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I seem to have gotten conflicting information about whether the potential for scarring and fibrosis is due to the trauma from the actual injection, the medication that goes into your penis, or the resulting long erection that some have that can go over 2 hours. Does anyone have any clear information on this?

This matters because for those who have an unsuccessful injection, you can try again soon after more regularly if it does not contribute to potential penile scarring as much as a successful injection does.

Thanks!
John

Just a guess, but I'd bet on needle trauma.

I've been seeing a specialist in Atlanta for three months for Peyronies disease. It's a 12 hour round-trip drive every two weeks, but his reputation for treating Peyronies is very good. After five of the recommended twelve treatments, I've seen the bend in my penis go from over 30 degrees to about 20.

I mention this because it's this doctor's opinion that injecting can cause the development of scar tissue, which is the cause of Peyronies. Given his experience, I give a lot of weight to what he has to say. He doesn't say that it will cause scar tissue to develop, but that it can cause it. In my case, the scar tissue was the result of an injury, although there's scar tissue in areas that were not injured, but where I inject.

I've lost an inch in length because of scar tissue. I'm going to ask him about Trimix gel or ED meds other than injections.

Just FYI.

bt,

I am almost up to 1000 injections now and have no signs of fibrosis or anything.

AND inject in a small area .. like .5" diameter all the time over and over .. not moving hardly from the same spot (on either side).

Hey, what works, works, yah?

It is my opinion, backed by no medical citations or anything, that fibrosis, when it happens, is just caused by a particularly sensitive/active immune system that detects SOMETHING there at the injection area, can't find what, so it produces fibrosis as a way of sealing off whatever might be there.

So .. tell your immune system to chill and Be Happy ...

J

Yeah I am just worried that sometimes I feel a knot where the injection took place for a couple days after the injection - but it basically goes away after a couple days. Wondering if that is normal or if it is the beginning of more serious fibrosis/scarring...

I quite often (about 50%) feel a knot after injecting for a day or so. I believe it is due it injured tissue or possibly irritation of a nerve ending. However, after three years, no sign of fibrosis.