Hi all, I am new to this forum. My signature (if i filled it out properly) will show my history. I am currently trialing Bimix, and have some concerns. I am hoping that some of you can provide some feedback to assist me. thanks.
Specifically, I am concerned about how long it should take for the erection to decrease down to flaccid, or at least decrease down to the point where you do not have to consider going to the hospital.
I went to a (local) hospital with a priapism 4 hours after the first ‘test’ dosage (“.3”) that was administered (an hour away) at the Medical Center where i had my Prostatectomy DaVinci Surgery. It was not a fun experience, in the hospital. I was in the hospital for close to 4 hours. They first tried counter-injections to bring it down. They then did needle extraction to drain the blood. I was under a local, so I did not feel any pain, but there was discomfort, and it truly was traumatic.
I must really enjoy sex with my wife, because I have tried Bimix 3 or 4 more times (after I told myself that I would not use it again, after the priapism). I have tried the Bimix a total of 4 or 5 times.
First time, dosage was “.3” administered at the Medical Center (an hour away) where i had my Prostatectomy DaVinci Surgery (the ".3" is the standard amount that the Prostate Cancer administers to post Prostate Cancer Surgery patients who qualify for “injections”. Apparently it was way too much. By the time 4 hours came and went, I had not come down a bit. The nurse who administered it, examined me after an hour and was convinced that I was starting to come down (but that was not the case). I even took some of the Sudafed to assist (at the 2 hour mark, and again after 4.5 hours). I live over an hour away from the Medical Center, so I went to a local hospital. It has a great reputation, but it took them over an hour, close to 90 minutes, to start treating me after I had arrived there. To repeat, it was a nightmare situation, that i hope to never repeat.
After a phone call, two days later, the Medical Center concluded that the ".3" was too much for me. We scheduled a 2nd appointment for 2 weeks later, for a much smaller dosage.
Second time, dosage was “.1” administered again at the Medical Center (two weeks after the first attempt). This time, there was very little effect. The nurse asked me, and my answer was that I felt that I had achieved about 70% -75% erection in the office. Within an hour, things were totally down, and back to normal. The recommendation from the folks at the Medical Center was for me to increase to “.15 to .20” at home.
The third time, dosage was approx “.17”, at home. It was a great success. Good intercourse. However, as 4 hours approached, and things were not decreasing, I called the Medical Center . They were ready for me at the the Medical Center. I showered, got dressed, and figured “here I go again, another priapism, with the draining and everything”. However, short after 4 hours, things started to slowly go down. I actually started driving in the car (realizing it would take over an hour to get there). After about 20 minutes in the car, I realized that things were continuing to go down, so I made a U-turn, and headed back home. I was not totally flaccid until about 5-6 hours, but it did continue to decrease, until it became flaccid. I was greatly relieved.
The fourth time, dosage was about “.15”, at home. I achieved about a 90%-100% erection. Not as good as the .17, but usable. Once again, the erection continued longer that I had hoped. This time I did not call the Medical Center, but I continued to watch things. I actually did take a shower, and was ready to drive down to the Medical Center, just in case. It was around the 4 hour mark, that it slowly starting decreasing.
That was the last time. (about 2 weeks ago). We have only used Viagra since, as I debate my path forward.
So my primary questions relate to “the normal” or “the average” or maybe even the long end of “acceptable” erection duration?
Does anyone have an erection for about 4 hours? What is the duration of your erection, and how soon (after the injection) do you start to see things going down? I realize that it varies from guy to guy, but any numbers will help me get a feel for what others experience. Thanks.
Related information: My PSA was 6.2. My pre-surgery Gleason from biopsy was 4+3=7. The Robotic surgery was successful, the surgeon says he got it all, and saved both nerve bundles. There was some minor complications, due to prior surgery for hernia, and the surgeon had to take a path around the mesh that was put in during the hernia surgery. The post surgery biopsy was 4+3=7.
I have tried all the pills, and have had the best success with Viagra. I also purchased, and have used an Osbon Pump. With Viagra, the pump, and rings, I have had 90%-100% erection, but there is the “bend” point where the ring constricts things, down near the base of my penis. Dr Patrick Walsh’s book even addresses the issue of the bend – at the point of the ring constrictor.
I am not doing this for my wife, but she had some minor complaints about the bend point, and that it made it difficult for her to achieve the sensation, for her to achieve orgasm. I get as much satisfaction in pleasing her, to the point of orgasm, as I do in achieving orgasm myself. Therefore, her satisfaction is very important to me.
I have read about the success of Injections. I was excited to try the Injections. I was very pleased, and continue to be very pleased with the results of Injection. Truly, a couple of times, there was 100-105% percent erection, and my wife and I had the best sex since before surgery.
I am left in a point of confusion. What do I do now? My biggest concern and fear is having to go to the Hospital and go through the full drain experience again.
I think that if I knew with 110% certainty that I would always come down, around 4 hours (or preferably less) then I could continue with Injections (and without any worries).
However, each time, when I give myself a shot, in the back of my head, I wonder …. Will it go down? Or will I go to the Hospital.
I really wish that it would only last about 90-120 minutes (2 hours max). but I also do want the full 100% erection. So, though the 2nd time, with only “.1” brought things down in a much faster time frame, it was not really a usable erection.
I guess I will stop here, and see what your initial thoughts and recommendations are.
Age: 55; PSA 6.2; Biopsy: 1 of 10, Gleason 7 (3+4), Prostatectomy (DaVinci), PostOp: margins clear; post-op U/PSA: 0.04 (at 18 month); Viagra, and Osbon manual pump. Currently trialing Bimix (.3 is too much - had priapism; .10 too little)Age: 55; PSA 6.2; Biopsy: 1 of 10, Gleason 7 (3+4), Prostatectomy (DaVinci), PostOp: margins clear; post-op U/PSA: 0.04 (at 18 month); Viagra, and Osbon manual pump. Currently trialing Bimix (.3 is too much - had priapism; .10 too little)
New member - Fifties Male - don't want this buried!
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Re: New member - Fifties Male - don't want this buried!
Hey Fifties,
Every guy responds differently to injections... the type and strength of the chemicals used, etc.
Me, I used trimix and stopped.
Why? I was getting more and more sensitive with each injection.
I kept reducing my dose and kept having 3+ hour painful erections...and I had an ER visit for it early on. Fortunately, no blood drainage was required.
Now, I don't inject and levitra alone works where it didn't before.
Try and find a Uro that specializes in your area in ED and injections. That may help.
Sorry I can't offer anything better, but sometimes it takes a long term commitment to get the dose/chemical combination right.
BA
Every guy responds differently to injections... the type and strength of the chemicals used, etc.
Me, I used trimix and stopped.
Why? I was getting more and more sensitive with each injection.
I kept reducing my dose and kept having 3+ hour painful erections...and I had an ER visit for it early on. Fortunately, no blood drainage was required.
Now, I don't inject and levitra alone works where it didn't before.
Try and find a Uro that specializes in your area in ED and injections. That may help.
Sorry I can't offer anything better, but sometimes it takes a long term commitment to get the dose/chemical combination right.
BA
Age 54.
Open RRP in May of 2009. Gleason at biopsy, 3+3. Gleason after surgery, 3+4 with extra-prostatic extension. Stage III cancer. No incontinence issues. ED issues. Trimix for 5 months. Now, levitra alone is working at 10 mG.
Open RRP in May of 2009. Gleason at biopsy, 3+3. Gleason after surgery, 3+4 with extra-prostatic extension. Stage III cancer. No incontinence issues. ED issues. Trimix for 5 months. Now, levitra alone is working at 10 mG.
Re: New member - Fifties Male - don't want this buried!
Welcome to The Club. I use Trimix. My Uro started me at 0.1ml and had me increase as needed by 0.05ml increments. The goal should be to start too low and increase gradually until you get max hardness with minimal pain. But different doctors use different mixes, which dictates the dose.
As for duration of the erection, mine is about 1.5 hours using 0.08ml. But yeah, everyone responds differently I've seen. Anything longer than about 2 hrs is too long. Research shows antything longer than 6 hrs does permanent damage. Perhaps Trimix would be a better option for you. You need a good uro.
Good luck.
As for duration of the erection, mine is about 1.5 hours using 0.08ml. But yeah, everyone responds differently I've seen. Anything longer than about 2 hrs is too long. Research shows antything longer than 6 hrs does permanent damage. Perhaps Trimix would be a better option for you. You need a good uro.
Good luck.
Age 54
RP July 2010. All nerves spared on right, 25% on left
Pathology: T3b, Gleas 9, Pos Margins, EPE
Currently on ADT
Using Trimix successfully: 0.08ml; 20MCG Alprostadil 1MG Phentolamine 30MG/ML Papaverine
RP July 2010. All nerves spared on right, 25% on left
Pathology: T3b, Gleas 9, Pos Margins, EPE
Currently on ADT
Using Trimix successfully: 0.08ml; 20MCG Alprostadil 1MG Phentolamine 30MG/ML Papaverine
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Re: New member - Fifties Male - don't want this buried!
I wanted to add my comments as well. I am almost four years post DaVinci PSa surgery. The result was complete erectile failure. In other words nothing worked to give me an erection until I used Caverject. i changed to bimix due to the discomfort with alprostadil. I have now for nearly four years had excellent erections with about .15 bimix. I use it four to six times a month. "tonights the night"...lol
I have developed some plaque buildup, but it has not gotten any worse in four years. I have a very slight bend, but I always have had that even before ED. My concern is that the plaque will continue to worsen. I do notice a harder shell when injecting.
Your comments about long (four hour +) erections remind me that when I first started injections my urologist told me not to worry if I was softer (not rock hard) after 2 or 3 hours. I tend to stay somewhat erect for several hours and can even 'revive' my erection up to 5 or 6 hours. I still assume that it isn't a problem. I still use a VED and that might be why my plaque has not become a real problem.
I am guessing that somewhere down the road an implant will be necessary. My only concern is that the plaque buildup could make it more difficult. Hope this adds to your knowledge.
I have developed some plaque buildup, but it has not gotten any worse in four years. I have a very slight bend, but I always have had that even before ED. My concern is that the plaque will continue to worsen. I do notice a harder shell when injecting.
Your comments about long (four hour +) erections remind me that when I first started injections my urologist told me not to worry if I was softer (not rock hard) after 2 or 3 hours. I tend to stay somewhat erect for several hours and can even 'revive' my erection up to 5 or 6 hours. I still assume that it isn't a problem. I still use a VED and that might be why my plaque has not become a real problem.
I am guessing that somewhere down the road an implant will be necessary. My only concern is that the plaque buildup could make it more difficult. Hope this adds to your knowledge.
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