With trimix what ingredient controls erection strength?

[basil1492]

Hi, finally managed to find a way to get trimix over in the UK, basically i make my own and am currently using a 30/2/20mcg mix. Ive worked my way up from 10 units to 30 units and from 20 units up nothing has changed. I get a 70-80% erection lasting 2.5hrs. Now im more than happy with the time but would like stronger erections. I've read that the bigger dose you use the longer it lasts with no extra firmness but i wondered if i made a different mix what ingredient would i need to make bigger to affect the erection strength, papaverine, phentolamine or the PGE1?

[ocitgo]

Standard prescriptions

https://empower.pharmacy/drugs/tri-mix-injection.html

Also This may help

http://www.ncbi.nlm.nih.gov/pubmed/7966797

The lowest effective dose of prostaglandin E1 as treatment for erectile dysfunction.
Chen J1, Godschalk M, Katz PG, Mulligan T.
Author information
Abstract
The recommended dose of prostaglandin E1 as treatment for erectile dysfunction has been reported to be 10 to 40 micrograms. However, adverse effects probably increase with increasing doses. We conducted a prospective, single-blind, dose-escalating study of prostaglandin E1 on 20 men with erectile dysfunction of various etiologies. The response to prostaglandin E1 was assessed by penile palpation and RigiScan rigidity monitoring. A total of 17 patients completed the study: 1 achieved rigidity with 1 microgram., 2 with 2 micrograms. and 4 with 3 micrograms. prostaglandin E1, while more than 70% achieved rigidity with 5 micrograms. or less and more than 80% had a full erection with 20 micrograms. Of 138 injections there were 2 episodes of pain after injection. We conclude that the often recommended starting dose of 20 micrograms. is too high. A more appropriate starting dose is 2.5 micrograms. with increments of 2.5 micrograms. until the lowest effective dose is achieved. This approach may lessen the major impediments to prostaglandin E1 use, that is burning and pain.

"A total of 17 patients completed the study:

1 achieved rigidity with 1 microgram.,
2 with 2 micrograms. and
4 with 3 micrograms. prostaglandin E1,
70% achieved rigidity with 5 micrograms. or less and
+80% had a full erection with 20 micrograms"

[basil1492]

Thanks Ocitgo, i've read that before but it doesn't say which is the most important for rigidity. As it happens i'm using 20mcg/ml and taking about 25 units so about 5mcg every dose. If you work out the others with 30mg/ml papaverine and 2mg/ml phentolamine then im acutally takine 7.5/0.5/5mcg per dose so going by your list im taking an amount which gave 70% rigidity. I'm nowhere near rigid, maybe a 70-80% erection at best but jumping up to 20mcg (which would mean 80mcg/ml) is a very big jump. I may double the pge1 next batch to see if it helps but i wasn't sure which of the 3 had the most significance to how rigid i'd get as opposed to which ones just lengthened the time.

[rooster]

The following thread may be of some help with your question

http://www.excelmale.com/showthread.php ... &highlight

[basil1492]

Thanks Rooster, i searched for days looking for such a thread, much appreciated. Looks like on my next batch i just need to up the dose of PGE1 then as the time it works is great, funny how it didnt change though with larger doses. As i said before anything from 15 to 30 units all gives the same 2.5hrs or so.

[rooster]

Basil

I was using a formula 25-1-25. Was not getting a full erection but maybe 10 minutes and then just plump for next hour. The amount of the dosage did not seem to matter much, up to 60 units. My pharmacist was concerned about going over 70 units-volume issues.

I explained to urologist what I was getting from the formula and he changed it to 30-4-25, leaving the Pge1 at 25. This new formula gives me a very full erection with small dosage (10 units-20 units) for about 15-20 minutes, then erection returns with a little stimulation, the more I inject the longer the erection without the manual stimulation. Thinking that by upping the dose will give me the time that I am looking for with the non stimulated erection.

[basil1492]

That seems to indicate the pge1 doesnt affect the strength of the erection. If anything it points to the phentolamine which changed from 1mg to 4mg as the main thing that got the erection stronger. Is that how you see it?

[rooster]

Not sure, I went from 25-1-25 to 30-4- 25. Per the link the first two determine how long erection will last, the third pge1 is what gives erection.

With first formula I would get erection but did not last, with second formula now it is lasting.

Look back at the link, I think it is the pge1 in your formula of 30-2-20. You have hardness issue, not timing issue.

I am no expert, may want to ask other forum for another opinion.

[basil1492]

Thanks Rooster, I misunderstood. Where you said "was not getting a full erection" with the old formula then went to a new formula where the more you inject the firmer the erections i thought it was a case of the bits that were changed meant a firmer erection, eg the papaverine and phentolamine (mainly this one). What i may be tempted to do is make a few smaller 1ml batches just to test what needs to increase then use the same units from each batch to see the differences, perhaps it affects different people different ways i mean.

[oowright]

I'd like to try some trimix on one side for no-pain and ten minutes later, some caverject on the other side for EQ. Want some opinions first though ...