First PGE1 injection at office - 2nd dosage advice

[coldbrew]

Hello,

Friday am I had my first shot at the uro.
I was prescribed PGE1 20mcg/ml. He started at .40 which is actually (8 mcg). Right?

I had a reaction, but no lift off. Meaning it got fuller, not close to intercourse erection. It lasted for 10-15 mins (guessing). It was gone before I left the room.
He said in 24 hrs I could move up .10 to .50 (10 mcg)
I asked him since I was not close to full erection should I go up .20 to .60 (12 mcg)
He said that would probably be fine. He said it would have better effect at home instead of office room. I know he probably wants the erection to last no more than 30 mins which is fine with me, but I have to get there first.

What is your opinion on moving to .60 injection? Given my response at .40, will an extra .10 do much at this strength to do 2nd dose at .50?
Searching this site I am not finding a lot of experiences using PGE1 alone. Most people are using a trimix.

[bldoink]

I'd bump it the 10 like suggested. See what happens at home and with stimulation. I'm a strong believer in adding in a cock or constriction ring. I find it helps me quite a bit. However, not near as tight of one as with using a VED alone. For using with my injection (PGE1 but stronger mix) I use a novelty ring (Lyps brand set) behind the boys which allows me to use less PGE1 and makes it last longer. At this point I'm very happy with my Mono-mix AKA PGE1 or Alprostadil. I'm using 15 units of a 80mcg/ml which is pretty potent. I wouldn't suggest you using more than needed so hopefully it will remain effective longer but I'm not sure if my logic is valid. And yes I believe your math is correct.

[rahod1]

Hello,

Friday am I had my first shot at the uro.
I was prescribed PGE1 20mcg/ml. He started at .40 which is actually (8 mcg). Right?

I had a reaction, but no lift off. Meaning it got fuller, not close to intercourse erection. It lasted for 10-15 mins (guessing). It was gone before I left the room.
He said in 24 hrs I could move up .10 to .50 (10 mcg)
I asked him since I was not close to full erection should I go up .20 to .60 (12 mcg)
He said that would probably be fine. He said it would have better effect at home instead of office room. I know he probably wants the erection to last no more than 30 mins which is fine with me, but I have to get there first.

What is your opinion on moving to .60 injection? Given my response at .40, will an extra .10 do much at this strength to do 2nd dose at .50?
Searching this site I am not finding a lot of experiences using PGE1 alone. Most people are using a trimix.

Sounds like weak formula. Should be 100 mcg/ml...so injecting 20 units = 20mcg. You shouldn't need to inject a larger VOLUME of 40 units which only gets you 8mcg! I that doesn't work..go to trimix.

[bldoink]

The brand name PGE1, "Edex" comes in 10, 20 or 40mcg/ml with the user injecting the whole ml, so what he is starting at is a reasonable starting point. If he bumps up to .5 of his mix he will be at the lower Edex (Edex 10) potency. I started on the Edex 10, about where he will be at, but had to move up to the Edex 20 before it worked. He has a good ways to go before he needs to give up on mono-mix. The pharmacist commented to me that my 80mcg/ml was a pretty heavy mix.

[Hunchback]

Go slow, you'll see how it goes. One-two tries means nothing, this treatment is not "exact science"

[antelope]

My experience is with Trimix only, but notching the dosage up (or down) is certainly an accepted protocol. I wouldn't hesitate to notch up more aggressively at first until you find the "Cinderalla" zone. Generally speaking, the worst that can happen is that you have a glorious, throbbing, extended erection that may require a warm soak and/or a dose of Sudafed or generic equivalent. You might also find that visual stimulation such as you might find on adult web sites to be beneficial. All the best. Here's to hard times.

[antelope]

Goldilocks, not Cinderella. My bad.

[coldbrew]

Yes, I know going slow is best, but I would like to prick myself less as possible to find dose to allow good times.
This seems to be a low strength compared to other mixes. I'm sure moving up .20 from first dose with PGE1 20mcg is not like moving up .20 on a trimix.
Being new to all this I do not want to have 3 hr erection, and get scared. We are going on a trip this coming weekend, and I would like to have success.

We did not have any alone time yesterday to try the .50 injection. Hopefully tonight will be better. If not I will do it later tonight by myself. I think .60 would have been better, but .50 is loaded in fridge.
Plan is to inject tonight, then Tuesday night. Hopefully, after Tuesday I will know what is needed for a great Friday night.

bldoink, how many does did you do from 10 to 20? Is that number delivered 20mcg?

antelope, that is what I was thinking. This is weak strength, and if I did use just a little too much I do not think it would send me to hospital. I almost would like to use dose that worked great then back down. This would just assure me that it will work for me. However, I am the cautious type.

Hunchback, I know sound advice. I have 2 possible injection times before we start vacation on Friday.

Thanks for all the advice. This forum has a lot of knowledge. I think I read that the average person ends up at around 20mcg of PGE1.

[bldoink]

I liked my regular Uro a lot as a person and as a doctor for issues other than sexual health. He was great at diagnosing my cancer and dealing with stones. However, he wasn't there for me on the erection issues. After arriving at a completely non performing dick after RRP (went to a different Doc for that surgery as my Uro didn't have the DaVinci stuff.) he tried me on Viagra, ending up at the 100mg tabs. All they did was plump it up a tiny bit with stimulation. Useless. Then we went the VED route. I received no instructions other than the video that came with it. That worked I guess but does leave a lot to be desired and that's another story. He then gave me a script for Edex 10. No instruction, no in office injection, just a script to figure out on my own. I had to develop my own injection technique. I hadn't discovered this forum yet. Fortunately the insurance I had then covered Edex but only for a very few per month. Ration city! Besides the Edex 10 only gave me enough of an erection to make me dream of an erection. It gave hope but was useless (where you are?). The next step was a script for Edex 20. That gave me a 4+ hour boner that had me icing it down to avoid panic and an ER trip. 6+ hours later I'd still have a fair but diminishing boner. On top of that there was pain involved which does interfere with the pleasure but it was wonderful getting boned out again although I did lose some length from the surgery. Oh well!

After all that blather the answer to your question is I went directly from Edex 10 to Edex 20 because that's what they come in. Yes the 10, 20 or 40 reference on the Edex refers to the PGE1mcg/ml. The Edex is prepackaged in syringes for one time use per syringe. It mixes powder and liquid in the syringe. The syringe plunger only goes one way, down and can't be withdrawn. The compounded mix along with my 31g syringes is, IMHO the far better way to go. The only advantage of the Edex is that it has a fantastic shelf life.

More blather. I found myself not injecting the full ml of the Edex 20. I eventually found the sweet spot between pain and rock hard boner. Also, the pain thing seemed to ease off after awhile. Unfortunately my insurance quit covering Edex altogether which eventually led me to compounded PGE1. My pharmacy calls it Mono-mix. My GP who wrote it, wrote it as 40mg Alprostadil in .5ml saline or something like that. My Uro retired. Actually my GP just left too and I have an appointment at a new Uro soon.

I strongly suggest 2 things:

#1) Read up on injection techniques to avoid frustration. There are threads on this forum and elsewhere. Many do but I will not recommend an auto injector. If I had a place to anonymously post it I would do an injection video as I'm very happy with my technique but I'm not keen on the world watching me stick a needle in my dick.

#2) Try a novelty cock ring set. I like the Lyps 3 ring set but another member uses a similar set that I think is a different brand. They help me a lot and allows me to use less meds. I don't use all three rings. Mainly I use the large one at the base behind the boys but you get three to play with..... !!!BONUS!!! It turns out my wife likes the way the rings hold the package resulting in her spending more time playing. She likes the boys packaged separately too and the little ring works for that but that's for her when I do it. !!!BONUS!!!..... Obviously your mileage may vary.

Wow, that got kinda long. I hope it is helpful. I'm sure I'll have to come back and edit something.

[coldbrew]

yes, your post was most helpful. If jumping from 10 to 20 mcg did that to you I will go slow.
Like I said I will do 10 tonight. How much was left in syringe doing 20?
Maybe 12-15 may be my range, who knows. I do not want an experience like you going straight to 20 mcg
I have 2 injections planned before this weekend trip. I want to be ready, and not be disappointed.