Tolerance level with Trimix

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spikebites
Posts: 1
Joined: Fri Apr 05, 2024 7:48 pm

Tolerance level with Trimix

Postby spikebites » Tue Jun 11, 2024 12:32 am

Hi,

I just recently started trimix. I was started on the lowest dose, then bumped to 10/1/30. This dose still requires about 40-50 units and I am not staying hard for longer than 25 minutes and its only 60-70%. My doctor just bumped it up to 20/2/?.

My question is, will my tolerance keep going up? If i continue to use trimix, will I need to increase dosage as the years go by?

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bldoink
Posts: 4025
Joined: Mon Apr 03, 2017 12:58 am
Location: Fl.

Re: Tolerance level with Trimix

Postby bldoink » Tue Jun 11, 2024 12:55 pm

10/1/30 was fairly weak. The new mix should be a fair bit stronger. Wait and see how that does. No one knows in advance if you will have to adjust your mix frequently. Some guys remain stable for years. Others with rapidly progressing ED will have to adjust frequently. I've been on the same mix for quite a few years.
RRP 2011 Mayo Jacksonville, Dr. Wehle. Non nerve sparing. C in margins. Radiation 2023, V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ 7 - 16 units. Originally Edex20 or 40, then compounded PGE1 due to cost. Inject. 14 yrs. It works. FL Treasure coast.

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Stew52
Posts: 375
Joined: Fri Apr 13, 2018 4:22 pm
Location: Central TX

Re: Tolerance level with Trimix

Postby Stew52 » Mon Jun 17, 2024 5:18 pm

My mix strength and dose both increased over time in 7 1/2 years (30/1/20 @ 0.15ml to 40/4/80 @ 0.60ml, or just 80mcg PGE @ 0.60ml) but with a "multi-media" PT approach I have been able to significantly reduce it recently. Guardedly optimistic that I can play this out for many more years now. See post on Phoenix: viewtopic.php?f=5&t=24495
NOT an MD. 72, M52 yrs, CenTX US. Inj since 12/2016, a yr after pills stopped working. Caverject for a yr. 1/2018 Tri-Mix at 30 pap/2 phent/60 pge @0.3ml, now 0.5ml 80mcg/ml PGE1. DE/Anorgasmia setting in since 5/2019, worse now.

sogwap
Posts: 471
Joined: Wed Jul 20, 2011 8:10 am
Location: Ontario, Canada

Re: Tolerance level with Trimix

Postby sogwap » Tue Jun 18, 2024 8:27 pm

I've been using Trimix for just over two years.
I now use a lower amount than when I started injections two years ago.
Struggled with ED/PE for years.
Started using Trimix in May 2022 with very good results.


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