PT-141 and trimix

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sirgawain
Posts: 86
Joined: Sat Feb 13, 2021 8:44 pm
Location: Bellevue, WA

PT-141 and trimix

Postby sirgawain » Wed Aug 09, 2023 1:16 pm

I am not sure why, but every time I have tried this combo, the trimix fails entirely. I’ll get hard, but it goes away a lot faster than it should.

Any ideas of what could cause that?
57 years old, artificial heart valve. TRT started May, 2020. ED/libido issues never fixed by TRT. Not super responsive to viagra/cialis. Started Trimix 2/2021. 20/7.5/.25 mix.

GoodWood
Posts: 970
Joined: Sun Jun 16, 2019 1:07 pm

Re: PT-141 and trimix

Postby GoodWood » Wed Aug 09, 2023 3:13 pm

Hmmm…. I’ve used this combo several times and not had any problems.

And Trimix is foolproof for you otherwise?
56yo, NYC. ED started at 40. Pills first, then shots for nearly 10 years. 24cm Coloplast Titan w/classic pump implanted by Dr Eid 3/25/2025.

sirgawain
Posts: 86
Joined: Sat Feb 13, 2021 8:44 pm
Location: Bellevue, WA

Re: PT-141 and trimix

Postby sirgawain » Wed Aug 09, 2023 3:20 pm

Yes, been using trimix for over a year. It’s only recently that I have tried pt-141. I wonder if it’s because I’m injecting more chubbed up? I wait until about 6-8 hours after I take the pt-141, injecting what I normally do. Then I have it die in about half the time I’m used to. Twice now. Trying again today (I wait a long time between pt-141 shots and worried a bit as we are on vacation and she is hoping for a good session today. :)
57 years old, artificial heart valve. TRT started May, 2020. ED/libido issues never fixed by TRT. Not super responsive to viagra/cialis. Started Trimix 2/2021. 20/7.5/.25 mix.

Pumpkinman
Posts: 184
Joined: Fri Nov 04, 2022 2:32 pm

Re: PT-141 and trimix

Postby Pumpkinman » Wed Aug 09, 2023 3:27 pm

sirgawain wrote:Yes, been using trimix for over a year. It’s only recently that I have tried pt-141. I wonder if it’s because I’m injecting more chubbed up? I wait until about 6-8 hours after I take the pt-141, injecting what I normally do. Then I have it die in about half the time I’m used to. Twice now. Trying again today (I wait a long time between pt-141 shots and worried a bit as we are on vacation and she is hoping for a good session today. :)


It's most likely due to the fact that you're already chubbed up and not getting the needle all the way in the Corpus Cavernosum, so make sure you push the needle really deep to insure the medicine in.

sirgawain
Posts: 86
Joined: Sat Feb 13, 2021 8:44 pm
Location: Bellevue, WA

Re: PT-141 and trimix

Postby sirgawain » Thu Aug 10, 2023 2:09 am

Okay well it was a multiple failure on all fronts today. My wife and I both did it and each got nauseous, which was a new feature. Then, about 2.5 hours in, the 75% boner arrived and didn’t leave for hours. When it peaked and I was at enough hardness to have sex, she was still not feeling 100%, so it faded back down to 75%. I then injected. I use a 5/16 needle and when chubbed, it might not be enough to get all the way in there. I felt like I pierced, but it had no effect. So we had to have non intercourse sex.

I think our experimentation with pt-141 is over. And I should carry some longer needles.
57 years old, artificial heart valve. TRT started May, 2020. ED/libido issues never fixed by TRT. Not super responsive to viagra/cialis. Started Trimix 2/2021. 20/7.5/.25 mix.

CanGetItUpButNotOff
Posts: 240
Joined: Mon Sep 20, 2021 1:34 pm

Re: PT-141 and trimix

Postby CanGetItUpButNotOff » Fri Nov 29, 2024 1:35 pm

I'm (more than) a little late to this thread, but I wonder if combining PT-141 and TriMix is a recipe for priapism? Since the former works on the central nervous system and the latter is a vasodilator, it seems like they might not compound the effect.
Born 1954. Diabetes, hypertension and atherosclerosis. Sildenafil is iffy. Tri-Mix (30/3/20 Pap/Phen/PGE1) a godsend pending long-term efficacy. Daily Cialis. Tried LiESWT, Botox, PT-141, Eroxon, QST, DUS, Vertica, cabergoline, psychotherapy+hypnotherapy.

scharff
Posts: 70
Joined: Wed Aug 23, 2023 8:50 am

Re: PT-141 and trimix

Postby scharff » Sun Dec 01, 2024 7:03 am

I've tried using it this way too. The PT ealier in the day and then the Trimix before sex. I didn't notice much of a difference in my erection but I was very stimulated and she was too. She masturbated early on and I gave her oral again before I did the Trimix. In the end, I just couldn't take the naseous feelings from the PT 141. But it was fun for a while.

CanGetItUpButNotOff
Posts: 240
Joined: Mon Sep 20, 2021 1:34 pm

Re: PT-141 and trimix

Postby CanGetItUpButNotOff » Sun Dec 01, 2024 8:33 am

I first became interested in PT-141 because of studies that showed it helped with orgasm. If those studies are valid, then I'd be interested in combining PT-141 with Trimix to get the orgasm benefits with the erection and no priapism.
Born 1954. Diabetes, hypertension and atherosclerosis. Sildenafil is iffy. Tri-Mix (30/3/20 Pap/Phen/PGE1) a godsend pending long-term efficacy. Daily Cialis. Tried LiESWT, Botox, PT-141, Eroxon, QST, DUS, Vertica, cabergoline, psychotherapy+hypnotherapy.


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