Tri-Mix and anorgasmia

Sticking a needle Where? Courage, guidance and help.
CanGetItUpButNotOff
Posts: 211
Joined: Mon Sep 20, 2021 1:34 pm

Re: Tri-Mix and anorgasmia

Postby CanGetItUpButNotOff » Fri Jan 24, 2025 7:58 pm

Donkeykong wrote:If it works then great, but for me I find tadalafil doesn't engorge the glans, just the corpora. Tadalafil is also sometimes used as a treatment for P.E. since it tends to delay ejaculation, so I think it is not just me. Vardenafil (levitra) engorges the glans much more and has best sensitivity and sildenafil (viagra) comes second in my experience, but YMMV.

I hadn't heard that before. I'll have to research Tadalafil for PE - that would take me off Tadalafil ASAP.

I've never tried Vardenafil but if it improves sensitivity, I'll get an Rx.
Born 1954. Diabetes, hypertension and atherosclerosis. Sildenafil is iffy. Tri-Mix (30/3/20 Pap/Phen/PGE1) a godsend pending long-term efficacy. Daily Cialis. Tried LiESWT, Botox, PT-141, Eroxon, QST, DUS, Vertica, cabergoline, psychotherapy+hypnotherapy.

sputnik
Posts: 8
Joined: Sat Jan 09, 2021 5:22 am

Re: Tri-Mix and anorgasmia

Postby sputnik » Sat Jan 25, 2025 8:13 am

I have been a successful injector of tri-mix for nearly 15 years. My wife and I are also on TRT and have a very ambitious sex life. When I am highly aroused and my erection is extra hard there is a noticeable delay in orgasm which does create a small problem as my wife is very orgasmic. Any delay's in my ejaculation result in withdrawal and finishing by hand or orally. I do use the firmtech cock rings which help retain blood in the gland and improve the force of emission. Both my wife and I are 70+ and actively work together and enjoy our lives! :D :D

CanGetItUpButNotOff
Posts: 211
Joined: Mon Sep 20, 2021 1:34 pm

Re: Tri-Mix and anorgasmia

Postby CanGetItUpButNotOff » Mon Jan 27, 2025 8:21 am

A quick update (from the OP). My Tri-Mix use is still in the early stages, about 10 weeks in, so around 20 shots. Except for one instance where there were extenuating circumstances, I've been able to orgasm every time on TriMix. This is amazing! In my recent history, I was accustomed to about a 50% success rate. When I started Tri-Mix, I was pessimistic because 1) reports led me to believe it was more likely to inhibit orgasm, and 2) having a reliable erection without the ability to complete the deed was only more frustrating. Everything with this 70-year old body is subject to change so I can only ride this new paradigm for as long as it lasts. Life is day-by-day.
Born 1954. Diabetes, hypertension and atherosclerosis. Sildenafil is iffy. Tri-Mix (30/3/20 Pap/Phen/PGE1) a godsend pending long-term efficacy. Daily Cialis. Tried LiESWT, Botox, PT-141, Eroxon, QST, DUS, Vertica, cabergoline, psychotherapy+hypnotherapy.

Martin6469
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Joined: Tue Feb 18, 2020 12:22 pm
Location: St. Louis, USA

Re: Tri-Mix and anorgasmia

Postby Martin6469 » Wed Jan 29, 2025 12:08 am

Sputnik and Cangetit: I'm a Trimix injector and I find that a less-hard erection, with a less-bulging and softer glans, is less likely to have anorgasmia.
Age 79 in 2024. On testosterone replacement due to hypothalamus malfunction. (Attention depressed guys: low testosterone is a cause.) Healthy health nut but ED due to getting old. Like to keep enough cardiovascular ability to thrust for 30 min.

CanGetItUpButNotOff
Posts: 211
Joined: Mon Sep 20, 2021 1:34 pm

Re: Tri-Mix and anorgasmia

Postby CanGetItUpButNotOff » Wed Jan 29, 2025 8:53 am

Martin6469 wrote:Sputnik and Cangetit: I'm a Trimix injector and I find that a less-hard erection, with a less-bulging and softer glans, is less likely to have anorgasmia.
Your comment intrigues me. I wonder why that is for you. As a result, do you dial-down your TriMix formula so that you are less hard? Might it be that your improved sensitivity comes from injecting less formula? Or, perhaps, the bulging erection itself causes the shaft and glans to be less sensitive? If you max out the formula, do you border on a painful or uncomfortable feeling (if so, that would certainly make it harder for me to cum)?
Born 1954. Diabetes, hypertension and atherosclerosis. Sildenafil is iffy. Tri-Mix (30/3/20 Pap/Phen/PGE1) a godsend pending long-term efficacy. Daily Cialis. Tried LiESWT, Botox, PT-141, Eroxon, QST, DUS, Vertica, cabergoline, psychotherapy+hypnotherapy.

Martin6469
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Joined: Tue Feb 18, 2020 12:22 pm
Location: St. Louis, USA

Re: Tri-Mix and anorgasmia

Postby Martin6469 » Thu Jan 30, 2025 1:05 pm

It seems to be that the larger glans with more-separated nerves is less sensitive. I know that that doesn't seem to make sense, but that's my best explanation. I noticed this years ago, before ED, when I used the stretchy penis sleeves at the base to try to make my erection thicker. I've been injecting now for eight years and I know exactly how much Trimix gives me the slightly less-than-full rigidity that I want. (I keep a full log of all the injection parameters, including the side injected, because left and right need different amounts.)

I've been very careful, even when I began injecting, to not get to a painful erection, because that would likely lead to an over-four-hour problem.

(I know that dialing up and down is difficult for you because of your 0.3ml syringes. Biological supply companies do have smaller syringes, but your druggist would have to send for them for you. They won't sell directly to just anybody, or they'd get into trouble with drug enforcement people.)
Age 79 in 2024. On testosterone replacement due to hypothalamus malfunction. (Attention depressed guys: low testosterone is a cause.) Healthy health nut but ED due to getting old. Like to keep enough cardiovascular ability to thrust for 30 min.

texcal56
Posts: 54
Joined: Tue Apr 15, 2014 9:36 am

Re: Tri-Mix and anorgasmia

Postby texcal56 » Fri Jan 31, 2025 6:51 am

My experience sounds different. My E.D. Is caused by Multiple Sclerosis. When I first started having sex, I usually lasted less than 5 minutes (20’s and 30’s). When my ED first started in my 40’s, I also experienced some delayed orgasms. When I began injecting trimix in my 50s, I began experiencing anorgasmia, especially with PIV sex. My wife, who I met when I first began injecting, was disappointed that I could not cum inside her and I had to pullout and masturbate to finish. We experimented with a bunch of positions and I finally achieved an internal PIV orgasm when she rides me in Reverse Cowgirl. Through lots of experience, we have figured out which positions work best for her orgasms to start and then usually finish in Reverse Cowgirl.
Age 68, retired in Costa Rica. ED related to relapsing remitting MS. Increasing doses of Viagra worked for 10 yrs. Been injecting trimix for last 10 yrs with >95% effectiveness. Erection 10/10 for 2 hours.

CanGetItUpButNotOff
Posts: 211
Joined: Mon Sep 20, 2021 1:34 pm

Re: Tri-Mix and anorgasmia

Postby CanGetItUpButNotOff » Fri Jan 31, 2025 8:23 am

My experience is that very few positions work for me; in fact, it really is just one: missionary. Blow jobs used to be my favorite but it's been more than a year since that worked. For PIV, I think I need the control over thrusting angle and pace is necessary for me to get off. Plus missionary gives me a nice view of her body and I can sneak a peek of me going in and out of her. I did climax once a couple of weeks ago in a side-by-side configuration but, other than that, every orgasm has been missionary raised up over her for a good view.

But I also have to report an anorgasmia failure yesterday, the first in the last month. So, my optimism that Tri-Mix is a panacea is diminished. :x I'm trying to assess whether this was random or if I can attribute it to some identifiable factor. My refractory period was 3½ days and that's usually sufficient. We were both turned on and she had a wonderful - and stimulating for me - orgasm, so that was a positive factor. The Tri-Mix was working, although it flagged shortly after I gave up. Another possibility is that my oral testosterone Rx (Kyzatrex) had run out a couple of days earlier and it's possible my previous success was due to a boost in T that was now missing.
Born 1954. Diabetes, hypertension and atherosclerosis. Sildenafil is iffy. Tri-Mix (30/3/20 Pap/Phen/PGE1) a godsend pending long-term efficacy. Daily Cialis. Tried LiESWT, Botox, PT-141, Eroxon, QST, DUS, Vertica, cabergoline, psychotherapy+hypnotherapy.

CanGetItUpButNotOff
Posts: 211
Joined: Mon Sep 20, 2021 1:34 pm

Re: Tri-Mix and anorgasmia

Postby CanGetItUpButNotOff » Thu Feb 20, 2025 7:21 am

CanGetItUpButNotOff wrote:But I also have to report an anorgasmia failure yesterday, the first in the last month. So, my optimism that Tri-Mix is a panacea is diminished. :x I'm trying to assess whether this was random or if I can attribute it to some identifiable factor. My refractory period was 3½ days and that's usually sufficient. We were both turned on and she had a wonderful - and stimulating for me - orgasm, so that was a positive factor. The Tri-Mix was working, although it flagged shortly after I gave up. Another possibility is that my oral testosterone Rx (Kyzatrex) had run out a couple of days earlier and it's possible my previous success was due to a boost in T that was now missing.

Sorry for quoting myself, but things are a little quiet in the injections forum so I thought I'd give an update.

My initial sky-high optimism has now given way to deep pessimism. My success rate has declined to about one out of four, and now if I don't have a refractory period of at least 5 days, there's really no chance.

On my list to try: 1) getting an Rx for vardenafil, 2) backing down the trimix to a less hard erection, 3) skipping Tri-Mix and using viagra.

On a positive note, my one success in the last 10 days was from a CIM blowjob - my first in a year.

I'm also pursuing more aggressive medical approaches to addressing the anargasmia. My urologist has put me in touch with a spinal surgeon who has some diagnostic techniques to check for nerve damage being the root cause, which I suspect is the case. The end game is probably not surgery but an anti-inflammation shot that may or may not help.
Born 1954. Diabetes, hypertension and atherosclerosis. Sildenafil is iffy. Tri-Mix (30/3/20 Pap/Phen/PGE1) a godsend pending long-term efficacy. Daily Cialis. Tried LiESWT, Botox, PT-141, Eroxon, QST, DUS, Vertica, cabergoline, psychotherapy+hypnotherapy.

mrksman
Posts: 28
Joined: Wed Jan 19, 2022 11:14 pm

Re: Tri-Mix and anorgasmia

Postby mrksman » Thu Feb 20, 2025 10:51 am

“On my list to try: 1) getting an Rx for vardenafil, 2) backing down the trimix to a less hard erection, 3) skipping Tri-Mix and using viagra.”

Can’t - We’re you able to get the script for Vardenafil? I got a script from my Doc for it but when I tried to get if filled my pharmacist said my insurance would not cover it and to purchase out of pocket would cost over $500. Hopefully you are having better luck?
Age 58, happily married over 38 years. T levels fluctuate but often on the low end. Cialis (Tadalafil) was working great but not so much lately. Same with Viagra. Use a Vacurect VED with a PosTVac Mach Ring as a backup.


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