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I get a great erection with Trimix and a cock and balls ring. About 50% of the time I wear my wife out and I cannot achieve an orgasm. Is this a side effect of Trimix? Today we went at it for 45 minutes off and on pardon the pun and while she had several orgasms after 45 minutes she said I can't take anymore pounding. She then tried to finish me off by hand and then mouth. No luck. I never had this problem with Viagra. This situation has only occurred since starting Trimix about two years ago.

Yeah, it can be an issue. Try to use the least juice needed to do the job.

Yes! I have had this problem more times than I can count. My wife has told many of her friends that I absolutely wear her ass out in the bedroom. I found this to be a problem with Trimix. Revaluate how much your using and see if coming down some might help. I just found this to be one of the problems with using this medication.

Have this discussion with your urologist. I'd be interested in hearing what he or she might say.

There is a whole thread on this issue which discusses the problem of no ejaculation when too much Trimix is used.
Look at viewtopic.php?f=22&t=10287.