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crystallization with frozen TriMix
Posted: Wed Jan 14, 2015 8:14 am
by newbie1
I have a bottle of TriMix about 1 month frozen (since day compounded) and today after thawing out I noticed some clear crystals at bottom of the bottle. Solution is still clear. Wont dissolve or disappear even with shaking.
Is this normal?
What could have caused it?
Re: crystallization with frozen TriMix
Posted: Wed Jan 14, 2015 10:37 pm
by JimStars
NB,
My Bi-Mix supplier says, at least for Bimix (not Trimix), that it can be stored in a cool but not refigerator cold place -- otherwise it can crystallize out.
Papaverine -- at 30mg per ml -- is a lot of product to have dissolve in such a small amount of liquid -- hence it can come out. I have a vial of Bi-Mix that was only refigerated and it did precipitate out and right now has a big single crystal floating around -- the only way to dissolve is to bathe the whole vial using some warm or hot water. I am not sure if PGE-1 will degrade if warmed up only for a short amount of time in order to get your crystals to redissolve. Probably not? Hard to say or even harder to tell when using it.
But try warming up .. swirling etc. And I suppose no more freezing for you.
J
Re: crystallization with frozen TriMix
Posted: Sun Jan 25, 2015 11:27 am
by spanzo
you really want to store the trimix at around refrigerator temps. like 35 to 40 degrees. room temp and it loses strength after a week, 60 degrees 2 weeks, 40 degrees and it is 6 months. there is a paper somewhere on it, I will try to find it.
opinions vary on if you can freeze it, my doctor said its ok, my compounding center said "no way"