Good summary of benefits of using VED for penis health:
Yuan, J., Hoang, A., Romero, C. et al. Vacuum therapy in erectile dysfunction—science and clinical evidence. Int J Impot Res 22, 211–219 (2010). https://doi.org/10.1038/ijir.2010.4
From the above medical journal:
“Our preliminary data indicated that daily VED therapy significantly improved the intracavernosal pressure/mean artery pressure ratio, preserved penile length and girth, decreased the level of hypoxia-inducible factor-1α, transforming growth factor-β1, collagen and apoptosis, and increased the level of eNOS and α-smooth-muscle actin.87 (https://www.nature.com/articles/ijir20104#ref-CR87)”
Change in size or shape after stopping injections?
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