I've been using trimix for about 3 years now and recently it's effectiveness has diminished. It's only giving me about 60% of what it did previously.
My doctor increased the strength several times but that didn't help much. My prescription is very strong now (60/30/3) and I inject 75 units.
I was looking through these forums for possible ideas/solutions and I came across two which I'm hoping could help:
1) From the beginning, I've always used a 31 gauge, 5/16 inch needle. but I saw that someone said that they'd always used a 29 gauge, 1/2 inch needle and then they tried a 31 gauge, 5/16 inch needle; and the trimix was ineffective with the 31 gauge, 5/16 inch needle. This happened a few times and then he returned to using the 29 gauge, 1/2 inch needle; at which point the injections began working well again.
Is there any reason to believe that switching from a 31 gauge, 5/16 inch needle to a 29 gauge, 1/2 inch needle could make my trimix injections effective again?
2) I read someone saying that they use a constricting ring at the base of their penis either while or right after injecting. Could this keep the injected trimix from leaving the penis? and as a result, allow it to be more effective?
Thanks in advance
Two possible solutions for ineffective trimix injections?
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Re: Two possible solutions for ineffective trimix injections?
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Last edited by bldoink on Tue Aug 05, 2025 8:53 pm, edited 1 time in total.
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Re: Two possible solutions for ineffective trimix injections?
CoconutWater27 wrote:Is there any reason to believe that switching from a 31 gauge, 5/16 inch needle to a 29 gauge, 1/2 inch needle could make my trimix injections effective again?
2) I read someone saying that they use a constricting ring at the base of their penis either while or right after injecting. Could this keep the injected trimix from leaving the penis? and as a result, allow it to be more effective?
I don't think the length or size will make the Trimix more or less effective. However, a 5/16 length needle may cause more misses because it may not fully penetrate the corpora cavernosa (erectile chamber).
I have used a cock ring for years long before doing injections. For me the cock ring makes my penis 10-15% harder with Trimix.
I put the cock ring on just before injecting. Which helps keep the Trimix in the penis.
I leave it on until after the sex act is finished. Our sessions are fairly short at 20-30 minutes, after which I remove the cock ring on.
Since starting the use of Trimix and using the cock ring I've had to cut back on the dosage. I'm pretty sure it's partially due to cock ring.
Your result may vary. Although I've heard from a number of trimix users who say it also helps them.
Struggled with ED/PE for years.
Started using Trimix in May 2022 with very good results.
Started using Trimix in May 2022 with very good results.
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Re: Two possible solutions for ineffective trimix injections?
bldoink wrote:Don't expect success with the first rings you try. Expect rejects until you find what works best for you. I can suggest the ones I use if you like but you may find others work better for you.
Thanks for responding. and yes please suggest the ones you use. I suspect a lot of the trimix is escaping since I'm injecting 75 units. I'm really hoping this can help keep it from doing so
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Re: Two possible solutions for ineffective trimix injections?
sogwap wrote:CoconutWater27 wrote:Is there any reason to believe that switching from a 31 gauge, 5/16 inch needle to a 29 gauge, 1/2 inch needle could make my trimix injections effective again?
2) I read someone saying that they use a constricting ring at the base of their penis either while or right after injecting. Could this keep the injected trimix from leaving the penis? and as a result, allow it to be more effective?
I don't think the length or size will make the Trimix more or less effective. However, a 5/16 length needle may cause more misses because it may not fully penetrate the corpora cavernosa (erectile chamber).
I have used a cock ring for years long before doing injections. For me the cock ring makes my penis 10-15% harder with Trimix.
I put the cock ring on just before injecting. Which helps keep the Trimix in the penis.
I leave it on until after the sex act is finished. Our sessions are fairly short at 20-30 minutes, after which I remove the cock ring on.
Since starting the use of Trimix and using the cock ring I've had to cut back on the dosage. I'm pretty sure it's partially due to cock ring.
Your result may vary. Although I've heard from a number of trimix users who say it also helps them.
Thanks for your response. A 10-15% difference would be great. I'm definitely going to give it a try
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Re: Two possible solutions for ineffective trimix injections?
...
Last edited by bldoink on Tue Aug 05, 2025 8:54 pm, edited 1 time in total.
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Re: Two possible solutions for ineffective trimix injections?
bldoink wrote:CoconutWater27, PM sent.
Reading it now. Thanks
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Re: Two possible solutions for ineffective trimix injections?
Here's the Cock Ring I use. It's available at Walmart, Amazon, and at my local drugstore.
https://www.amazon.ca/Durex-Pleasure-In ... B01BGWL6K8
Google it: Durex Pleasure Ring
It is made from silicone (stretchable) and seems to be well-made and lasts several months before needing to be replaced.
https://www.amazon.ca/Durex-Pleasure-In ... B01BGWL6K8
Google it: Durex Pleasure Ring
It is made from silicone (stretchable) and seems to be well-made and lasts several months before needing to be replaced.
Struggled with ED/PE for years.
Started using Trimix in May 2022 with very good results.
Started using Trimix in May 2022 with very good results.
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- Posts: 7
- Joined: Tue Dec 13, 2022 12:33 am
Re: Two possible solutions for ineffective trimix injections?
sogwap wrote:Here's the Cock Ring I use. It's available at Walmart, Amazon, and at my local drugstore.
https://www.amazon.ca/Durex-Pleasure-In ... B01BGWL6K8
Google it: Durex Pleasure Ring
It is made from silicone (stretchable) and seems to be well-made and lasts several months before needing to be replaced.
Thanks
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