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Good morning - I have a cold and would like to take Sudafed, but something in that compound is said to effect TRIMEX. Does anyone know what the ingredient is? - Mike

5-6 doses of Sudafed will make a Trimix induced erection go down. Probably make you sleepy too.
I don't think taking a dose as recommended will affect anything.

The half-life of pseudoephedrine (the main ingredient in Sudafed) is between 5 and 8 hours.

Unless you are planning to inject (trimix) while having a cold, doubtful it will have much effect on Trimix.