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Is there some sort of chart or formula for converting how much Tri-Mix (30/1/10 mcg Alprostadil) is somewhat equivalent to Mono-mix? Yes, I realize it will be trial and error to an extent.

My doc was going to prescribe .03 ccs (3 units) of Tri-Mix 105 (30/1/10) b/c at .1 cc it gave me a priapism.

However, after reading about the scarring/fibrosis potential of Tri-Mix (mostly due to Papavarine from what I read), I want to switch to a Mono-Mix, but as yet haven't found a new doc I trust to dose me correctly (current doc is adamant that Tri-Mix is what he'll use and has refused Mono-Mix as an option).

Apparently, there's Mono-mix in 40, 80 and 150 mcg.

Anyone know which dosage would likely be required?

I'm not a medical professional of any kind. Anything I post is based on my own experiences at best and hallucinations and/or delusions at worst. Internet forum advice is likely worth what you paid for it or worse. Always ask your doctor and follow his/her advice.

No, no chart. I'd be afraid to try to meter out a small enough batch of 40mcg/ml alprostadil for you at your sensitivity. In your case I'd want my first batch to be 10mcg/ml and try maybe 5 units (.05cc) at the most. You can always get a stronger batch on the next order.

Good luck.

bldoink wrote:I'm not a medical professional of any kind. Anything I post is based on my own experiences at best and hallucinations and/or delusions at worst. Internet forum advice is likely worth what you paid for it or worse. Always ask your doctor and follow his/her advice.

No, no chart. I'd be afraid to try to meter out a small enough batch of 40mcg/ml alprostadil for you at your sensitivity. In your case I'd want my first batch to be 10mcg/ml and try maybe 5 units (.05cc) at the most. You can always get a stronger batch on the next order.

Good luck.

Yeah, without knowing wtf I'm talking about as a mere layperson....40 mcg of Mono-mix Alprostadil vs. the 10 mcg of Alprostadil in Tri-Mix 105 (30/1/10) may be precisely why the doctor doesn't want to use Mono-mix. Though I'd think a good pharmacy could just do a 10 mcg Mono-mix....but maybe I'm way off base there too.

So if he was thinking .03 cc of Trimix 105, that would equate to 30 mcg of Alprostadil in that dose. From what I've read, Mono-mix will require more Alprostadil than Trimix to give the same erection quality. I'm guessing that only injecting .01cc of 40mcg/ml Mono-mix isn't really practical, but as you said, if I could get a 10 or even 20 mcg/ml batch....It could conceivably work...I'd just have to adjust how many units I'm injecting.

Thanks so much for explaining. It's very much appreciated.

Sean762 wrote:.....Though I'd think a good pharmacy could just do a 10 mcg Mono-mix....but maybe I'm way off base there too.

A good compounding pharmacy should be able to mix up whatever the doctor prescribes. Mine can but they only ship within FL.

Sean762 wrote:So if he was thinking .03 cc of Trimix 105, that would equate to 30 mcg of Alprostadil in that dose. From what I've read, Mono-mix will require more Alprostadil than Trimix to give the same erection quality.

I'm thinking the Trimix 105 is 10mcg of alprostadil not 30. Yes you will likely need more alprostadil in a monomix than the alprostadil in a trimix but alprostadil is the heavy hitter of the mix.

Sean762 wrote:I'm guessing that only injecting .01cc of 40mcg/ml Mono-mix isn't really practical, but as you said, if I could get a 10 or even 20 mcg/ml batch....It could conceivably work...I'd just have to adjust how many units I'm injecting.

You want a mix where you're at least using 5 units and preferably at least 8 or so. It's just too hard to meter smaller doses and a small error would make a big difference. It sounds like you are very sensitive to the drugs so I think I'd want to start at the lower potency. You don't want another priapism.

bldoink wrote:A good compounding pharmacy should be able to mix up whatever the doctor prescribes. Mine can but they only ship within FL.

Thanks for confirming. Good info.

Sean762 wrote:So if he was thinking .03 cc of Trimix 105, that would equate to 30 mcg of Alprostadil in that dose. From what I've read, Mono-mix will require more Alprostadil than Trimix to give the same erection quality.

bldoink wrote:I'm thinking the Trimix 105 is 10mcg of alprostadil not 30. Yes you will likely need more alprostadil in a monomix than the alprostadil in a trimix but alprostadil is the heavy hitter of the mix.

You're correct that Trimix 105 is 10mcg/ml Alprostadil....but the dose was 3 ml which is how I arrived at 30mcg total.

bldoink wrote:You want a mix where you're at least using 5 units and preferably at least 8 or so. It's just too hard to meter smaller doses and a small error would make a big difference. It sounds like you are very sensitive to the drugs so I think I'd want to start at the lower potency. You don't want another priapism.

Agreed that it would be harder to meter a small dose like this and again it makes me question my current urologist's familiarity with injections considering he was recommending a dose of 3 units of Trimix 105.

For the record, I do think I have a potentially heavy psychogenic component to my ED, but I may also have unrealistic expectations for EQ considering how hard was 'hard' for me before ED set in. I've read a lot of guys conveying their injection induced erection was the hardest erection of their lives....my 1st (and only so far that resulted in priapism) was pretty normal for me (other than the head didn't inflate as usual). I wonder if it's just unrealistic to expect that level of hardness as one ages. I am hopeful injections might help ease that psychological component and maybe I'll be able to wean off them, if my problem isn't at all organic.