Reklaw wrote:Simbarn wrote:Reklaw wrote:
I’d just like the thankyou for taking your time to write this incredible response, I’m absolutely mind blown by how accurate it is, you’ve basically articulated much of what I’ve long thought but couldn’t quite explain. I’ve screen shotted this text, please keep up the good work.
I'm very happy that it has helped you. Makes the effort worthwhile.
I tried to send you this in a PM but every time I tried to send it it’s goes in my outbox as opposed to my sent box for some reason. Here is my message…
Hello, I’d just like to thank you for contributing to my thread about circumcision induced ED. Your theory about the NO pathway is the only theory I’ve ever read since I’ve been circumcised and thus had ED (3 years) that makes any sense. I know for a fact that the lack of sensation I have from circumcision is the cause of my ED, there seems to be a two way response between the brain and the highly sensitive foreskin. I no longer even feel aroused, a couple of months back I had a naked 10/10 naked Polish girl infront of me and I didn’t even feel aroused. When your uncircumcised you feel your foreskin move which send a signal to the brain which creates a feeling of Euphoria which triggers and erection. Now I don’t have any sensitive skin so i don’t have the same response in the brain.
Do you think there is anyway I can improve my situation given that the NO pathway is likely involved? I’ve read a few studies which have said that L-Arginine and L-Citruline may help with NO related ED. I’ve also read that R-Lipotic acid may improve function of the Endothelial cells, and I’ve seen on a diagram that Endothelial cells are somehow related to the NO pathway.
I’m also considering flying to Eastern Europe for stem cells therapy in next winter.
Thanks for your time
When you send a private message it goes into your outbox first, I will see I have a message from you, once I open it, it will then appear in your sent items.
I am sorry but I do not have any solid suggestions with regard to repairing the damage that may have been done due to a circumcision causing serious loss of sensation. I would suggest trying to find something new that may cause nerve regeneration and growth to occur. I feel this is what happens in the infant, neural plasticity at that age in those tissues must be much stronger than when we are older, plus the penis is still growing and developing. Stem cell therapy may hold some promise here in the adult penis.
The other option is to bypass the NO pathway when trying to have an erection, the only way I know how to do this is with an IC injection of a drug which acts on the smooth muscle directly, Trimix has these ingredients, it also has phentolamine which supresses the inhibitive mechanism in the penis, which may also help you considerably as this simply makes anything that is trying to cause an erection to occur more effective.
A medication that also heightens arousal in the brain may also help, as this may strengthen the psychogenic erectile pathway, sending a stronger signal to the penis. Apomorphine is one such drug that has been used for this purpose.
I do not think there is an issue with the NO function in your penis, so trying to improve this may yield no improvement. Triggering it in the first place is more likely the problem IMO.
Do you still have nocturnal erections? Can you still reach orgasm and ejaculate and with how much difficulty since the procedure?
Age 57, ED issues for 15-20 years. Testosterone replacement with Enanthate and Ovidrel. Currently using generic Tadalafil 2.5mgs and Resveratrol daily.