first injection is tomorrow.

[limpbiscuit]

Tomorrow I pick up a script of Tri-Mix and head to the urologist office for the first shot. The original worry has worn off, and now there is a sense of excitement to see how I will respond. I've been waking up with a nice chub for the last week, as my libido re-awakens. Will keep the list posted.

[Old Guy]

Good Luck. I remember my first injection and the hard on it gave me. Walking out of the office there was a cute female coming in. I noticed she glanced down and smiled. Wanted to jump her there and then.
Trimix worked for me for 4-5 years, then began to be questionable if it was going to work this time. Once it got to be it didn't work more times than it did, started looking at an implant.

[limpbiscuit]

Picked up the Tri-Mix today, and to answer anticipated questions, about 18 doses of the med, syringes, alcohol wipes and a box of sudafed cost about $160.00. The pharmacy was helpful with information about storage. It was frozen when I purchased it. Stored them in a tall cup of ice from the drive through.

Took the meds to the urologists office and we he gave me an orientation to using the medication. Use no more than twice per week, we are starting with a 10 unit starter dose, we will decide about increasing the dose based on response, and if we need to increase dose we step up in 5 unit increments. However I am to stick with the 10 unit dose for the first few injections.

The urologist coached me through the first administration... grasp the head, pull it taut, inject the dose along the shaft in a 1-3 or 9-11 orientation. And I laid the needle on the freshly cleansed skin, and pushed. And with a little force it went in up to the hilt. Injected the med and pull the needle back out. There was a little discomfort, but no significant pain and no blood.

And then The General reacted to the shot. Almost immediately the muscles in the penis relaxed and the whole thing got very chubby... a bit like a dog waking up an wanting to be scratched behind the ears. And there was a general feeling of activation in the penile tissues. Over the next 10-20 minutes it grew to about a 50% hardness. The shaft relaxed and my length that had been constrained by muscle tension was very evident. There it was flopped out for all to see, like a beached walrus.

The urologist came in and left several times to check progress. We spoke about how the shot was working, and he would leave for the process to continue. He checked about pain, and there was none except for a small sting from the shot.

All in all we wrapped up after about 30 minutes. The urologist said that the shot was successful, and that if I'd been home and in a more relaxing environment it probably would have produced a full erection. And we will continue with the 10 unit dose for the next two shots, and then advance possibly to 15 units. (I'm more inclined to advance to 12.5 however.)

One of my concerns is that I'm a grower not a shower, and The General is a tall one. So my former concerns about boner management while navigating the waiting room. I had feared having to walk through the crowd of grannies with a full mast, but that did not occur. Nevertheless, I had prepared by wearing a waist-length ski parka. And it was not necessary.

One of my remaining concerns is that the instructions for administering the shot are calibrated in milliliters, and the injection equipment is in units. Could members of the list weigh in and give some instruction in how to make the transition or calculation between the two measuring systems?

And oh, by the way, based on evidence there is no concern about a reappearance of the prostate cancer. We scheduled for one year out, and I was out the door.

[Growinjim]

Assuming you are using a 1 mL syringe, the units are in hundredths. So, the 10 unit mark is 0.1 mL

If the syringe is 0.5 mL, the range is from 0 to 50 and the 10 unit mark is still 0.10 mL.

[frwmw1]

Tomorrow I pick up a script of Tri-Mix and head to the urologist office for the first shot. The original worry has worn off, and now there is a sense of excitement to see how I will respond. I've been waking up with a nice chub for the last week, as my libido re-awakens. Will keep the list posted.

How did it go?

[bldoink]

It's good to hear things seem to be progressing nicely for you.

[limpbiscuit]

I've done a couple more injections at the 10 unit dosage. This gives about 75% hardness with good response to stimulation. Lasts about 30 minutes. I think it's time to increase the dose to 12.5 or 15 units. Will probably move to the lower dose first to keep it safe.
Do any of you other injectors notice less effect lying down as opposed to standing?

[Whodat]

Hummm....you might have a point there. Possibly standing has more effect. Will experiment and get back in a few weeks..
Good to hear you are having results. Going slowly is probably the best way.

[limpbiscuit]

And the injection experiment continues. I've done several more injections with diminishing results. My technique is good, no problem with injecting, sanitation or sharps disposal.

What I've decided is that since I have not kept the small vial of Tri-Mix frozen or refrigerated, it has lost its potency. Per the pharmacy the frozen mix is stable for 45 days, refrigerated is stable for 3 days, and at room temperatures it is stable for 45 minutes before losing effectiveness. I have kept the 5 main vials frozen, and have allowed the working vial to remain at room temperature.

I did buy a small insulin refrigerator off Amazon. That should be useful in keeping the current dose at cool temperatures, where it should remain at working strength for three days.

The Tri-Mix formulation is Alprostadil 8 mcg, Papaverine 22 mg, Phentolamine 0.8 mg / ml
I'm using 10-15 units and tapering up to find a stable useful dose.

And I have questions:

Which of the components of this brew are not shelf stable at room temperatures? Is there an alternative component?

I read on FT that others have different experiences with the shelf life of Tri-Mix kept at room temperature. I wonder if that is based on a different component of the mix?

In the future I want to explore using a version of Tri-Mix that is more stable at room temperatures. In the mean time the plan is to unfreeze one vial at a time and fill syringes wit 15 units. Freeze the filled syringes except for the one that I plan to use. How does that sound?

[bldoink]

Keep it refrigerated if not frozen. I would never keep it at room temperature due to potential bacteria growth concerns. The alprostadil will degrade rapidly at room temperature so your mix may have degraded substantially, especially as your mix has a fairly high alprostadil component for it's strength, which is pretty weak. Alprostadil is generally considered the most potent ingredient of tri-mix so removing it may be problematic. Alprostadil is usually only removed from the mix for guys that have unbearable side effects from it. When not traveling I have no difficulty keeping my mix frozen, all of it. However with the alprostadil removed the mix if pretty stable without much refrigeration.