My new ED regimen: confused and new plans

Anything goes when it comes to ED.
Flavio
Posts: 907
Joined: Wed May 19, 2010 4:56 am

My new ED regimen: confused and new plans

Postby Flavio » Sat Nov 28, 2020 11:41 am

Last night I tried the 'big three' combination (avanafil + oral phentolamine + apomorphine SL) and I'm afraid it was disappointing.

My erection was good but not nearly as good as it used to be. And, for the first time ever, manual stimulation was necessary for me to get erect. Usually, just looking at my girlfriend's naked body is more than enough to get a hard erection but not this time.

I didn't feel as aroused as I normally do, I felt somewhat 'sedated' and this could be related to apomorphine. I remember I tried cabergoline a few years ago and I had a similar negative experience.

Hypotension was the worst part. I felt no dizziness when I tried apomorphine on its own but it was too much when I combined the other two drugs. Again, this same thing happened with cabergoline :(

I can't stress this enough: combination therapy increases efficacy but it also increases the risk of side effects. Always consult your urologist before you decide to try any new treatment or supplement.

I know I got a bit carried away on my thread about apomorphine, I had high hopes for this new regimen but now I'm not so sure. And I'm starting to think that my previous brand Zyprima was probably not so effective and the benefits were derived exclusively from Cialis. I'd love to know if anyone has tried the apomorphine tablets from The ED Clinic and had better results. So far, I've had little luck with centrally acting drugs (apomorphine, cabergoline).

Maybe I'm overreacting?

I'm confused and I don't know what to do. I still believe in combination therapy and I'm convinced the trick is to find the right combination and the right doses. Here are my future plans (i.e. treatments I would like to try next):

a) Cialis daily 5 mg: it allows for great spontaneity, I hear nothing but great things about it and it could improve vasculogenic health.

b) Oral papaverine, maybe it could replace oral phentolamine: I know RUGIET sells this but it is not an approved ED treatment and I don't know any studies.

c) Bayer's Serenia or other natural anxiolytic could be helpful, as well.

Any thoughts?
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Flavio
Posts: 907
Joined: Wed May 19, 2010 4:56 am

Re: My new ED regimen: confused and new plans

Postby Flavio » Sat Nov 28, 2020 12:29 pm

An interesting study on combination therapy (incl. oral papaverine and apomorphine):

https://www.nature.com/articles/3900816
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Flavio
Posts: 907
Joined: Wed May 19, 2010 4:56 am

Re: My new ED regimen: confused and new plans

Postby Flavio » Sun Nov 29, 2020 9:41 am

After my disappointing experience with apomorphine, I think I might return to a food supplement called SEREDYN.

I have used it in the past in combination with Cialis with excellent results and zero side effects (e.g. no sedation, no hypotension). The only reason why I stopped it is because I didn't want to take too many pills and I thought I didn't need it anymore.

Why SEREDYN may be helpful in cases of sexual performance anxiety:

a) It contains suntheanine, which improves dopamine (the 'love hormone' that triggers erections) and promotes relaxation.

b) One of the ingredients is vitamin B3 (niacinamide) which I only recently found out that may improve erectile function;

https://www.singlecare.com/blog/can-vit ... sfunction/

https://www.researchgate.net/publicatio ... slipidemia

c) Magnesium taurinate for its anti oxidative properties.

More on SEREDYN:

https://bioneurix.com/products/seredyn
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Flavio
Posts: 907
Joined: Wed May 19, 2010 4:56 am

Re: My new ED regimen: confused and new plans

Postby Flavio » Sun Nov 29, 2020 11:24 am

This excellent article from Nature's Best mentions suntheanine, one of the ingredients of SEREDYN, as a natural treatment for ED:

https://www.naturesbest.co.uk/pharmacy/ ... src=ntb519
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.


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