Does bimix and PGE1(Alprostadil) have the risk of priapism as Trimix or its lower?

[Frenchie]

I want to try injections for my ED but here is the problem. I live in a small town in Europe and the only hospital in the city with ER is the hospital I work in so I sure as hell don't wanna go there if something bad happens. So thats why I want to avoid priapism at all costs. There is another hospital in the next city but I don't have a car so its not possible to go there if something goes wrong. What can I do to minimize the risk of priapism as low as possible? Would it be a good idea to tell the doctor to prescribe Phenylefrine?

[bldoink]

I haven't tried any internet information dives on that topic. I'd say the best way to avoid a priapism is to be very conservative when starting injections. Start with a very low dose, not expecting to produce a useful erection. Stay very conservative with your dose until you are sure your injection technique is very good. Then slowly titrate up to a dose that provides.

I'm concerned that some priapism events are a result of guys that don't have their injection technique perfected and increase doses looking for results and then suddenly hit the injection correctly with what is then an overdose and a resulting priapism. Start unnecessairly low. Consider it time well spent on practice. Then slowly increase doses until you get your desired result.

If your doctor will prescribe Phenylefrine then it would be nice to have on hand. At least have Pseudoephedrine on hand if available to you.

Read all of the old injection threads you can stand.

[computerguy]

I am going to look into this. I was extremely cautious with trimix, but found that the lowest does that produces the desired result tends to last dangerously close to the 4 hour mark. I would never inject it without having the injectable antidote on hand, and twice I had to use it. Fortunately it worked immediately. Will post back if I get to trying bimix.

[computerguy]

Bumping this up, because this question was asked on another forum, and someone recommended asking here. I also read reports from a few other guys, who like me end up with a close to 4 hour erection with just small enough dose to do the job.

I am not sure if the concentrations are "standard" but I was on 20/30/1 and just switched to 10/30/1 (trimix #5 ?), but have not tried it yet. I am hoping that cutting the alprostadil in half will help. Does that sound reasonable? If indeed bimix has lower incidence of priapism then I'd think so?

[Sean762]

Bumping this up, because this question was asked on another forum, and someone recommended asking here. I also read reports from a few other guys, who like me end up with a close to 4 hour erection with just small enough dose to do the job.

I am not sure if the concentrations are "standard" but I was on 20/30/1 and just switched to 10/30/1 (trimix #5 ?), but have not tried it yet. I am hoping that cutting the alprostadil in half will help. Does that sound reasonable? If indeed bimix has lower incidence of priapism then I'd think so?

Tri-mix T-105 is 10/30/1....but the ratio is not what you think. The 1 is a mcg (microgram) of Alprostadil....the main ingredient in the stack doing the work.

My understanding is the formulation is 1 mcg/ml.

Your 20/30/1 was 20mg (milligrams) of Papaverine, 30mg of Phentolamine, and 1mcg of Alprostadil....your new dose is listed the same way...so they cut the Papaverine down; not the Alprostadil.

So Tri-Mix T-105 is found here for the breakdown of what the 30/1/10 means (I was wrong above which is why I struck through it):

30 mg Papaverine; 1 mg Phentolamine; 10 mcg Alprostadil/PGE-1 (keep in mind the last one is in MICROGRAMS).

https://www.rxbuyersclubusa.com/pricing

I'm attaching a screen shot of the breakdowns for folks to reference.


Papaverine actually has a higher incidence of priapism than Alprostadil.....I did a long write up on this with Olympia Pharmacy...let me see if I can find it and link it.

[Sean762]

viewtopic.php?f=5&t=23914&p=227360#p227360

I updated the last post in the thread with the research I found. There's not a lot there about priapism (I was more focused on scarring/fibrosis caused by Papaverine)....but a couple of quotes said that Papaverine is more likely to cause priapism as well so the computerguy's doc reducing that component makes sense.

[computerguy]

Tri-mix T-105 is 10/30/1....but the ratio is not what you think. The 1 is a mcg (microgram) of Alprostadil....the main ingredient in the stack doing the work.

My understanding is the formulation is 1 mcg/ml.

Your 20/30/1 was 20mg (milligrams) of Papaverine, 30mg of Phentolamine, and 1mcg of Alprostadil....your new dose is listed the same way...so they cut the Papaverine down; not the Alprostadil.

Papaverine actually has a higher incidence of priapism than Alprostadil.....I did a long write up on this with Olympia Pharmacy...let me see if I can find it and link it.

Sean, thank you for the reply! I am looking at my new script, and it says: "30mg/ml Papaverine / 1mg/ml Phentolamine / 10 mcg/ml PGE1" so that sounds to me like it was the 20 of PGE1 cut to 10. Also from a medical study on dosages had "Each 1 cc of Trimix solution contains PGE1 at 10 ug/ml, papaverine at 30 mg/ml, and phentolamine at 1.0 mg/ml".

[Sean762]

Tri-mix T-105 is 10/30/1....but the ratio is not what you think. The 1 is a mcg (microgram) of Alprostadil....the main ingredient in the stack doing the work.

My understanding is the formulation is 1 mcg/ml.

Your 20/30/1 was 20mg (milligrams) of Papaverine, 30mg of Phentolamine, and 1mcg of Alprostadil....your new dose is listed the same way...so they cut the Papaverine down; not the Alprostadil.

Papaverine actually has a higher incidence of priapism than Alprostadil.....I did a long write up on this with Olympia Pharmacy...let me see if I can find it and link it.

Sean, thank you for the reply! I am looking at my new script, and it says: "30mg/ml Papaverine / 1mg/ml Phentolamine / 10 mcg/ml PGE1" so that sounds to me like it was the 20 of PGE1 cut to 10. Also from a medical study on dosages had "Each 1 cc of Trimix solution contains PGE1 at 10 ug/ml, papaverine at 30 mg/ml, and phentolamine at 1.0 mg/ml".

Well, I stand corrected. I had it completely backwards. Not sure what site I got that info from now....but clearly I was wrong. Apologies. I'll edit the post to correct the bad info.