FrankTalk.org

Do the majority of men on injections develop scarring and Peyronies after some years of usage as it is widely depicted here?
Or are the results biased because most of men who have problems go on to complain in these forums?
Is there any peer reviewed study on fibrosis after long term injections? How much is really the risk?

There seems to be only one study with long-term follow-up:
https://pubmed.ncbi.nlm.nih.gov/31477852/

It’s retrospective and suffers from selection bias but it shows that some patients were able to use it for 10-20 years. Other than that there were some studies in the 1980’s but only with follow-up of around one year. But I don’t think there’s any high-quality evidence out there.

There’s also quite a few franktalk members who have used 1000 injections and a few have used them for 20 years. Some of them are collected in the “injections leaderboard” thread:
viewtopic.php?f=5&t=18622

The thread only includes people who responded to it, and there’s a few more users on the site who have used long-term, (a decade or 1000 injections).

If you are using Invicorp or other medications where it is supplied in glass ampoules then I would highly recommend throwing the blunt draw up needles away and buy BD filter needles as there is always a certain amount of glass particles that end up in the solution otherwise.
The idea of injecting glass particles into your penis... I can't help thinking this is likely to cause plaques.

Most countries Nursing/medical guidelines recommend using filter needles for draw up from glass ampoules that you have to break open. There was a good photo showing how much glass is dispersed when they are opened, cant find it now but was in one of the research papers I found. I'll try and find it later

I've used injections for like 3 years now. Like 3-4 times a week and sometimes several times in a day.
No scarring, but:
- Always alternate sides
- Use a 31 gauge needle
- Use a VED every day
- Do traction

It depends on the guy, some guys inject Trimix for 30 years with no problems and some guys get bad damaged right away