using leftover caverject

[mlc2010]

Hello
my 5mcg caverject came today, it came with 1ml syringe, solution and powder. I mix the powder in the syringe, but I only want to use 2.5mcg, how much on a 1ml syringe should I draw in?

also, does the leftover need to be kept in fridge? there is conflicting reports on this

[dtwarren1942]

1/2 a syringe or 50 units will provide 2.5mcg. Refrigerate the remaining 50 units for a subsequent injection.

[mlc2010]

Well I did 2.5mcg and no reaction just the right side became more fuller. Should I up the dose to 5 tomorrow? Quite disheartened

[dtwarren1942]

I use Trimix which contains PGE1 -- 5.88mcg/ml. I inject 45 units which would be about 2.5 mcg of PGE1. However, Trimix also includes two other active ingredients.

Hopefully, Jstars will chime in. He is more familiar with stuff.

[Bluewhippet]

If you were being treated by an NHS Erectile Dysfunction Clinic they would start with either 2.5 or 5 mcg and gradually work the dose up until you get a result which gives you a firm erection lasting no more than one hour. The dose will depend on the severity of your dysfunction and your individual response to Alprostadil PGE1 (Caverject). In my case I have ED probably as a result of Type 2 diabetes. My first injection, like yours, gave little effect. I need between 20 and 25 mcg of Caverject to get a good result - 20 mcg gives me about 20 minutes and 25 mcg about 45 minutes firm erection. I will gradually become less firm and chubby for about another hour.

I have read some medical trial reports which record that the average dose needed in a trial of about 100 men was 21.7 mcg. If your ED is quite severe I am not surprised by your response. I used Viagra or Levitra for over 10 years until it became less effective (Cialis never worked for me). I have now used Caverject or Viridal for over 2 years successfully.

Refrigeration is essential for any left over. Best of luck - bear in mind that priapism is very rare using Caverject. If you have difficulty obtaining Caverject in the UK (sometimes unreliable supply) Viridal is exactly the same thing (Alprostadil PGE1) in other countries Edex is the alternative. Unfortunately, there appears to be no source for Trimix in the UK.

[mlc2010]

If you were being treated by an NHS Erectile Dysfunction Clinic they would start with either 2.5 or 5 mcg and gradually work the dose up until you get a result which gives you a firm erection lasting no more than one hour. The dose will depend on the severity of your dysfunction and your individual response to Alprostadil PGE1 (Caverject). In my case I have ED probably as a result of Type 2 diabetes. My first injection, like yours, gave little effect. I need between 20 and 25 mcg of Caverject to get a good result - 20 mcg gives me about 20 minutes and 25 mcg about 45 minutes firm erection. I will gradually become less firm and chubby for about another hour.

I have read some medical trial reports which record that the average dose needed in a trial of about 100 men was 21.7 mcg. If your ED is quite severe I am not surprised by your response. I used Viagra or Levitra for over 10 years until it became less effective (Cialis never worked for me). I have now used Caverject or Viridal for over 2 years successfully.

Refrigeration is essential for any left over. Best of luck - bear in mind that priapism is very rare using Caverject. If you have difficulty obtaining Caverject in the UK (sometimes unreliable supply) Viridal is exactly the same thing (Alprostadil PGE1) in other countries Edex is the alternative. Unfortunately, there appears to be no source for Trimix in the UK.

being that cialis works for me, I thought 2.5mcg would be enough, but alas not. I will try 5mcg, if your being treated on NHS, are you only allowed 4 per month?

[Bluewhippet]

Yes. If you have certain conditions, e.g. MS, diabetes, Prostate Cancer, heart problems etc, under the NHS you can be prescribed 4 doses of treatment for ED free each month. Otherwise you have to pay.

Although your doctor can prescribe the various pills – Cialis, Levitra Viagra he will not normally prescribe 2nd level treatment (Caverject or Muse) unless he has a recommendation from an NHS ED Clinic (he can refer you). They will give you increasing doses to determine the strength you need without having a hard erection the lasts more than 1 hour. In my case 20 to 25mcg (in my experience you will gradually get a softer and softer erection for about another hour). If you can get a prescription for 40mcg of Caverject (Alprostadil/PGE1) you can refrigerate (or freeze) any surplus. Refrigerated at 3degrees Centigrade it will not lose much strength in a week or 2, frozen it will remain potent for at least 6 months. I transfer the surplus to a sterile 100unit (!cc/1ml) 30g ½ inch Insulin syringe ( about 20p each if you buy 100) and refrigerate. These are more comfortable than the needles in the Caverject pack which are 29g – a bit thicker.

If you need more than 4 doses or do not qualify for a free prescription you will need a private prescription from your doctor but it is expensive – at least £17 for a single 40mcg vial of Alprostadil powder and sterile water. Incidentally, for those outside UK, Sildenafil Citrate (the generic version of Viagra) is out of patent and legally available in UK. That is what the NHS now prescribes and 4 X 100mg tablets can now be bought online with a prescription for about £8 ($13). I am not sure if they will ship overseas.

[JimStars]

Blue,

Instead of actually using those barbaric syringe/needles with Caverject you could also buy some 5ml sterile vials (empty) for a couple bucks and dump all of the caverject mixture in there. And you can keep reusing the vial as long as you keep it cold all the time .. even if empty. Then use some nice 30 or 31g needles that you have and draw out what you need etc -- adding more into the vial as needed to top it off.

J

[mlc2010]

Blue,

Instead of actually using those barbaric syringe/needles with Caverject you could also buy some 5ml sterile vials (empty) for a couple bucks and dump all of the caverject mixture in there. And you can keep reusing the vial as long as you keep it cold all the time .. even if empty. Then use some nice 30 or 31g needles that you have and draw out what you need etc -- adding more into the vial as needed to top it off.

J

caverject comes with 30g I think x

[Bluewhippet]

Caverject comes with 29g needles which are really not a problem but they only supply 40mcg in a vial to which you add bacteriostatic water from a syringe which is also in the kit. They provide 2 needles; a fairly thick needle to inject the water into the vial of dry powder and then, after mixing, use the large needle to draw out the required amount back into the syringe you then change to the 29g needle before injecting into your penis. Because Caverject availability in 40mcg doses is not good in UK I am usually prescribed Viridal which is exactly the same drug (alprostadil/PGE1) but comes as a dual chamber syringe similar to Caverject Impulse 10 and 20 mcg. This is much more convenient to use.but also uses a 29g needle. 30g needles are a bit more comfortable and I usually remove the plunger from a 30g 1/2 inch 100 unit insulin syringe (single use) sqiuirt in the amount I require (usually 25mcg) and use that. I then refrigerate the remaining 15mcg for future use. That way two 40mcg packs of Viridal (or Caverject) give me 3 injections. Since in UK we only get four doses per month free under our NHS, I can get 6 injections out of the 4 doses.