse. Always ask your doctor and follow his/her advice.

Good luck.

Edited: To fix goofs.
R.R.P 2011 Mayo Jacksonville, Dr. M. Wehle. Not nerve sparing. C in margins. Radiation 2023, V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ 8 - 14 units. Originally Edex20, then compounded PGE due to cost. Inject. 12 yrs. It works. Treasure coast of FL.

Dent4ever
Posts: 48
Joined: Wed Dec 21, 2022 7:21 pm

Re: Bimix & antidote dose

Postby Dent4ever » Fri Jun 23, 2023 12:35 pm

Hey my friend,

Sorry for the late reply I just had a pet pass away.

Anyways you're right on the dot with the mix of my Bimix ingredients its 150mg Papaverine HCL/5mg Phentolamine Mesylate. As Far as the syringes go it's the 1cc total with 10, 20, 30.. etc up to 100, with 10 notches in between each. SO I reconstituted all of this in 2.5 ml of water and if say I inject and go up to the 20 -notch I though I was getting 4 units .. I guess this is quite a bit more then. Im usually very good at calculating doses but this has me confused so bad but you seem to have it down. So If I dissolved the whole vial in 2.5 ml of water am I getting 40 units at the "20" mark?? that would be quite high.. I hope im misunderstanding lol.

And Im totally with you on your last statement .. I rather avoid a priapism than have to end up at the ER.. what a hassle. Im gonna try to get mono-mix prescribed and I was grossly overcharged for my first round here.. it was $325 for the syringes (I can get a 300 of these for like 40 bucks online, a 2ml antidote and the dry mix plus bacwater. Im gonna PM you if that's okay to carry this further.
42 M. Mild peyronies like symptoms for well over a decade. Mostly related to PFS syndrome I believe. Seriously considering an Implant. Trying to mentally accept the situation, Pills barely work and trimix gel doesn't work, tried injections -hated it.

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bldoink
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Re: Bimix & antidote dose

Postby bldoink » Fri Jun 23, 2023 2:13 pm

Dent4ever wrote:Hey my friend,

[Sorry for the late reply I just had a pet pass away.

Sorry about your pet.
Dent4ever wrote:As Far as the syringes go it's the 1cc total with 10, 20, 30.. etc up to 100, with 10 notches in between each. SO I reconstituted all of this in 2.5 ml of water and if say I inject and go up to the 20 -notch I though I was getting 4 units .. I guess this is quite a bit more then.

If there's 100 marks on a 1cc/ml syringe then each mark should be one U-100 insulin unit of measurement. If you draw up twenty hash marks worth on your syringe (as described) then you're getting 20 units.
Dent4ever wrote:... So If I dissolved the whole vial in 2.5 ml of water am I getting 40 units at the "20" mark?? that would be quite high.. I hope im misunderstanding lol.

No, 20 units is 20 units. Units, as used for ED drugs, is a measurement of volume. (As used for insulin it also indicates the actual drug dose because the U-100 units are a standard for human insulin. A diabetic insulin user could probably give a better explanation. But that's not relevant for us.) Because the units, for us, are just a measurement of volume they don't specifically address the dose of the actual drug administered. It's a bit more complicated, especially as you aren't mixing the drugs and water as directed. You are correct that by using 1/2 of the water you are doubling the strength of the drug mix, so that a 1/2 dose of the reconstituted (using 1/2 the water) dose will equal the same full dose if mixed as directed with the full 5ml water.

So now we get into math, which I'm terrible at. 20 units of a mix, mixed as directed (or 30/1 per ml), should give you a dose of 6mg of Papaverine and 0.2mg of Phentolamine. (I'm multiplying the 30, from the 30mg of Papaverine per ml times the .2ml (20 units) of the dose volume. 30 X 0.2 = 6mg. Do the same with the Phentolamine so 1 X 0.2 = 0.2mg.) Using 1/2 of the water (2.5ml) doubles the potency of your 20 unit dose to 12ml Papaverine with 0.4mg of Phentolamine. Both doses are still 20 U-100 insulin units by volume. Remember, one U-100 insulin unit is just 1/100 of a cc/ml. Don't trust my math! Ask a doctor or pharmacist. Maybe someone else on the forum can double check me on this.
Dent4ever wrote:...Im gonna try to get mono-mix prescribed and I was grossly overcharged for my first round here.. it was $325 for the syringes (I can get a 300 of these for like 40 bucks online, a 2ml antidote and the dry mix plus bacwater. Im gonna PM you if that's okay to carry this further.

Remember, I'm in a minority on the mono-mix. I admit to being biased toward it. It does seem you were charged a premium price. Shop around. If you're forced to go to that pharmacy by your doctor you may consider finding a different one. Yes syringes are usually cheap. My pharmacy gives me a bunch of them with my meds if I want. What they have aren't my favorites so I usually just buy my own off of the internet. No prescription is required in my area but many jurisdictions do require a script. I recommend using the smallest capacity syringes that will hold your dose. I use less than 30 units so I use .3cc/ml syringes. My pharmacy went up on my mono-mix. I don't remember the price off hand but it wasn't any more than $165 for 10ml in ten 1ml vials. Mine comes already reconstituted in liquid form which I keep frozen. I have no experience with the antidote pricing. I'll check my PMs.

Remember, I'm not a medical professional of any kind. Always ask your doctor.
R.R.P 2011 Mayo Jacksonville, Dr. M. Wehle. Not nerve sparing. C in margins. Radiation 2023, V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ 8 - 14 units. Originally Edex20, then compounded PGE due to cost. Inject. 12 yrs. It works. Treasure coast of FL.


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