New to Trimix - disappointing so far?

Sticking a needle Where? Courage, guidance and help.
BearsWin
Posts: 51
Joined: Thu May 12, 2022 11:37 pm

New to Trimix - disappointing so far?

Postby BearsWin » Thu Aug 18, 2022 10:15 pm

Hi, very glad to find this forum.

ED progressive for ~ 15 years, currently 56 years old. History of hypertension and concern for veinous incompetence. Got some serious varicose veins (legs).

Did well with oral meds from late thirties until the start of this year but progressively disappointing. Went to the urologist and started with Trimix a couple month ago with what I now understand was a pretty low concentration at ~ 8 mcg prostaglandin. Nothing happened for me on 5 units, increased up to 20, still not much, uro changed me to formulation with 20 mcg prostaglandin.

Managed to get something going with 20 units on this increased concentration but nothing like what I read on this forum with rock hard erections lasting ~ 2 hours. Maybe 80% erection which said adios after ejaculation and wasn't good enough for my wife's preferred positions.

I'm planning to try 30 units but I'm gettting discouraged. My experience seems far less optimal than other folks and I'm already at many multiples my original dosing. Uro says 99% respond to this but I'm not feeling it. Maybe it works far better for men with nerve issues stemming from RP as opposed to vascular problems?

Anyway, is there long term hope remaining? Starting to serious entertain the implant idea.

Thanks!
Born 1966. PDE-5s since age 40. Decreasing efficacy age 50. Started on Trimix 2022 - variable response even at high doses. Coloplast Titan 11/1/22 Dr. Yafi UCI, submuscular/ectopic reservoir. History of hypertension. Married, Nevada.

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bldoink
Posts: 3918
Joined: Mon Apr 03, 2017 12:58 am
Location: Fl.

Re: New to Trimix - disappointing so far?

Postby bldoink » Thu Aug 18, 2022 10:55 pm

Welcome to the forum.

I'm using about 15 units of alprostadil mono-mix at 80mcg per ml plus silicone novelty/sex shop cock rings.

The novelty cock ring is worn around the shaft behind the boys seems to help boost the injections for me a fair bit. I highly recommend giving the rings a try. Y want the rings to just slow the blood flow and not stop it like when using constriction rings with a VED as your ED solution. You'll need to experiment and expect rejects. There are a number of ring types you can try.

You have a fair amount of room to increase the strength of your dose left for you.

Good luck.
R.R.P 2011 Mayo Jacksonville, Dr. M. Wehle. Not nerve sparing. C in margins. Radiation 2023, V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ 8 - 14 units. Originally Edex20, then compounded PGE due to cost. Inject. 12 yrs. It works. Treasure coast of FL.


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