Difficulty reaching orgasm - solution worked for me

[Floridaspeedo]

Some guys complain an implant causes guys to have difficulty reaching an orgasm. If I look back at my history, I was having issues before the implant.

My Dr tried about 3 diff meds and Oxytocin. Nothing helped. Was more depressing than not getting hard before the implant.

I was reading about Peptides. I tried PT141.

I have magically for the past 10 days, had an orgasm every day. Oral, anal or by my masturbation.

It's not cheap but is has unlocked my "issue."

[edjohn]

It will eventually fry you unless you're an extremely casual user. Fair warning.

[Kodixx]

Floridaspeedo, I've had very good experiences with PT-141 and have posted about it in a few threads. Before the surgery I used it on average once a week and had used it for a couple years. I've gotten it from Mint Rx. I also found that THC/CBC(1:1) drinks work well, as do Sativa gummies. I'm about to try PT-141 again.

How many times a week do you use it ? How long have you been using it ? And what's your source of choice ?

- Chuck

I was reading about Peptides. I tried PT141. I have magically for the past 10 days, had an orgasm every day. Oral, anal or by my masturbation. It's not cheap but is has unlocked my "issue."

[LastHope]

Some guys complain an implant causes guys to have difficulty reaching an orgasm. If I look back at my history, I was having issues before the implant.

My Dr tried about 3 diff meds and Oxytocin. Nothing helped. Was more depressing than not getting hard before the implant.

I was reading about Peptides. I tried PT141.

I have magically for the past 10 days, had an orgasm every day. Oral, anal or by my masturbation.

It's not cheap but is has unlocked my "issue."

Floridaspeedo, how about PIV?

[fucked0ne]

“PT-141 acts as a melanocortin receptor agonist, primarily targeting the MC4 receptor in the central nervous system (brain). This action is thought to increase dopamine levels in the hypothalamus, a brain region involved in regulating sexual desire and arousal. Unlike medications like Viagra, which target the circulatory system, PT-141 works on the nervous system to enhance libido and sexual response.”

Couldn’t you just take something that upregulates dopamine? Or what about increasing free and bioavailable T?

[LastHope]

“PT-141 acts as a melanocortin receptor agonist, primarily targeting the MC4 receptor in the central nervous system (brain). This action is thought to increase dopamine levels in the hypothalamus, a brain region involved in regulating sexual desire and arousal. Unlike medications like Viagra, which target the circulatory system, PT-141 works on the nervous system to enhance libido and sexual response.”

Couldn’t you just take something that upregulates dopamine? Or what about increasing free and bioavailable T?

Good point F1. I'm currently experimenting with Caborgoline and Clomid to up my dopamine (+effectively keep prolactin to a low normal) and up my endogenous T to a high normal. Caborgoline has a non-zero risk of heart valve fibrosis when taken in high (Parkinson's) doses for sustained periods of time. I want to maintain my fertility at the moment, so not using exogenous T.

[fucked0ne]

“PT-141 acts as a melanocortin receptor agonist, primarily targeting the MC4 receptor in the central nervous system (brain). This action is thought to increase dopamine levels in the hypothalamus, a brain region involved in regulating sexual desire and arousal. Unlike medications like Viagra, which target the circulatory system, PT-141 works on the nervous system to enhance libido and sexual response.”

Couldn’t you just take something that upregulates dopamine? Or what about increasing free and bioavailable T?

Good point F1. I'm currently experimenting with Caborgoline and Clomid to up my dopamine (+effectively keep prolactin to a low normal) and up my endogenous T to a high normal. Caborgoline has a non-zero risk of heart valve fibrosis when taken in high (Parkinson's) doses for sustained periods of time. I want to maintain my fertility at the moment, so not using exogenous T.

I’m probably going to hop on hCG; I’ve tried exogenous test and it felt like castration. I would love to try Clomid but have a susceptibility to ototoxicity. I have never heard of Caborgoline and have no clue what it does.

[CanGetItUpButNotOff]

I had mixed results with PT-141 (a/k/a Bremelanotide a/k/a Vyleesi) and suspended use once I started TriMix which guaranteed an erection and also seems to help with orgasm.

[LastHope]

“PT-141 acts as a melanocortin receptor agonist, primarily targeting the MC4 receptor in the central nervous system (brain). This action is thought to increase dopamine levels in the hypothalamus, a brain region involved in regulating sexual desire and arousal. Unlike medications like Viagra, which target the circulatory system, PT-141 works on the nervous system to enhance libido and sexual response.”

Couldn’t you just take something that upregulates dopamine? Or what about increasing free and bioavailable T?

Good point F1. I'm currently experimenting with Caborgoline and Clomid to up my dopamine (+effectively keep prolactin to a low normal) and up my endogenous T to a high normal. Caborgoline has a non-zero risk of heart valve fibrosis when taken in high (Parkinson's) doses for sustained periods of time. I want to maintain my fertility at the moment, so not using exogenous T.

I’m probably going to hop on hCG; I’ve tried exogenous test and it felt like castration. I would love to try Clomid but have a susceptibility to ototoxicity. I have never heard of Caborgoline and have no clue what it does.

Caborgoline reduces prolactin (targeting low normal levels), is used off-label for DE, though the evidence base is not robust. They say it's a long-acting dopamine receptor agonist. It's not without some crappy GI side effects. No free lunch I guess!

From wiki:
Off-label
Cabergoline has at times been used as an adjunct to SSRI antidepressants as there is some evidence that it counteracts certain side effects of those drugs, such as reduced libido and anorgasmia. It also has been suggested that it has a possible recreational use in reducing or eliminating the male refractory period, thereby allowing men to experience multiple ejaculatory orgasms in rapid succession, and at least two scientific studies support those speculations.

[fucked0ne]

Good point F1. I'm currently experimenting with Caborgoline and Clomid to up my dopamine (+effectively keep prolactin to a low normal) and up my endogenous T to a high normal. Caborgoline has a non-zero risk of heart valve fibrosis when taken in high (Parkinson's) doses for sustained periods of time. I want to maintain my fertility at the moment, so not using exogenous T.

I’m probably going to hop on hCG; I’ve tried exogenous test and it felt like castration. I would love to try Clomid but have a susceptibility to ototoxicity. I have never heard of Caborgoline and have no clue what it does.

Caborgoline reduces prolactin (targeting low normal levels), is used off-label for DE, though the evidence base is not robust. They say it's a long-acting dopamine receptor agonist. It's not without some crappy GI side effects. No free lunch I guess!

From wiki:
Off-label
Cabergoline has at times been used as an adjunct to SSRI antidepressants as there is some evidence that it counteracts certain side effects of those drugs, such as reduced libido and anorgasmia. It also has been suggested that it has a possible recreational use in reducing or eliminating the male refractory period, thereby allowing men to experience multiple ejaculatory orgasms in rapid succession, and at least two scientific studies support those speculations.

You’re experimenting with this right now?