Do injections lose effectiveness over time?

Sticking a needle Where? Courage, guidance and help.
ragingbull
Posts: 76
Joined: Fri Jul 26, 2024 10:24 pm

Re: Do injections lose effectiveness over time?

Postby ragingbull » Fri Sep 13, 2024 7:41 am

Injections or pills don't lose effectiveness my dear friend.

It's the fucking ED that progressively gets worser.

NothingLikeNeedles
Posts: 24
Joined: Sat Jan 13, 2024 9:06 pm

Re: Do injections lose effectiveness over time?

Postby NothingLikeNeedles » Fri Sep 13, 2024 1:30 pm

For at least the last 3 years, I have no erections, including while asleep. With injections it is essentially 100% success rate for me.

ragingbull
Posts: 76
Joined: Fri Jul 26, 2024 10:24 pm

Re: Do injections lose effectiveness over time?

Postby ragingbull » Fri Sep 13, 2024 3:19 pm

NothingLikeNeedles wrote:For at least the last 3 years, I have no erections, including while asleep. With injections it is essentially 100% success rate for me.


What dose works best for you? From which dosage did you start and what interval did you use for titration? Thanks.

NothingLikeNeedles
Posts: 24
Joined: Sat Jan 13, 2024 9:06 pm

Re: Do injections lose effectiveness over time?

Postby NothingLikeNeedles » Sat Sep 14, 2024 12:44 am

Between 12 and 20 units. Same prescription for last 6 years.

NothingLikeNeedles
Posts: 24
Joined: Sat Jan 13, 2024 9:06 pm

Re: Do injections lose effectiveness over time?

Postby NothingLikeNeedles » Sat Sep 14, 2024 12:49 am

Papaverine Hydrochloride, Phentolamine Mesylate, and Protaglandin EI. My ratio is 30MG/1MG/20MCG per ML
Don't know what it was before 2019.

qcswral
Posts: 271
Joined: Sun Feb 10, 2013 8:01 pm
Location: Martin County FL

Re: Do injections lose effectiveness over time?

Postby qcswral » Wed Sep 18, 2024 10:45 pm

From what I've read and been told it's not the Trimix that looses its effectiveness but the underlying cause(s) for your ED gets worse over time. If it's a circulatory issue, as with me, it's just more clogging of the vessels providing blood to the penis. I suppose there are cases where the Trimix lost its potency. I have been injecting Trimix for close to 15 years now at 1-2 times per week and over that time I have had to increase the dosage. Just 6 months I began injecting Quad-Mix at a low dose which has been working great.Every person is very different and the causes for ED vary...but if it's caused by poor blood flow, diabetes etc....it's usually the underlying medical condition is progressing.
70 year old legally separated retired health-care professional. ED began in my early 50's. Viagra worked great for about 5 years, then had cardiac by-pass surgery and eventually moved to injections about 10 years ago.

Donkeykong
Posts: 67
Joined: Thu Aug 08, 2024 4:26 pm

Re: Do injections lose effectiveness over time?

Postby Donkeykong » Thu Sep 19, 2024 5:36 pm

ragingbull wrote:Injections or pills don't lose effectiveness my dear friend.

It's the fucking ED that progressively gets worser.


I feel like that is an excuse used by doctors to evade blame and liability. The old story of blaming the patient.

Trimix definitely causes fibrosis and scar tissue in many guys, causing worse ED. Dr. Eid told me this. He is not a fan of it and he says alprostadil alone is better.

ragingbull
Posts: 76
Joined: Fri Jul 26, 2024 10:24 pm

Re: Do injections lose effectiveness over time?

Postby ragingbull » Thu Sep 19, 2024 6:20 pm

alprostadil alone is better.


Is it called monomix?

Donkeykong
Posts: 67
Joined: Thu Aug 08, 2024 4:26 pm

Re: Do injections lose effectiveness over time?

Postby Donkeykong » Fri Sep 20, 2024 3:58 pm

ragingbull wrote:
alprostadil alone is better.


Is it called monomix?


Sometimes yes. Sometimes it's also called Prostaglandin E1 or PGE1.


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