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Can a MD prescribe Trimix?

Posted: Thu Apr 06, 2023 4:46 pm
by Steve_ED
My urologist that just prescribed Trimix for me retired. There is no one at that office that can prescribe a stronger formula for me to try. There are two other offices around town that are taking his patients, but they are currently overwhelmed. I was told it could be next week or it could be several months before I can get an appointment. The physicians assistant that gave me my instructions told me to go to .80 on this current formula and call her back if that did not work. Turns out she is also gone now. I have called my medical doctor and left a message with his nurse. I don’t know if it something that only a urologist can prescribe or a MD can prescribe? Just wondering if anyone has had a MD prescribe it for you?

Thanks …

Re: Can a MD prescribe Trimix?

Posted: Thu Apr 06, 2023 4:57 pm
by Flounder
Yes, any MD can legally prescribe it for you.
Weather he or she is comfortable / willing to do so is another thing.

Re: Can a MD prescribe Trimix?

Posted: Thu Apr 06, 2023 9:12 pm
by ScrewedbyDoctors
Nurses, Phisician assistants and Naturepath "Doctors" can prescribe Trimix

Re: Can a MD prescribe Trimix?

Posted: Sat Apr 08, 2023 6:51 pm
by Steve_ED
Thanks …. I have left a message with my MD’s nurse.

Re: Can a MD prescribe Trimix?

Posted: Sat Apr 08, 2023 9:32 pm
by bldoink
Steve, I've had 3 primary care doctors prescribe my mono-mix for me. None of them knew much about it. I had to educate all three.

I doubt you'll have much success calling in and asking for a script. I'd advise seeing your Primary, GP or whatever you call him/her in person and be prepared to educate them. Having an old script in hand would probably help. Perhaps determining what pharmacy you'll be using and have a printout of their mix offerings (if available) and maybe a suggestion from the pharmacist as to your next mix.

Be able to explain how you lost your previous prescriber. Also explain your current delay in getting a new Uro. You might mention that most of them aren't really up on the topic as they specialize in other issues. Be able to explain the drug and process and why you need it. If you're confident you can offer to demonstrate if they seem interested.

A lot of medical professionals have egos so you need to use care in explaining and making your pitch. You need to show confidence so your pitch will be more believable but you need to also show deference to them so that they don't feel offended by your educating them.

Also note that in my amateur very NONmedical professional opinion, if you're using 80units of mix, you need a mix at least twice as potent. (I use a potent mix that allows me to use about 16 units. A volume of mix I consider about ideal) Perhaps, if you stated your current mix (amounts of each drug per ml), an experienced tri-mix user might be able to suggest a new stronger mix. My experience is with alprostadil (PGE-1) mono-mix so I'm not the best person to suggest mixes for you. If you do get a much stronger mix you'll have to greatly reduce your starting dose and titrate up from there. You'll need to clearly and confidently explain that to your doctor so they can feel confident you won't screw yourself up.

Good luck!

Re: Can a MD prescribe Trimix?

Posted: Sat Apr 08, 2023 11:20 pm
by Steve_ED
Thank you. This is my first try with Trimix. It did occur to me to call the pharmacist and ask them their recommendation for my next prescription. I believe that this is a pretty weak formula, it is TRIPLE MIX INJ (IJPC) 15MG/0.5MG/10MCG/ML. This is a copy from my label.

Re: Can a MD prescribe Trimix?

Posted: Sun Apr 09, 2023 12:59 am
by bldoink
Yeah, that's a very weak mix.

Re: Can a MD prescribe Trimix?

Posted: Sun Apr 09, 2023 2:05 am
by ThatTallGuy
Yes, what bldoink said about educating your primary Care Doctor, but don't be surprised if he immediately tells you to see a Urologist to get an RX.
I lost my Urologist too and asked my doctor if he could help and he did because he already knew my history with the meds for many years, but don't be surprised if he says he can't help you.

Re: Can a MD prescribe Trimix?

Posted: Sun Apr 09, 2023 7:07 am
by Hillywilly
Steve_ED wrote:My urologist that just prescribed Trimix for me retired. There is no one at that office that can prescribe a stronger formula for me to try. There are two other offices around town that are taking his patients, but they are currently overwhelmed. I was told it could be next week or it could be several months before I can get an appointment. The physicians assistant that gave me my instructions told me to go to .80 on this current formula and call her back if that did not work. Turns out she is also gone now. I have called my medical doctor and left a message with his nurse. I don’t know if it something that only a urologist can prescribe or a MD can prescribe? Just wondering if anyone has had a MD prescribe it for you?

Thanks …


I would recommend against Trimix. Personally I used it and sex was great with it but I didn't realize it was causing further damage to my penis if I had I would have just stuck with the pills or penile implant. But don't take my word for it here is what WORLD CLASS SURGEON Dr. EID has to say on the compound:

"Thank you for your post.
It gives me the opportunity to share information and my personal opinion on some of the treatment options that you have used. Trimix is composed of 3 medications; papaverine, phentolamine and alprostadil. The only substance that is approved by the FDA for penile self injection is alprostadil (Caverject or Edex) which is available by prescription at your local drugstore. Neither papaverine nor phentolamine are approved by the FDA for penile self injection. In the late 80's and early 90's, Elli Lilly the company that used to dispense papaverine went as far as to document on the bottle that papaverine is contraindicated for penile self injection. Papaverine will scar and deform the cavernosal muscle tissue over time. This causes the muscle to become fibrosed and scarred; which typically will cause the need for a dose escalation and subsequently an acceleration and increase in penile damage. Papaverine also binds irreversibly to the receptors on the surface of muscle cells and results in an abnormally firm erection and a much greater risk in causing priapism that is more difficult to pharmacologically reverse."

Re: Can a MD prescribe Trimix?

Posted: Sun Apr 09, 2023 7:29 am
by bldoink
The above post is one reason I stick with alprostadil mono-mix. That and the mono-mix works well for me. I started on Edex but my insurance didn't cover it and I couldn't afford it on my own. I get my alprostadil mono-mix from a somewhat local compounding pharmacy for a fraction of the cost of Edex and I actually like the compounded mix better. I get a stronger mix and I never liked the Edex proprietary cartridges, well except for it's excellent unrefrigerated shelf life. The compounded mono-mix needs to be kept frozen. Unfortunately not everyone can tolerate straight alprostadil.