do alpha-1 blockers help ED?

Anything goes when it comes to ED.
Implant_Curious
Posts: 46
Joined: Fri Jul 16, 2021 6:14 am

do alpha-1 blockers help ED?

Postby Implant_Curious » Sun Jul 25, 2021 4:38 am

wondering about silodosin or tamsolusin effects also on PE in people without BPH
35 gay male, top/vers. ED complicated by long-term SSRI and quetiapine use as well as smoking previously. Currently on 5mg cialis daily. Also tried sildenafil 25-100mg on demand, all successful.

mr.skin
Posts: 319
Joined: Tue Jan 09, 2018 9:51 am

Re: do alpha-1 blockers help ED?

Postby mr.skin » Mon Jul 26, 2021 6:11 am

Yes.

Less sympathetic tone helps with erection and pe
1993
ED since 2012
nothing works properly

Implant_Curious
Posts: 46
Joined: Fri Jul 16, 2021 6:14 am

Re: do alpha-1 blockers help ED?

Postby Implant_Curious » Mon Jul 26, 2021 9:03 am

any alpha blockers you recommend?
35 gay male, top/vers. ED complicated by long-term SSRI and quetiapine use as well as smoking previously. Currently on 5mg cialis daily. Also tried sildenafil 25-100mg on demand, all successful.

Flavio
Posts: 906
Joined: Wed May 19, 2010 4:56 am

Re: do alpha-1 blockers help ED?

Postby Flavio » Mon Jul 26, 2021 5:59 pm

Yes, alpha blockers are very helpful and there are many studies that show it.

The problem is finding the right drug.

I have tried several alpha blockers and the only thing that worked for me was oral phentolamine (formerly known as Vasomax).

I take phentolamine 1 hour before sex, in combination with udenafil.

Side effects may include headaches, nasal congestion, tachycardia and hypotension.

Oral phentolamine is not approved in the US but it seems to be a popular treatment in China, where you can find several brands.
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Implant_Curious
Posts: 46
Joined: Fri Jul 16, 2021 6:14 am

Re: do alpha-1 blockers help ED?

Postby Implant_Curious » Tue Jul 27, 2021 1:06 am

would something like silodosin also be an option?
35 gay male, top/vers. ED complicated by long-term SSRI and quetiapine use as well as smoking previously. Currently on 5mg cialis daily. Also tried sildenafil 25-100mg on demand, all successful.

Flavio
Posts: 906
Joined: Wed May 19, 2010 4:56 am

Re: do alpha-1 blockers help ED?

Postby Flavio » Tue Jul 27, 2021 12:33 pm

Implant_Curious wrote:would something like silodosin also be an option?


Never hear of that one, only your doctor can say what's best for you.

I remember I tried alfuzosin and terazosin with zero results but they seem to work for other men.
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

mr.skin
Posts: 319
Joined: Tue Jan 09, 2018 9:51 am

Re: do alpha-1 blockers help ED?

Postby mr.skin » Tue Jul 27, 2021 2:17 pm

Doxazosin works for me though I get a very stuffy nose.
1993
ED since 2012
nothing works properly

Phil65
Posts: 146
Joined: Sun Oct 28, 2018 2:25 pm

Re: do alpha-1 blockers help ED?

Postby Phil65 » Thu Sep 23, 2021 2:27 am

Could one currently on a different BP medication take a single dose of Doxazosin (4mg?) an hour or two before sexual activity or should I ask my GP to switch my BP med to Doxa?
TRIPLE P SUPERMIX (30-2-50)
Papaverine 30mg/ml - Phentalomine 2mg/ml - PGE1 50mcg/ml
(+ 0.15mg/ml Atropine)

Phil65
Posts: 146
Joined: Sun Oct 28, 2018 2:25 pm

Re: do alpha-1 blockers help ED?

Postby Phil65 » Tue Oct 05, 2021 2:00 am

Okay, let's try it this way...

Can anyone tell me how they incorporate a 4mg dose of Doxazosin? Does one take it when going to bed, the night before sex (so roughly 24 hours before) or 1 hour or 2 hours before sex like Viagra?
TRIPLE P SUPERMIX (30-2-50)
Papaverine 30mg/ml - Phentalomine 2mg/ml - PGE1 50mcg/ml
(+ 0.15mg/ml Atropine)

Namirrah
Posts: 89
Joined: Tue Mar 13, 2018 1:45 pm

Re: do alpha-1 blockers help ED?

Postby Namirrah » Tue Oct 05, 2021 4:57 am

I take 2 mg Doxazosin before bed.

It does make a difference concerning nocturnal erections. They haven't completely returned, but they occur more often and I usually have at least a partial erection in the morning. It does improve my flaccid hang. And, it seems to make my ED meds more effective. Oral meds have never been effective for me. But, Doxazosin reduces the amount of Trimix needed and increases the time that it works.
Age: 39, Diabetic (well controlled) HBP (since teens, less well controlled, but ok),
mild ED for 3 years, l arginine l citrulline and norvaline (amino acid stack) helped.
Pills: ineffective. Started trimix: 6/24/18, EXTREMELY effective.


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