Silly question but...
Has anyone here had an erection lasting longer than 4 hours ever had any serious damage because of it?
Long story short, I took trimix about 2 months ago and my erection lasted about 6-8 hours. It was in full size for 4 hours then gently started dying down at the 6 hour mark. So was about 8 hours or so that I had some type of erection. Was not in any kind of pain.
Is this anything to worry about in terms of damaging tissue? Reason I'm paranoid is cause I hear erections lasting more than 4 hours lead to permanent damage in tissue and/or "size". How would I know if I "lost" any size in my erection due to this or caused some damage? I can't really tell. Doesn't seem like anything happened but it's been stuck on my mind all day and I keep thinking I lost some "size" or caused some damage due to this.
Trimix..tissue damage?
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Re: Trimix..tissue damage?
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Last edited by bldoink on Wed Jul 23, 2025 12:16 am, edited 1 time in total.
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Re: Trimix..tissue damage?
My very first injection (in the doctor's office and by the doctor) was 30 units. Five hours later, I was 85% - 90% as hard as I was in the beginning and I called the clinic to see what to do. Doc said I was okay as long as "deflation" was underway, even if slowly. It took another 3 or 4 hours to get down to "normal", but everything was fine.
His instructions for next time were to cut the dosage in half EACH TIME until I reached the right balance of "as hard as I wanted for as long as I wanted", but not hours on end: "no all night orgies". And then to go up and/or down 1 unit at a time to find the sweet spot. That "sweet spot" dosage turned out to be 4 to 6 units.
I'm glad to answer any questions at any time.
Peace out.
His instructions for next time were to cut the dosage in half EACH TIME until I reached the right balance of "as hard as I wanted for as long as I wanted", but not hours on end: "no all night orgies". And then to go up and/or down 1 unit at a time to find the sweet spot. That "sweet spot" dosage turned out to be 4 to 6 units.
I'm glad to answer any questions at any time.
Peace out.
Born 1948, wed 1969. BPH & Type II Diabetes at age 35. TURP-2002; ED even before that--diabetes. Cardiac valve surgery: 2007 & 2019. Poor results with pills. Started trimix injections in Nov, 2010. Great results from the very beginning.
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Re: Trimix..tissue damage?
My first injection was 10 units of quad mix which caused a 6 or so hour erection that was so hard I couldn't walk. I freaked out, and it was painful but the next day I was fine. I now take 6 units of a weaker formula and get a 4 hour boner. I keep the Sudafed and Terbutaline nearby though.
I do find that my rare natural erections are a lot more enjoyable because when I am on the Trimix, I have a bit of pain and seem to lose a lot of sensitivity
I am hoping to eventually not need the Trimix, but pills don't do much now for me. The whole refrigerator thing and time to inject ruins any spontaneity
I do find that my rare natural erections are a lot more enjoyable because when I am on the Trimix, I have a bit of pain and seem to lose a lot of sensitivity
I am hoping to eventually not need the Trimix, but pills don't do much now for me. The whole refrigerator thing and time to inject ruins any spontaneity
54 year old, good shape, treated with HDR Brachy monotherpy at UCLA in 2017 for 4+3 Gleason prostate cancer with PSA of 20. Moderate success with Cialis and Viagra,now trying Quadmix
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Re: Trimix..tissue damage?
Doing a search for terbutaline led me to this thread.
BTW, here's NCBI article on terbutaline:
https://pubmed.ncbi.nlm.nih.gov/14999218/
Had an erection for ~5 hours from my first .1 ml (10 units) of Trimix 105. Had the injection to get a Doppler U/S. Wasn't painful. Had to be drained at the ER....ghastly experience.
I got several of the phenylephrine shots....like 3 IIRC, before the ER doc decided to just drain it. Must've hit a vein the first time in....or accidentally injected air from the syringe as I ended up with a huge 1" or so hemorrhage/hemotoma on the side of the shaft.
I wondered at the time if I shouldn't have just let it ride considering how bad the guy fucked me up draining it.
BTW, here's NCBI article on terbutaline:
https://pubmed.ncbi.nlm.nih.gov/14999218/
Had an erection for ~5 hours from my first .1 ml (10 units) of Trimix 105. Had the injection to get a Doppler U/S. Wasn't painful. Had to be drained at the ER....ghastly experience.
I got several of the phenylephrine shots....like 3 IIRC, before the ER doc decided to just drain it. Must've hit a vein the first time in....or accidentally injected air from the syringe as I ended up with a huge 1" or so hemorrhage/hemotoma on the side of the shaft.
I wondered at the time if I shouldn't have just let it ride considering how bad the guy fucked me up draining it.
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Re: Trimix..tissue damage?
That's the main problem for me with Trimix, then Bimix- finding that sweet spot to not need to inject the antidote.
Ive gone to the 4 hour (a couple of times 6) mark many times, and the one thing I've noticed is a loss of sensitivity, initially during the injection time, and now all the time. I'm taking a break and going back to pills, as the pills are unreliable but when I do get hard, it's easier to ejaculate. With injections I can't ejaculate, without injections I could but it takes longer now.
I've been doing weekly 2 sex sessions, and with the Trimix I just think my penis needs a rest from Trimix, and a rest from the marathons in general. My glan nerves need a rest, and I'm using Man1 penile creamless, bought the manhood penis cover. gentle masturbating, and I'm getting on Wellbutrin that they say helps a person ejaculate more quickly.
Ive gone to the 4 hour (a couple of times 6) mark many times, and the one thing I've noticed is a loss of sensitivity, initially during the injection time, and now all the time. I'm taking a break and going back to pills, as the pills are unreliable but when I do get hard, it's easier to ejaculate. With injections I can't ejaculate, without injections I could but it takes longer now.
I've been doing weekly 2 sex sessions, and with the Trimix I just think my penis needs a rest from Trimix, and a rest from the marathons in general. My glan nerves need a rest, and I'm using Man1 penile creamless, bought the manhood penis cover. gentle masturbating, and I'm getting on Wellbutrin that they say helps a person ejaculate more quickly.
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Re: Trimix..tissue damage?
My Dr. explained that at 4 hours (non-bionic) the blood pools and lacks oxygen, so some tissue necrosis will take place. Not good to do, and in bad cases can lead to gangrene.
AMS700 CX 21cm with 3 RTE 4-2019 by Dr Natale - failed 5-2021. Revision 6-2021 with issue (scrotal hematoma and infection). Dr. Ryan Terlecki revision 3-28-2022 (AMS700 CX 21cm with 1.5cm RTE). Cylinder failure at 18 months. 24cm AMS700 CX 11-29-2023.
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Re: Trimix..tissue damage?
I had a very painful erection that lasted for almost 4 hours, I injected the Phenylephrine and the erection went down, but two days later I developed a lateral deviation with a "dent" on the side of the Trimix injection, now 3 years later my penis shaft is narrower, left lateral deviation, slightly rotation...
If the erection is not painful then don't worry, but if is painful take Sudafed right away even if the erection is of 40 min, the danger is the pain!!!!, "Dr Nathan Papadeas" of Phoenix, AZ never warned me of anything!!!, now my damage is for life, for just one time!!!!
If the erection is not painful then don't worry, but if is painful take Sudafed right away even if the erection is of 40 min, the danger is the pain!!!!, "Dr Nathan Papadeas" of Phoenix, AZ never warned me of anything!!!, now my damage is for life, for just one time!!!!
I had a trauma 2 years ago, caused me narrowing, dent and shortening. PRP injections three months ago=worse narrowing, and worse ED. Now I only have two choices: impotent or implant. Born in 1975, in a relationship with girlfriend fir 4 years
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