First human clinical trials on bioengineered cavernosa

The final frontier. Deciding when, if and how.
indeed
Posts: 128
Joined: Fri Sep 30, 2022 3:25 am

First human clinical trials on bioengineered cavernosa

Postby indeed » Tue Aug 06, 2024 2:37 am

Hey guys,

I found this study : https://www.medifind.com/articles/clini ... al/4524071 , https://ctv.veeva.com/study/bioengineer ... le-corpora

It's the first study i came across where they are implanting bioengineered corpora in humans.

Set to start in Jan. 2025 and ends in Oct. 2025.

I find this very exciting and thought it might be of interest to some of you

Cheers
30 years old. Suspensory ligament repair with Dr. Ralph March 23.
20cm Titan OTR, no RTEs. Dr. Clavell - May 10, 23.

Mark1974
Posts: 369
Joined: Wed Feb 15, 2023 5:16 pm
Location: Central Illinois

Re: First human clinical trials on bioengineered cavernosa

Postby Mark1974 » Tue Aug 06, 2024 3:42 am

It looks fascinating, but am I understanding correctly that they will need cadavers to construct each new penis?
Born 6/15/74. I have substantial venous leak with fairly severe hour-glassing, but no hard plaques. My urologist is sexual health expert Dr. Laurence Levine who performed a Doppler Ultrasound and diagnosed me with VL in 2020. I also have mild BPH

dan_bionic
Posts: 115
Joined: Wed Dec 13, 2023 5:50 am

Re: First human clinical trials on bioengineered cavernosa

Postby dan_bionic » Tue Aug 06, 2024 5:50 am

yes, there is a need of cadavers for each corpora cavernosa/albuginea.
It wii take ages until a pilot study becomes reality , but still a new promising begoning, however this has only a chance if the artificial implants were bad, but currently I see the implants on the market work very well and will get even better, like with new pump technologies and material that is used.

cheers
Dan
65, from Germany, 30 years of ED
Implant July 20th, 2023, AMS LGX 18cm plus 5 cm RTE
That was the best I could ever do and I should have done it much earlier.
How I use to inflate und deflate my penile implant

Mark1974
Posts: 369
Joined: Wed Feb 15, 2023 5:16 pm
Location: Central Illinois

Re: First human clinical trials on bioengineered cavernosa

Postby Mark1974 » Tue Aug 06, 2024 7:59 am

dan_bionic wrote:yes, there is a need of cadavers for each corpora cavernosa/albuginea.
It wii take ages until a pilot study becomes reality , but still a new promising begoning, however this has only a chance if the artificial implants were bad, but currently I see the implants on the market work very well and will get even better, like with new pump technologies and material that is used.

cheers
Dan

I think the difficulty of having a cadaver available for each penis would make it challenging to use this for standard erectile dysfunction.

I think this research is probably being used to look for potential treatments for people who have had injuries or disfigurements.

I don't see a biological alternative to implants on the horizon for some time ahead

And thanks for the video. I think it is useful. I will make one or two also after my implant, because it is helpful to men like myself looking to get the operation
Born 6/15/74. I have substantial venous leak with fairly severe hour-glassing, but no hard plaques. My urologist is sexual health expert Dr. Laurence Levine who performed a Doppler Ultrasound and diagnosed me with VL in 2020. I also have mild BPH

dan_bionic
Posts: 115
Joined: Wed Dec 13, 2023 5:50 am

Re: First human clinical trials on bioengineered cavernosa

Postby dan_bionic » Tue Aug 06, 2024 9:49 am

you are right with the cadaver it only makes sense for those who are having issues where artificial implants can't be used.

Yes, a video makes it easier to decide if one can see the results and how the implant is functioning.

Cheers
Dan
65, from Germany, 30 years of ED
Implant July 20th, 2023, AMS LGX 18cm plus 5 cm RTE
That was the best I could ever do and I should have done it much earlier.
How I use to inflate und deflate my penile implant

CigareVolant
Posts: 111
Joined: Wed May 25, 2022 6:13 pm

Re: First human clinical trials on bioengineered cavernosa

Postby CigareVolant » Tue Aug 06, 2024 3:37 pm

I'm curious which problems this would fix.

In my case, I don't think the problem was related to the cavernosa itself, but to the "blood plumbing." My hunch is that this wouldn't have been a solution for me. But I'm just guessing based on the limited information in the study request.
Implanted June, 2022 by Dr. Karpman. 22cm Titan with 1.5cm RTE.


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