PDE5 pills & back pain - any solutions?

Anything goes when it comes to ED.
Biker22
Posts: 57
Joined: Sat May 28, 2022 12:17 pm

PDE5 pills & back pain - any solutions?

Postby Biker22 » Mon May 08, 2023 1:06 pm

Hi

I have real issue taking PDE5's and lower back pain. I have had 10 years of on/off Lower Back pain.

If I take any of the PDE5 pills then I end up with lower back pain - even 25mg Sildenafil will give me a low grade - cant quite ignore back pain.

I've been told doctors believe that as PDE5 are systemic acting that they also open blood vessels in your back and these might press on the nerves near/around your back?

I'm just wondering if anyone has found a work around - managed the pain somehow?

The only paper I found was this one from 2016 - they were using
Aceclofenac (diclofenac) 100 mg + Chlorzoxazone 250 mg (muscle relaxant) + Paracetamol 325 mg.

It did seem to work but thats a lot of meds to get over the side effects of PDE's and each of above, each will have their own side effects


https://www.researchgate.net/publicatio ... N_PATIENTS
Last edited by Biker22 on Tue Aug 06, 2024 3:28 am, edited 1 time in total.
50yrs Old, had ED all my life.
Titan 24cm + 1cm RTE.

tonyareias
Posts: 100
Joined: Tue Jan 04, 2022 10:26 pm

Re: PDE5 pills & back pain - any solutions?

Postby tonyareias » Mon May 08, 2023 6:06 pm

Possible back pain is a side effect of Cialis. Try Viagra or Levitra.

Biker22
Posts: 57
Joined: Sat May 28, 2022 12:17 pm

Re: PDE5 pills & back pain - any solutions?

Postby Biker22 » Tue May 09, 2023 4:05 am

Yep Cialis is a well known for causing lower back pain. That’s why so many guys can’t use it.
I’ve used every PDE5 on the market. Sildenafil works better but I can’t get the dose high enough for pills only effect without all the usual headaches, blue vision and back ache

Even 25mg Sildenafil daily gives me back ache. So I occasionally use 25mg Sildenafil when I use injections (invicorp).

I just wondered if anyone had same issues any protocol/ tips they found that worked?
50yrs Old, had ED all my life.
Titan 24cm + 1cm RTE.

frank66665
Posts: 1463
Joined: Wed Mar 25, 2020 11:18 am

Re: PDE5 pills & back pain - any solutions?

Postby frank66665 » Tue May 09, 2023 4:34 am

hwictried vardenafil? it is more selective than sildenafil and works better with fewer side effects
56, ED since 2010, pills work but not always and well, trt in progress improved but not so much, myocardial infarction january 2016, new stent september 2016, hypertension, venous on 1/23/23 titan one touch 22, no rte dottor Gabriele Antonini Italia

ftwabeck3533
Posts: 170
Joined: Sat Jun 22, 2019 3:21 pm
Location: South Alabama
Contact:

Re: PDE5 pills & back pain - any solutions?

Postby ftwabeck3533 » Tue May 09, 2023 8:11 am

Biker22 wrote:Yep Cialis is a well known for causing lower back pain. That’s why so many guys can’t use it.
I’ve used every PDE5 on the market. Sildenafil works better but I can’t get the dose high enough for pills only effect without all the usual headaches, blue vision and back ache

Even 25mg Sildenafil daily gives me back ache. So I occasionally use 25mg Sildenafil when I use injections (invicorp).

I just wondered if anyone had same issues any protocol/ tips they found that worked?


Very interesting. I've been battling a lower back pain, feels like a sciatica issue, for months -- it does not go away. I've never heard of the connection of sildenafil (PDE5) and back pain. I take 20mg a day for penile tissue maintenance.

Has anyone laid off the pill(s) for a few days and experienced a drop-off in back pain?
Born 1955, Erectile Dysfunction, Robotic Prostatectomy (Oct 2018, Dr Bugg @ UCA, Birmingham, AL), PSA<0.007, Trimix User (30 mg Papaverine HCL, 1 mg Phentolamine MES, 10 mcg Alprostadil per 1 ML. My dose is 0.16 ML)

cosmo89
Posts: 9
Joined: Thu Oct 18, 2012 9:05 am

Re: PDE5 pills & back pain - any solutions?

Postby cosmo89 » Tue May 09, 2023 8:26 am

I have spinal stenosis and back pain. But not crippling. I KNOW that statins, in particular lipitor, will give you back pain. I'm switched to pravastatin and it is doesn't affect me as bad. The PDE5's don't bother my back much. Only take them once a week usually.

tonyareias
Posts: 100
Joined: Tue Jan 04, 2022 10:26 pm

Re: PDE5 pills & back pain - any solutions?

Postby tonyareias » Tue May 09, 2023 6:34 pm

Try Spedra / Stendra (Avanafil), is the most weak and selective of PDE5i.

Biker22
Posts: 57
Joined: Sat May 28, 2022 12:17 pm

Re: PDE5 pills & back pain - any solutions?

Postby Biker22 » Wed May 10, 2023 8:13 am

Thanks for all the replies.

Sildenafil I can sorta tolerate at 25mg with minimal back pain - but it is there. The listed side effects for Sildenafil are muscle ache/ spasm.

So daily tadafil is really bad back ache for me. Def can’t use this one

The only other PDE5’s are Avenafil and varndenafil - is this correct?

I have both in medicine cabinet so I will try and see if I can tolerate without any back pain. They both didnt perform well enough for sex but even if they allowed me to masterbate that would be progress.

I’m really getting fed up about this. There always seems to be a non surgery solution within my grasp but I can’t use because the solutions gives me side effects I can’t tolerate.

PDE5 - back ache
VED - hemarrhoids. Every time. Checked with Prof Ralph if this was VED or Pde5’s - he said VED. That’s backed up with my ED diary too.

It would be progress if I could have a toss without sticking a needle in it each time!

I’m off for Botox (Bocox) middle of next month. I’ll let you know how I get on. Research papers says it helps in conjunction with PDE5 etc A user on here has found the same - so adjunct but not a solution on its own.
50yrs Old, had ED all my life.
Titan 24cm + 1cm RTE.

Flavio
Posts: 906
Joined: Wed May 19, 2010 4:56 am

Re: PDE5 pills & back pain - any solutions?

Postby Flavio » Sun May 14, 2023 1:46 pm

Same here.

I've experienced back pain for a few weeks, PDE-5 inhibitors or covid may be possible causes.
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Flavio
Posts: 906
Joined: Wed May 19, 2010 4:56 am

Re: PDE5 pills & back pain - any solutions?

Postby Flavio » Sun May 14, 2023 3:46 pm

UPDATE: I started taking an antiviral yesterday and my back pain 'magically' disappeared, as well as the respiratory symptoms. This is definitely covid related!
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.


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