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So I successfully self injected 10mcg of Edex for the first time today as a test. The good news is that I had a really strong erection for about 1 hour and am quite happy about that. However the erection was painful. It was like a numbing pain that pretty much lasted the duration of my erection. The pain was fairly intense. I don't think I can even ejaculate under such circumstances. Has anyone experienced something like this? I guess I should probably switch to Trimix?

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So if I inject a smaller dose of Edex, that might lessen the pain but that would also lessen the length of time of the erection? Also would I experience a similar pain with Trimix? When I was injected with Trimix at the doctor's office, I did not experience the same level of pain. But the erection was also not as strong.

dxchase70 wrote:So if I inject a smaller dose of Edex, that might lessen the pain but that would also lessen the length of time of the erection? Also would I experience a similar pain with Trimix? When I was injected with Trimix at the doctor's office, I did not experience the same level of pain. But the erection was also not as strong.

You'll get a stronger erection with less pain with Trimix, however the tradeoff is that Trimix is more likely to damage your penis and create scar tissue inside it, and can even give you a curve or shortening from Peyronie's disease.

The pain is likely from the prostaglandin. Some of us (me included) get ache from prostaglandins.

Two options occur to me:

Try a smaller dose and see if you get a firm erection without the ache.

Try BiMix. It contains papaverine and phentolamine. Others have suggested TriMix which is Papaverine, phentolamine, AND prostaglandins. Try BiMix first as it seems that the problem may be the prostaglandins. Don’t switch to another med with prostaglandins in it. Try BiMix first.

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Yeah I personally had really bad pain at the start. Now the pain is much much less. I think the more you inject the more tolerance you build or something. Don’t really think about it anymore.

Thanks again guys for all the advice. There quite a few things to consider here but it seems like the prudent thing to do for now is to continue testing with Edex and to try and find that sweet spot as bldoink mentioned.