Trying aprostadil again after a bad experience
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Re: Trying aprostadil again after a bad experience
Never Enough: You might be a "Hard/Flaccid" sufferer. This curious condition has its own topic here, and there's an interesting post from another UK resident Fed1981 in that topic: "Hard Flaccid - Success Story..." 9-3-20. His original complaint was in General Discussion "27-year-old pump injury..." 8-1-20.
Age 79 in 2024. On testosterone replacement due to hypothalamus malfunction. (Attention depressed guys: low testosterone is a cause.) Healthy health nut but ED due to getting old. Like to keep enough cardiovascular ability to thrust for 30 min.
Re: Trying aprostadil again after a bad experience
I’ve got my dosage adjusted now where I don’t have to worry at all about going soft (eliminating angst) but not so much where I stay rock hard after ejaculating. I posit that there could be a “ married” dose and a “ dating” dose. Even a higher dating dose should be well short of causing any risk of priapism. I haven’t tried injections yet outside of wedlock but I plan to do so in due course if binge sex is on the table ( I gave up on mistresses several years ago due to my ED, not to mention the stress). I’m pretty sure I could do three rounds we the right dose.
63yr old. PDwith 40% dor. Curve. Pre-PD 7”x6”.lost 2 in. due to PD. ED prior to PD. Switched from Sildalifil to Trimix Nov 2023 . Currently titrating Trimix for optimization.
Re: Trying aprostadil again after a bad experience
Sorry for the post. I cant add to much to the thread....Yet
. There is some excellent advice regarding the mental effects of ED and injecting. Our mental state has a great deal to do with our physical state.

1955. I have had ED for years. We were going for a Rigicon Infla10 in October 2024. Life got in the way (heart attack & stent), so we are now going for injections as a fill-in.
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Re: Trying aprostadil again after a bad experience
A pretty normal tadalafil/cialis on-demand dose is 20 mg, so you might want to try upping your previous 15 mg dose. Tadalafil is also different from Viagra in that it stays in your system longer but for a lot of guys it takes much longer to kick in, so for best results they take it the morning or even the the night before.
Alprostadil ache is common. In my case I won't get the ache as long as I have sex while I'm hard. If you just let it sit, though, it will ache.
Alprostadil ache is common. In my case I won't get the ache as long as I have sex while I'm hard. If you just let it sit, though, it will ache.
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Re: Trying aprostadil again after a bad experience
Also, yes, high anxiety can overcome alprostadil. The mixes with papaverine are more likely to punch through anxiety and don't ache as much, but are said by some doctors to be more likely to cause worsening ED than alprostadil alone.
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Re: Trying aprostadil again after a bad experience
Donkeykong wrote:Also, yes, high anxiety can overcome alprostadil. The mixes with papaverine are more likely to punch through anxiety and don't ache as much, but are said by some doctors to be more likely to cause worsening ED than alprostadil alone.
Really? I dont get injections. Some say all penile injections bypass anxiety and then sometimes they don't. If they didnt hoqw would they be used for doppler tests? There's no way anyone's getting a natural erection in that kind of setting. The ones I would be using contain Aviptadil and PheNTalomine.
39 m UK
Psych ED since forever less problems being erect alone.
3 kids. Long term partner.
CPPS pudendal neuralgia and muscle tightness in late 2023 making ED worse.
Cialis no longer works. Sildenafil 100mg with diazepam works some of the time.
Psych ED since forever less problems being erect alone.
3 kids. Long term partner.
CPPS pudendal neuralgia and muscle tightness in late 2023 making ED worse.
Cialis no longer works. Sildenafil 100mg with diazepam works some of the time.
Re: Trying aprostadil again after a bad experience
I have just started using Aprostadil (25mcg strength )and learning how many units to use. No pain. just the prick
It's great to have an active member again. I am wondering if the pain is an indication of your prescription being too strong.

1955. I have had ED for years. We were going for a Rigicon Infla10 in October 2024. Life got in the way (heart attack & stent), so we are now going for injections as a fill-in.
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- Posts: 190
- Joined: Thu Aug 08, 2024 4:26 pm
Re: Trying aprostadil again after a bad experience
Never_Enough wrote:Donkeykong wrote:Also, yes, high anxiety can overcome alprostadil. The mixes with papaverine are more likely to punch through anxiety and don't ache as much, but are said by some doctors to be more likely to cause worsening ED than alprostadil alone.
Really? I dont get injections. Some say all penile injections bypass anxiety and then sometimes they don't. If they didnt hoqw would they be used for doppler tests? There's no way anyone's getting a natural erection in that kind of setting. The ones I would be using contain Aviptadil and PheNTalomine.
I've had a couple Doppler tests, one with two injections of trimix and another with a high dose of alprostadil, and they couldn't get me hard. So effectiveness of the injections is indeed dependent on anxiety level in my experience.
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Re: Trying aprostadil again after a bad experience
John Dday wrote:I have just started using Aprostadil (25mcg strength )and learning how many units to use. No pain. just the prickIt's great to have an active member again. I am wondering if the pain is an indication of your prescription being too strong.
Doubt it. I had literally a tiny dose.. 2.5 units I could get a better erection without anything.
In my limited injection experience I think the anxeity and issues with needles is going to make them a non starter for me. Its frustrating because pills dont always work... but alone I can get a great erection most of the time.
So theres nothing else between pills and implant..ED options really are poor given the importance to so many men.
39 m UK
Psych ED since forever less problems being erect alone.
3 kids. Long term partner.
CPPS pudendal neuralgia and muscle tightness in late 2023 making ED worse.
Cialis no longer works. Sildenafil 100mg with diazepam works some of the time.
Psych ED since forever less problems being erect alone.
3 kids. Long term partner.
CPPS pudendal neuralgia and muscle tightness in late 2023 making ED worse.
Cialis no longer works. Sildenafil 100mg with diazepam works some of the time.
Re: Trying aprostadil again after a bad experience
Never-enough. What was the strength of your alprostadil? Mine is 20mcg (you can get much stronger). I am using 20 Units of my strength. I might try 25. It is working for me. Having a sympathetic partner helps. A lot of ED is also in the mind, but we can 'learn' or re-learn new mental images of ourselves.
1955. I have had ED for years. We were going for a Rigicon Infla10 in October 2024. Life got in the way (heart attack & stent), so we are now going for injections as a fill-in.
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