frequent injectors question

Sticking a needle Where? Courage, guidance and help.
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Wiggles123
Posts: 137
Joined: Sat Apr 23, 2022 10:12 am

Re: frequent injectors question

Postby Wiggles123 » Tue May 03, 2022 7:56 am

We always go 3+ hours, even when I wasn't implanted (just employed toys, etc...). Wife jokingly calls 2 hours a quickie. :lol:
AMS700 CX 21cm with 3 RTE 4-2019 by Dr Natale - failed 5-2021. Revision 6-2021 with issue (scrotal hematoma and infection). Dr. Ryan Terlecki revision 3-28-2022 (AMS700 CX 21cm with 1.5cm RTE). Cylinder failure at 18 months. 24cm AMS700 CX 11-29-2023.
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ape1100
Posts: 233
Joined: Wed Feb 23, 2022 12:35 pm

Re: frequent injectors question

Postby ape1100 » Tue May 03, 2022 8:42 am

Wiggles123 wrote:We always go 3+ hours, even when I wasn't implanted (just employed toys, etc...). Wife jokingly calls 2 hours a quickie. :lol:


hell yeah, got to get it in now while we can! :lol:
50+ yrs old. married 25+ years. hypothyroid, on TRT. 10+ years ED, viagra, cialis now 50% ineffective. now on trimix 2MG phentolamine/30MG papaverine/20MCG alprostadil
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Wiggles123
Posts: 137
Joined: Sat Apr 23, 2022 10:12 am

Re: frequent injectors question

Postby Wiggles123 » Tue May 03, 2022 5:33 pm

Agreed!
AMS700 CX 21cm with 3 RTE 4-2019 by Dr Natale - failed 5-2021. Revision 6-2021 with issue (scrotal hematoma and infection). Dr. Ryan Terlecki revision 3-28-2022 (AMS700 CX 21cm with 1.5cm RTE). Cylinder failure at 18 months. 24cm AMS700 CX 11-29-2023.
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nitejazz
Posts: 16
Joined: Tue Feb 22, 2022 7:15 pm

Re: frequent injectors question

Postby nitejazz » Sat May 07, 2022 9:51 pm

A little research into pharmacology of the drugs contained in Trimix shows the halflife of papavarine to be 30 to 90 minutes, phentolamine is 180 minutes and alprostadil given intracavernously is undetectable in the blood stream in less than 60 minutes. Typically 3 to 4 halflives of a drug are considered to make it effectively not present in the body especially for drugs with no metabolites that are active. Based on this information I would not worry about changing the dose after less than 24 hours. I' not a physician but have 40+ years administering vasoactive drugs for anesthesia purposes. YMMV, but personally I have no worries about repeating a dose 2 or 3 days in a row.
74, married 44 years, ED for about 18 months tried pills not much effect with bad headaches, tried VED not happy, finally found trimix with the suggestion of cardiologist 8-) still experimenting with dose but happier.
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Hunchback
Posts: 543
Joined: Sun Apr 30, 2017 5:00 am

Re: frequent injectors question

Postby Hunchback » Tue May 10, 2022 5:25 am

Having your injection work "too long" screams "first world problems" for me lol
40 years old, married. ED all my life because of spinal cord injury caused by a tumor in early infant age. Using standard EDEX20 since 2007. Increasingly bad results with EDEX in the last few years, but had very good results for at least 10 years.
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