Fibrosis detection

Sticking a needle Where? Courage, guidance and help.
CanGetItUpButNotOff
Posts: 240
Joined: Mon Sep 20, 2021 1:34 pm

Fibrosis detection

Postby CanGetItUpButNotOff » Wed Mar 19, 2025 6:22 pm

I'm fairly new to injections - 4 months - regularly every 3 or 4 days. Is a 30/3/20 Tri-Mix. I do all the recommended procedures of varying the injection site, cleanly inserting the needle at a 90° angle, compressing the site, etc. Only very infrequent bruising so I think I'm doing a pretty good job. But I am paranoid about scarring.

I regularly - quarterly - have my urologist check for any signs of problems and see nothing so far. But, then again, I'm only 4 months into it. My question is about early detection of scarring. If fibrosis is occurring, will a trained urologist be able to detect it in time for me to enact preventive measures? Or is it more like, "Oops, you've got peyronies! Too late."
Born 1954. Diabetes, hypertension and atherosclerosis. Sildenafil is iffy. Tri-Mix (30/3/20 Pap/Phen/PGE1) a godsend pending long-term efficacy. Daily Cialis. Tried LiESWT, Botox, PT-141, Eroxon, QST, DUS, Vertica, cabergoline, psychotherapy+hypnotherapy.

RJ_in_Pa
Posts: 142
Joined: Tue Oct 17, 2023 4:34 pm
Location: Pa

Re: Fibrosis detection

Postby RJ_in_Pa » Wed Mar 19, 2025 7:48 pm

I noticed and my Uro confirmed that I have fibrosis. Feels like a vein running along the left side of my penis, but it’s definitely not a vein. My Uro said it is not uncommon for those that had an RP to have fibrosis due to the trauma from the surgery.

I have never heard that there is a connection between fibrosis and PD. I was under the impression that PD was caused by scarring, but not sure how Pd is caused by injections.

Can anyone give us some insight on this?

Thanks,
RJ
64, Radical Prostatectomy in 2023, pills did nothing. Currently on Trimix with great success.

wolfpacker
Posts: 1250
Joined: Thu Dec 12, 2013 10:16 pm

Re: Fibrosis detection

Postby wolfpacker » Wed Mar 19, 2025 8:25 pm

RJ_in_Pa wrote:I noticed and my Uro confirmed that I have fibrosis. Feels like a vein running along the left side of my penis, but it’s definitely not a vein. My Uro said it is not uncommon for those that had an RP to have fibrosis due to the trauma from the surgery.

I have never heard that there is a connection between fibrosis and PD. I was under the impression that PD was caused by scarring, but not sure how Pd is caused by injections.

Can anyone give us some insight on this?

Thanks,
RJ


Fibrosis=scarring
Early 30s with ED from jelqing. Implant by Dr Eid on 24 June 2021 with a Titan 24cm with +1cm RTE on one side and -1cm cut off on the other side

Aug 2024 revision to AMS CX 24cm + 2rte

My journal: viewtopic.php?t=17202

Bambino09
Posts: 208
Joined: Fri Jul 28, 2023 5:30 pm

Re: Fibrosis detection

Postby Bambino09 » Wed Mar 19, 2025 10:09 pm

wolfpacker wrote:
RJ_in_Pa wrote:I noticed and my Uro confirmed that I have fibrosis. Feels like a vein running along the left side of my penis, but it’s definitely not a vein. My Uro said it is not uncommon for those that had an RP to have fibrosis due to the trauma from the surgery.

I have never heard that there is a connection between fibrosis and PD. I was under the impression that PD was caused by scarring, but not sure how Pd is caused by injections.

Can anyone give us some insight on this?

Thanks,
RJ


Fibrosis=scarring


Can you speck me? I have 32 years old!!

misterecz
Posts: 120
Joined: Thu Dec 15, 2022 1:42 am
Contact:

Re: Fibrosis detection

Postby misterecz » Wed Mar 19, 2025 10:26 pm

If you want to be proactive about scarring. I recommend that you pump every day (not necessarily the day after an injection) this allows your penis to stay healthy and helps make sure that scarring does not form.
Peyronie's From Rough Sex in 2020.
Developed Erectile Dysfunction, Dorsal, & Lateral Curvature.
Treated With Traction, VED, DMSO, & PGE1.
YouTube Channel: https://www.youtube.com/@mrecz

wolfpacker
Posts: 1250
Joined: Thu Dec 12, 2013 10:16 pm

Re: Fibrosis detection

Postby wolfpacker » Thu Mar 20, 2025 7:14 am

Bambino09 wrote:
wolfpacker wrote:
RJ_in_Pa wrote:I noticed and my Uro confirmed that I have fibrosis. Feels like a vein running along the left side of my penis, but it’s definitely not a vein. My Uro said it is not uncommon for those that had an RP to have fibrosis due to the trauma from the surgery.

I have never heard that there is a connection between fibrosis and PD. I was under the impression that PD was caused by scarring, but not sure how Pd is caused by injections.

Can anyone give us some insight on this?

Thanks,
RJ


Fibrosis=scarring


Can you speck me? I have 32 years old!!


Speck you? I'm not sure what you mean.
Early 30s with ED from jelqing. Implant by Dr Eid on 24 June 2021 with a Titan 24cm with +1cm RTE on one side and -1cm cut off on the other side

Aug 2024 revision to AMS CX 24cm + 2rte

My journal: viewtopic.php?t=17202

CanGetItUpButNotOff
Posts: 240
Joined: Mon Sep 20, 2021 1:34 pm

Re: Fibrosis detection

Postby CanGetItUpButNotOff » Thu Mar 20, 2025 8:04 am

misterecz wrote:If you want to be proactive about scarring. I recommend that you pump every day (not necessarily the day after an injection) this allows your penis to stay healthy and helps make sure that scarring does not form.


I do pump pretty regularly, probably 4 or 5 days each week.

As a further data point, I note that different urologists have different opinions on the cause of scarring. I personally see two different urologists and each one of them says that the chemicals are not likely to cause scarring but just poor injection technique that causes trauma to the tunica. OTOH, there are reports here (frequently quoting Dr. Eid) that implant patients usually, or often, present with scarring from Past ICI with Tri-Mix, but not so much from just Alprostadil mono-mix. Separately, I wrote another doctor who performs a lot of implants and asked the question; his response:
Corporal fibrosis from a history of ICI use is extremely common. I attribute it to the compounds being used rather than the mechanical action of the needle itself.


I can't think of any topic that has such widely diverse opinions from the experts.
Born 1954. Diabetes, hypertension and atherosclerosis. Sildenafil is iffy. Tri-Mix (30/3/20 Pap/Phen/PGE1) a godsend pending long-term efficacy. Daily Cialis. Tried LiESWT, Botox, PT-141, Eroxon, QST, DUS, Vertica, cabergoline, psychotherapy+hypnotherapy.


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