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Hey crew - this is a long post - suitable for "techies" like me.

I've been experimenting with various doses of Trimix over the past couple years. I have not yet found a mix that works well (erection wise) without causing an ache about 20-30 minutes after the injection. While just about all of the scientific literature I've reviewed says the cause of the aching is due to the PGE-1, my own results seem to point in the other direction. My question is -- does anyone else have some experience with dosage vs aching? If you respond, please be sure to list your mix vs. your dosage.

My original mix was: --- 10, 30, 0.5 (PGE-1, Papaverine, Phentolamine), at a dose of 0.20ml (20 units) -- and that usually (erection wise - in the beginning) worked, but it caused some aching.

I went from there to -- 8, 30, 1.0, and then 5, 30, 1.5, on the premise that the PGE-1 was causing the aching. The erection quality diminished, but the aching did not, leading me to believe that the ache was more due to the Papa and the Phento.

The last mix required a higher doses to get a usable erection. The last mix, (5, 30, 1.5) at double the dosage (40 units) caused more aching then the first two. Considering the PGE-1 level at 40 units was the same as the first mix, it seems the aching was again, more initiated by either the increased Papa (doubled) or Phento (increased sixfold) from the dosage of the first mix.

I have since moved up to a mix of 20, 30, 2.0. A 20 unit dose works pretty well but the aching is still an issue. I typically find the aching does not begin until well into sex play. Actually seems like all is fine for about 20 minutes or so, but then the aching starts. At a dose of 22 units, (a 10% increase) the aching is sometimes so bad that I am physically ready to quit, even though I'm still mentally charged to continue.

Finally, I note that rigidness is not as great as it was 2 years ago which I assume is due to a bit of desensitization of my body to the PGE-1. According to my research rigidness is mostly due to the PGE-1 and duration to the Phento. Duration is not an issue. I am typically 80% herd after 2 hours, sometimes longer, but never less than an 1.5 hrs.

I was looking around to get a mix of 40, 30, 1 or even eliminate the papa and phento completely, and see what the results are with only the PGE-1, so, ............ I'm seeking anyone with similar experiences to share their results so I can get reference points other than myself.

Several pharmacies offer stronger mixes, but they all seem to increase all the chemicals proportionally. None seem to make a mix like the above with a high PGE-1 level and lower Papa and Phento. If anyone knows of one, please post.

Big

Here is my 2 cents.....

My mix is 20/2/30 (PGE1/Phemto/Papa)

I use about 15 units and it works well.
Yes, get the ache. Espiecially when new. But in the fridge after a few weeks it gets less potent and less ache. Still works pretty good.
Not sure which of the three looses potency the most, but probably has something to do with it.

Also, I recently tried Caverject. It has no PGE1 in it, and I used the 20ml which is the highest. I did not get a full erection, it took 30 to 45 minutes to work, and it ached worst than my trimix. So, I know the ache in the Caverject is not from PGE1 since there is none.
I believe the active ingredient in Caverject is alprostadil not that it helps.

Anyway, I am also interested in opinions on this. My pharmacy does custom which mine is. I can tweak it any way I like. So if we figure out what causes the ache, then I will decrease that ingredient and see how it goes.

Great topic

TreeTop,

Also, I recently tried Caverject. It has no PGE1 in it, and I used the 20ml (YOU MEAN 20mcg) which is the highest. I did not get a full erection, it took 30 to 45 minutes to work, and it ached worst than my trimix. So, I know the ache in the Caverject is not from PGE1 since there is none.

Yes the Caverject SYSTEM really is all PGE-1 (freeze dried version I think -- or liquid ampules).
And yes everyone calls it Caverject -- but is the same as PGE-1 (which is also trade named Alprostadil in the US and other countries -- but has other trade names too).

So all the ache is from PGE-1 in that shot - and 20mcg -- if you took the whole shot -- is quite a lot of PGE-1 considering Trimix at 20mcg/ml you might only need 10/15/20/30 units which means the total PGE-1 delivered is from 2mcg to 7mcg per shot. SO that is why Caverject injections suck so much.

J

Treetop

Caverjet = Alprostadal = PGE-1. Different names/forms, but same medication.

The issue in my post is that according to my measurements, it is not the PGE-1 that is causing my ache, even tho all the literature says it is the PGE-1. Maybe I'm recording my data in error, but then, research is what I do 24/7. -- So, I'm in a major state of confusion on this. Anyway, I guess I have to bite the bullet, and do some careful and costly experimentation. I guess I need to try PGE-1 by itself and see if the ache goes away. -- Unlike you, I seem to get less pain when the solution is new and more after it has been around a couple months. This is contradictory to all the documentation, but doesn't surprise me that much. I've seen guys have amazingly different responses to the herb Yohimbe, some loving it, and some getting violently ill from it. We is all different!!

FYI - According to research I've seen, PGE-1 deteriorates at about 6% per month when stored in the frig. and much faster at room temp. Don't know the exact amount at room temp, but it is at least 4-6 times higher. Which basically says - keep it in thr frig. Papaverine and Phentolamine showed no noticable deterioration after a month at room temp.

Big

Hey Tree

If you are going to experiment with combinations, only change 1 element (variable) at a time. I violated my own rule and screwed myself up by increasing both PGE-1 and Phentolamine at the same time (trying to save a few $), and now I'm not 100% certain of my data. You may want to try 30,2,30 for next go. The same 15 unit dosage will then give you a 50% increase in ONLY PGE-1, with dosage of the other elements staying the same. Post your results when you know them.

FYI also PGE-1 mostly controls rigidness, Papa and especially Phento, duration.

Big

Bigeyes,

Have you tried plain Bi-Mix yet??

That would settle your question once and for all.

You can get it from a member here if you wish -- and he will even send you a free sample to make sure its going to work before you have to buy a 5 or 10ml vial.

J

JimStars

I have not tried plain Bi-mix yet.

I've been getting conflicting info. Using 20, 30, 2 (PGE, Papa, Phento) -- A new solution works well with little pain. As the solution gets older (I have a six month old vial with a little left) the ache seems to increase. Since it is the PGE that deteriorates, it seems to me that it is the papa/pheno level causing the ache, but hard to be sure.

Second problem is cost of buying and trying differing mixes. I hurts to spend $100 or so bucks just to evaluate a mix, especially when it doesn't work worth a damn, and I haven't found anyone that will give or sell me a small amount for testing.

You mention getting it as a sample from a member here. Please expand on details.

Big

Hello wanted to chime in PGE equals hardness and hardness equals pain. The other two chemicals in tri mix are seldom associated with pain and for that reason are used in bi mix. I use a tri mix too it is light on the PGE and I only get some pain after my 1st ejaculation when I continue after 1st ejaculation I get discomfort that escalates to the second ejaculation about an hour later at that point.
I stop at this point having fun and/ or if i go on it is just to see the women flip out but it is sore as heck and the timing gets me nervous as to get to this point a 3rd ejaculation its a 5 to 6 hour jaunt and gets dangerously near priaprism many nights well going for a third round I succeeded in flipping out the woman and then needed to do aerobics in a cold shower or run up and down fire escape stairs for my efforts. Ha the crazy stuff we do for sex.
You need to dial it all in if you find you need more PGE-1 accept the pain or go to the end game solution implant.
best of luck I am considering implant now but have not exhausted injection solutions at all but I love the sound of full control bionics of course the bad reports make me hesitant too.

I wanted to also say often with repeated use and going at it strong for weeks, I have found I need less and less of the injections.
I can if I go way past recommended dosing of every other day and push it to a minimum of a shot a day and often two a day . Then be on without chemicals at all. The use it or lose system kicks in for me and I will fall into just unassisted sex no injections at all. This might be healing I find that I need less and less when in a torrid relation that last for a week plus. Getting into a relation I do need to take full dose have you noticed you need less? Maybe this is what is happening to you??

Hey tijv

Thanks for the input. I'm using 20, 30, 2 (PGE, Papa, Phento) and injecting 0.20 ml (20 units)
What is your mix?
How old are you?

I agree PGE controls hard, and according to all the documentation, also pain. I'm gonna see if I can get a trial order of Bi-mix, just to home in on the problem.

If the injections work well for you, why are you considering an implant?

Big