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Question regarding alprostadil/mono mix strength??

Posted: Tue Mar 02, 2021 2:02 am
by kali64amd
hi, all

I’m just confuse about alprostadil strength, Beacause in india we are getting 500 mcg alprostadil inj and it says 2.5 mcg initial dose then 5 mcg and so on. So I’m bit confuse about it’s strength and how much it messure in units???

Has anybody have heard 500 mcg inj, you can google it alprostadil in india

Appreciate any input

thanks

Re: Question regarding alprostadil/mono mix strength??

Posted: Tue Mar 02, 2021 7:19 am
by wolfpacker
Is the 500mcg in a vial or a single injection? I'm using about 20mcg of alprostadil in each injection. Like you said, I started with 5mcg, which did almost nothing. Then 10, 15, and finally 20.

Re: Question regarding alprostadil/mono mix strength??

Posted: Tue Mar 02, 2021 1:33 pm
by bldoink
I'm not a medical professional of any kind. Anything I post is based on my own experiences, at best and hallucinations or delusions, at worst. Always ask your doctor and follow his/her advice. Internet forum advice is likely worth what you paid for it, or worse.

More information would be helpful.
What form is it in? Is it a dry powder or tablet that must be dissolved in saline? Is it already a liquid in a vial? Do you have a link to whatever it is?

Is this it?
https://www.indiamart.com/proddetail/alprostadil-injection-ip-21987985912.html

If it is I'm guessing it's one vial of one ml at 500mcg per ml in saline. If that's the case I think I'd be wanting some more vials and injection quality saline. I'd be diluting it, and being very careful and sterile in the process. I'd then freeze it as that is a fair amount and would likely go bad if not frozen.

Re: Question regarding alprostadil/mono mix strength??

Posted: Tue Mar 02, 2021 5:59 pm
by phallus
wolfpacker wrote:Is the 500mcg in a vial or a single injection? I'm using about 20mcg of alprostadil in each injection. Like you said, I started with 5mcg, which did almost nothing. Then 10, 15, and finally 20.

Just of curiosity, what is the reason for your ED? How long do 10 mcg vs 20 mcg keep you hard?

Re: Question regarding alprostadil/mono mix strength??

Posted: Tue Mar 02, 2021 10:49 pm
by wolfpacker
phallus wrote:
wolfpacker wrote:Is the 500mcg in a vial or a single injection? I'm using about 20mcg of alprostadil in each injection. Like you said, I started with 5mcg, which did almost nothing. Then 10, 15, and finally 20.

Just of curiosity, what is the reason for your ED? How long do 10 mcg vs 20 mcg keep you hard?


I have pretty bad veinous leak. I get great inflow blood, even without the injection, but it just doesn't stay and the erection deflates instantly. With the injection, it gets firmer but still not as hard as I would like. It stays that way for about 30 minutes or until I orgasm. I think I'm going to try trimix next and hope to get a better result than the 20mcg alprostadil.

Re: Question regarding alprostadil/mono mix strength??

Posted: Wed Mar 03, 2021 12:13 am
by kali64amd
bldoink wrote:I'm not a medical professional of any kind. Anything I post is based on my own experiences, at best and hallucinations or delusions, at worst. Always ask your doctor and follow his/her advice. Internet forum advice is likely worth what you paid for it, or worse.

More information would be helpful.
What form is it in? Is it a dry powder or tablet that must be dissolved in saline? Is it already a liquid in a vial? Do you have a link to whatever it is?

Is this it?
https://www.indiamart.com/proddetail/alprostadil-injection-ip-21987985912.html

If it is I'm guessing it's one vial of one ml at 500mcg per ml in saline. If that's the case I think I'd be wanting some more vials and injection quality saline. I'd be diluting it, and being very careful and sterile in the process. I'd then freeze it as that is a fair amount and would likely go bad if not frozen.


I'm not sure what form it come because I haven't received yet but i m bit confuse about its strength its 500mcg and I haven't seen that much high strength her.

My concern is how much unit should i start with?

has anyone have idea?

Re: Question regarding alprostadil/mono mix strength??

Posted: Wed Mar 03, 2021 2:55 am
by bldoink
I would hope you're under some sort of doctors supervision and will be provided instructions. You need to be under a doctors supervision.

I'm going to assume your alprostadil will be the same drug as what I use. My alprostadil is dispensed at 80mcg per ml. I'm currently using 14, u-100 insulin units as measured on a U-100 insulin syringe. My poor math skills seem to indicate my 14 units works out to be in the neighborhood of 11mcg of alprostadil. My non professional suggestion to a new user would be to start out at about 4 units of my 80mcg/ml mix. This would give a dose of a bit over 3mcg of alprostadil. In most cases I wouldn't expect such a dose to be sufficient but using caution when starting can save you from a priapism and a trip to the hospital. Your mix, if at 500mcg/ml would about 6 times as strong as my mix. I don't think it would be possible to measure out 3 to 4 mcg of alprostadil at that 500mcg/ml strength. I think I'd want to dilute a 500mcg/ml mix down to at least 100mcg/ml. That would make dosing much easier. If you want a 4mcg dose you would then draw up 4 units (.04ml). Additionally, the more diluted the mix the less it hurts when injecting. If I inject my mix quickly, even at 80mcg/ml, I will get pain. I have to inject slowly, that way I avoid pain. If you'll be injecting such small amounts you'll want syringes that only hold .3cc.
Find a good doctor!

Good luck.

All of the above is just speculation as I don't actually know what your mix is. Besides, I'm in no way qualified to give medical advice. You should definitely ask someone that is qualified to give medical advice.

Re: Question regarding alprostadil/mono mix strength??

Posted: Wed Mar 03, 2021 8:17 am
by wolfpacker
kali64amd wrote:
bldoink wrote:I'm not a medical professional of any kind. Anything I post is based on my own experiences, at best and hallucinations or delusions, at worst. Always ask your doctor and follow his/her advice. Internet forum advice is likely worth what you paid for it, or worse.

More information would be helpful.
What form is it in? Is it a dry powder or tablet that must be dissolved in saline? Is it already a liquid in a vial? Do you have a link to whatever it is?

Is this it?
https://www.indiamart.com/proddetail/alprostadil-injection-ip-21987985912.html

If it is I'm guessing it's one vial of one ml at 500mcg per ml in saline. If that's the case I think I'd be wanting some more vials and injection quality saline. I'd be diluting it, and being very careful and sterile in the process. I'd then freeze it as that is a fair amount and would likely go bad if not frozen.


I'm not sure what form it come because I haven't received yet but i m bit confuse about its strength its 500mcg and I haven't seen that much high strength her.

My concern is how much unit should i start with?

has anyone have idea?



Start with 5mcg, then 10, 15, 20

Re: Question regarding alprostadil/mono mix strength??

Posted: Wed Mar 03, 2021 11:59 pm
by kali64amd
bldoink wrote:I would hope you're under some sort of doctors supervision and will be provided instructions. You need to be under a doctors supervision.

I'm going to assume your alprostadil will be the same drug as what I use. My alprostadil is dispensed at 80mcg per ml. I'm currently using 14,as measured on a U-100 insulin syringe. My poor math skills seem to indicate my 14 units works out to be in the neighborhood of 11mcg of alprostadil. My non professional suggestion to a new user would be to start out at about 4 units of my 80mcg/ml mix. This would give a dose of a bit over 3mcg of alprostadil. In most cases I wouldn't expect such a dose to be sufficient but using caution when starting can save you from a priapism and a trip to the hospital. Your mix, if at 500mcg/ml would about 6 times as strong as my mix. I don't think it would be possible to measure out 3 to 4 mcg of alprostadil at that 500mcg/ml strength. I think I'd want to dilute a 500mcg/ml mix down to at least 100mcg/ml. That would make dosing much easier. If you want a 4mcg dose you would then draw up 4 units (.04ml). Additionally, the more diluted the mix the less it hurts when injecting. If I inject my mix quickly, even at 80mcg/ml, I will get pain. I have to inject slowly, that way I avoid pain. If you'll be injecting such small amounts you'll want syringes that only hold .3cc.
Find a good doctor!

Good luck.

All of the above is just speculation as I don't actually know what your mix is. Besides, I'm in no way qualified to give medical advice. You should definitely ask someone that is qualified to give medical advice.


@bldoink I really appreciate your help, its really help full So could you please answer couple of more questions?

1) As you know my strength is 500mcg so that mean I should diluted with 4ml saline right?
2) if i do this my starting dose should be 5 unit rt? or 10 bit confuse cuz my strength is 500mcg which is pretty high.
3) which syringe should i use u-100 insulin 100 units or u-100 insulin 30 unit syringe??


thanks

Re: Question regarding alprostadil/mono mix strength??

Posted: Thu Mar 04, 2021 3:00 pm
by bldoink
kali64amd wrote:@bldoink I really appreciate your help, its really help full So could you please answer couple of more questions?

Don't appreciate me too much. I don't know shit and you really need some solid advice from a professional. I'll try to give you my answers to your questions but let me restate my standard and accurate disclaimer:

I'm not a medical professional of any kind. Anything I post is based on my own experiences, at best and hallucinations and/or delusions at worst. Internet forum medical advice is likely worth what you paid for it, or worse. Always ask your doctor (I'll add and pharmacist) and follow his/her advice.

kali64amd wrote:1) As you know my strength is 500mcg so that mean I should diluted with 4ml saline right?

Yeah, I think you're correct but this is one I'd check with a pharmacist with. It should be an easy question for them.
kali64amd wrote:2) if i do this my starting dose should be 5 unit rt? or 10 bit confuse cuz my strength is 500mcg which is pretty high.

Undiluted and still at 500mcg/ml I wouldn't have any idea how to measure out and inject a small enough amount to start with. That would be what, 1 unit? Not possible!

Diluted to 100mcg/ml I'm thinking 4 or 5 units would be a reasonable start. Let me reiterate, you really need competent medical advice, which I'm not! As for diluting, I don't know what form you're getting this stuff in. If in liquid form I think I'd draw out and dilute 1/5 of it at a time into sterile vials and leave the remainder frozen.

Messing with injectionable drugs like this is some dangerous shit. There is a reason only certain pharmacy labs are certified to do this work. You don't want to be injecting bacteria into your dick. If you proceed with this make damned sure you get some solid professional advice on how to do it safely, which you can't possibly get from me.
kali64amd wrote:3) which syringe should i use u-100 insulin 100 units or u-100 insulin 30 unit syringe??

If you dilute to 100mcg/ml then, IMHO, U-100 30 unit is the only way to go. As you titrate (work your way probably up in determining dose) stay with the 30 unit syringes as long as you stay below 30 units. A 100 unit syringe (1ml) would be difficult to measure or inject accurately.

kali64amd wrote:thanks

Don't thank me please. You really need competent professional medical advice. Please get it somewhere. What I post is most definitely NOT competent medical advice and is likely just dangerous bad advice.

Good luck.