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I am not sure why, but every time I have tried this combo, the trimix fails entirely. I’ll get hard, but it goes away a lot faster than it should.

Any ideas of what could cause that?

Hmmm…. I’ve used this combo several times and not had any problems.

And Trimix is foolproof for you otherwise?

Yes, been using trimix for over a year. It’s only recently that I have tried pt-141. I wonder if it’s because I’m injecting more chubbed up? I wait until about 6-8 hours after I take the pt-141, injecting what I normally do. Then I have it die in about half the time I’m used to. Twice now. Trying again today (I wait a long time between pt-141 shots and worried a bit as we are on vacation and she is hoping for a good session today.

sirgawain wrote:Yes, been using trimix for over a year. It’s only recently that I have tried pt-141. I wonder if it’s because I’m injecting more chubbed up? I wait until about 6-8 hours after I take the pt-141, injecting what I normally do. Then I have it die in about half the time I’m used to. Twice now. Trying again today (I wait a long time between pt-141 shots and worried a bit as we are on vacation and she is hoping for a good session today.

It's most likely due to the fact that you're already chubbed up and not getting the needle all the way in the Corpus Cavernosum, so make sure you push the needle really deep to insure the medicine in.

Okay well it was a multiple failure on all fronts today. My wife and I both did it and each got nauseous, which was a new feature. Then, about 2.5 hours in, the 75% boner arrived and didn’t leave for hours. When it peaked and I was at enough hardness to have sex, she was still not feeling 100%, so it faded back down to 75%. I then injected. I use a 5/16 needle and when chubbed, it might not be enough to get all the way in there. I felt like I pierced, but it had no effect. So we had to have non intercourse sex.

I think our experimentation with pt-141 is over. And I should carry some longer needles.

I'm (more than) a little late to this thread, but I wonder if combining PT-141 and TriMix is a recipe for priapism? Since the former works on the central nervous system and the latter is a vasodilator, it seems like they might not compound the effect.

I've tried using it this way too. The PT ealier in the day and then the Trimix before sex. I didn't notice much of a difference in my erection but I was very stimulated and she was too. She masturbated early on and I gave her oral again before I did the Trimix. In the end, I just couldn't take the naseous feelings from the PT 141. But it was fun for a while.

I first became interested in PT-141 because of studies that showed it helped with orgasm. If those studies are valid, then I'd be interested in combining PT-141 with Trimix to get the orgasm benefits with the erection and no priapism.