Venous leak: some information

[naginati]

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[Fanouris]

Everything that you write it's the same I have the Ed started at 22 I am 24 now but I look a lot order also because of the elastin as u say I just did a vein surgery in the leg cause my veins was very big....
What should I do now I don't know...

[Larry10625]

Everything that you write it's the same I have the Ed started at 22 I am 24 now but I look a lot order also because of the elastin as u say I just did a vein surgery in the leg cause my veins was very big....
What should I do now I don't know...

Talk to your family doctor and see if there is a high implant surgeon there. If there is, ask your doctor to refer you to him (or her) and go from there.

Larry

[Ricardo71]

Hi guys,

I'm 30 and venous leak has been eating me alive since age 22. Since the begin of this sh*t I have been researching a lot. At age of 25 I've managed to get a job in a pharmaceutical company and could read some dossiers about venous leak. Well, the problem of doctors is that they are unaware of it. This illnes exists.

Some important information:

1 when you think you suffer from venous leak the first thing to do is to go to doctor and see if you have a varicocele. The doctor can provide a diagnosis with Valsalva maneuver ad even better with scrotal ultrasound.

2 if you don't have varicocele (or even if you have it) look at the veins on your leg (especially those behind the knee or in the internal side of your feet). Probably you will notice varicous veins, or blue veins, or a lot of superficial violet capillars (this is not the rule, but there is a good probability you have them if you are suffering from venous leak)

3 you could also develop (maybe later in time) Hemorrhoids

4 look at the legs of your mother (or father) and those of your grandparents. If you have venous leak, surely one of them suffers from varicose veins.

Why do you have to check for this signs? Because venous leak is not just an illnes of the penis, venous leak is a general venogenic disorder of the body. There are really few doctors who can do this association. The vast majority of them says: "you are too young, it's all in your head". Bullsh*t.

Well, why do I say that it is a general venogenic disorder of the body: according to the dossiers I've read there is a general "genetic" problem in patient with venous leak. Normally patients with venous leak develop this problem when they are 20 years old (some patients are born with venous leak mostly because of defective valves, some develop it when they are 30). But why the vast majority develops it at 20-22? Because that's the point in time when your body stops producing elastin and you have to live your entire life with the reservoir of elastin you have produced until 20 years old (Elastin is a highly elastic protein in connective tissue and allows many tissues in the body to resume their shape after stretching or contracting). When you have venogenic disease the elastin in the veins starts to be destroyed and replaced with collagen (that is less elastic). This is like a sort of accelerating ageing. Some studies shows that transforming growth factor-B plays an important role in this damaging process of veins wall. Bad news is that elastin is of vital importance for the tunica albuginea. As venogenic patients have a general "elastin-collagen building disorder" the tunica albuginea will be attacked too. I'm not talking about peyronies plaque or so on. The less elastic tunica albuginea will suffer from subluxation and floppiness, and is going to have difficulties in compressing the sub-tunical and emissary veins of the penis. Moreover these veins are already altered in their structure because of the general venogenic disease. So this 2 factors together produce a venous leak.
In Peyronyie's disease occurs something similar in the tunica albuginea, but instead of subluxation and floppiness we can assist to the building of scar tissue/scar nodules in the tunica albuginea, which cause the penis to bend. Anyway scar tissue, or subluxation, or floppiness of the tunica have the same results: non-compliance of the tunica albuginea that causes venous leak.

What is the solutions? Well first of all the government should not allow Men or Women with venous disease to have children. Maybe this sounds crazy and kind of dictatorial regime, but no young man should suffer this sh*t and go through years of hell. The second solution could probably come from gene therapy, that should stop and reverse this "elastin-collagen building disorder".

Sorry if I made some grammar mistakes, I'm not a native speaker. I hope it was useful.

Regards

Hello!...first of all excuse my bad English. I know very little English and I am translating with google translate.

I was very interested in your answer. Although in my case I think something different happened to me. I have venous leakage approximately from 17-18 years of age. Now I am 48. With viagra, cialis, etc. I have correct erections. At least, I have that luck. Still, my sex life has been a big shit.

Like you, after reading many scientific articles recently, I came to the conclusion that my venous leakage problem was due to the loss of elasticity in the tunica albuginea. The structure of my tunic albúginea was damaged .... about that age of 17-18 years, I had the habit of masturbating in the shower with very hot water (too hot) and I once burned at the base of the penis with the penis in erection. The breaking temperature of the collagen structure is relatively low. The damage to the base of the penis are the most affecting in the mechanism of venous occlusion and I think that was my case. I can have a genetic basis also as you comment and a certain tendency to this problem, but after a lot of thinking, the appearance of my venous leakage problems coincide in time with this fact. I would like to know your opinion about it. Thank you very much for your analysis.

Richard

[Ricardo71]

Hello!...first of all excuse my bad English. I know very little English and I am translating with google translate.

I was very interested in your answer. Although in my case I think something different happened to me. I have venous leakage approximately from 17-18 years of age. Now I am 48. With viagra, cialis, etc. I have correct erections. At least, I have that luck. Still, my sex life has been a big shit.

Like you, after reading many scientific articles recently, I came to the conclusion that my venous leakage problem was due to the loss of elasticity in the tunica albuginea. The structure of my tunic albúginea was damaged .... about that age of 17-18 years, I had the habit of masturbating in the shower with very hot water (too hot) and I once burned at the base of the penis with the penis in erection. The breaking temperature of the collagen structure is relatively low. The damage to the base of the penis are the most affecting in the mechanism of venous occlusion and I think that was my case. I can have a genetic basis also as you comment and a certain tendency to this problem, but after a lot of thinking, the appearance of my venous leakage problems coincide in time with this fact. I would like to know your opinion about it. Thank you very much for your analysis.

Richard

[Lost Sheep]

What is the solutions? Well first of all the government should not allow Men or Women with venous disease to have children. Maybe this sounds crazy and kind of dictatorial regime, but no young man should suffer this sh*t and go through years of hell.

This sounds like using a blunt instrument to solve a problem without knowing for sure if it is necessary or even if it will work.

While I would not want any son of mine to suffer E.D., I certainly would not want ANY government bureaucrat imposing reproductive decisions on me and my wife. (I am not married, but the principle applies nonetheless.) This sounds disturbingly close to eugenics.

Respectfully submitted (in the hopes that this single paragraph was simply not thought through and reflection on my post might have an effect on the author and any readers).

[fredlund]

There has actually been some medical abstracts which suggest a physiologic link between bilateral varicocele and venous leak.

Screen Shot 2019-10-21 at 9.41.50 PM.png (462.59 KiB) Viewed 6645 times

These physicians suggest that there are actual communications between the penile veins and veins in the spermatic cord.

It seems likely there are numerous causes of "venous leak," more globally from defects in the tunica which may be acquired, or focal leaks from defective crural veins, arterio-venous malformations, or collaterals to varicoceles as these authors suggest.

[Robert66]

I have it all the huge viens back of leg the ed and the blue things on my feet first time i injected i used 32 units of 100 mcg pe1 and got the burn and a 10 min. Hard on now a year later i get an hour using 22 mcg of pge 1 so what changed? My doctor put me on daflon for my varicose viens and now i can walk much easier and get laid

[Depressed]

Hi guys
My inbox has been inondated with questions since I opened this post. I will give here a detailed explanation of what is causing the venous leak, in order to answer everyone who sent me a private message:

please do not misinterpret what I have said in the opening post: the cause of venous leak are not simply the veins, the cause of venous leak is a fibrotic degeneration of the erectile tissue caused by the genetic disorder in the construction of connective tissue. The fibrotic degeneration (i.e. Deterioration of elastine and susbtitution/repair with fibrotic tissue) can take place everywhere in the penis: in the tunica albuginea, in the intracavernous septum, in the intracavernous pillars or in the whole corpora cavernosa. The results is an erectile tissue that is less elastic and is no more able to activate the veno-occlusive mechanism, which consists in engorgement of the corpora cavernosa that press the subtunical venous plexus against the tunica albuginea and the tunica itself expands and closes the emissary veins (whic come out from the subtunical venous plexus and go out through holes in the tunica). The work of elastic corpora cavernosa and elastic tunica albuginea together provide the perfect veno-occlusion preventing the blood from leaving the corpora cavernosa. The perfect occlusion generate that “beautiful” sensation of pression in the penis which patents with venous leak cannot feel anymore. Unfortunately, when the fibrotic degeneration is in the first phase, usually it is not detectable through a penile doppler ultrasound, because the changes in the tissue are MICRO changes. In fact, if you whatch videos of penile implant surgeries (for example those of Dr. Kramer), some patients show surprisingly plaques and scars in their corpora only once the corpora are open and the surgeon tries to dilate them. And since in the first stage the fibrotic degeneration cannot be detected by normal diagnostic such as doppler ultrasound, vast majority of urologists will think patients have psicogenic Erectile dysfunction. Only in the aggressive phase of the degeneration the fibrosis is shown in a doppler ultrasound. Therefore, what I wanted to explain is that venogenic patients (with varicocele, varicous veins etc.) have a higher probability of developping this fibrotic degeneration at young age.

What is the solution? The only available definitive solution today is the penile implant. A future solution could probably come out from gene therapy, that should stop and reverse this "elastin-collagen building disorder".

[Simbarn]

="Depressed" the cause of venous leak is a fibrotic degeneration of the erectile tissue caused by the genetic disorder in the construction of connective tissue.

I think it would be naive to consider one singular cause to be the etiology of CVOD (corporal veno-occlusive dysfunction).

I would be interested to see where you have found this hypothesis regarding a “genetic disorder” that may be causing the fibrotic changes in the trabeculae of the corpus cavernosum and cavernosal arteries.
I have read many relevant studies on collagen deposition within the penile tissues and even the possible change in the collagen and elastin structure within the tunica albuginea, this has been researched quite significantly over the past 10-15 years.
What you have not mentioned, which is probably even more important, is the loss of smooth muscle. The actual replacement of smooth muscle with fibrotic tissue. You are quite correct, the penile erectile tissues are not as compliant when this occurs.
However, I have not read that a peculiar genetic disorder could be responsible, linked with varicose veins to cause this deterioration in the penis for some younger individuals.
What I have read numerous times in a number of papers is that these changes in the penis are most likely to occur from ischemia and therefore hypoxia. This can be related to a number of comorbid conditions such as low androgen levels, resulting in the deterioration of nocturnal erections and day time erections which help cause ischemia.
High cholesterol and increased oxidative stress are also strongly linked as is diabetes to fibrosis and smooth muscle loss.

If you have the studies/articles that demonstrate this genetic disorder and its link to penile fibrosis and varicose veins I would be interested to read them?
CVOD is a complicated condition. There are a number of causative factors that have been hypothesised to cause it, in fact anything that causes ED, will in my opinion result in occlusive function becoming dysfunctional.

Here are some of the major etiologies of CVOD:
Penile fibrosis
Smooth muscle loss
Adrenergic hyperactivity
Venous shunt
Congenital deformity
Atherosclerosis in the cavernosal and helicine arteries
Penile Neurological disorder
Compromised endothelial function and reduction in NOS (nitric oxide synthase)

It can be a complex mix of the above or any singular cause that can facilitate CVOD commonly termed as venous leakage. CVOD could be considered common as an end result of all erectile dysfunction causative factors. Simply because venous occlusion fails and blood can escape from the corpus cavernosum.

I think what you might have been trying to say in your post is that there “may” be a genetic disorder which can predispose some younger men to experience a form of CVOD due to fibrotic changes in the erectile tissue.

It is important if you are going to suggest a medical hypothesis, that you post the relevant scientific material or a link so we can read it too.

It is also important that other young members in the forum do not read your post and get convinced they need an implant if they discover they have a varicocele or evidence of varicose veins. It is very probable, that many people with varicose veins do not have any form of erectile dysfunction.