Trimix strength

[alan46]

What is the amount of trimix needed to get fully erect based on? The size of the penis?

[tomas1]

I think (but don't know) it's an individual thing and not based on penis size.

[ocitgo]

This may help

http://www.ncbi.nlm.nih.gov/pubmed/7966797

The lowest effective dose of prostaglandin E1 as treatment for erectile dysfunction.
Chen J1, Godschalk M, Katz PG, Mulligan T.
Author information
Abstract
The recommended dose of prostaglandin E1 as treatment for erectile dysfunction has been reported to be 10 to 40 micrograms. However, adverse effects probably increase with increasing doses. We conducted a prospective, single-blind, dose-escalating study of prostaglandin E1 on 20 men with erectile dysfunction of various etiologies. The response to prostaglandin E1 was assessed by penile palpation and RigiScan rigidity monitoring. A total of 17 patients completed the study: 1 achieved rigidity with 1 microgram., 2 with 2 micrograms. and 4 with 3 micrograms. prostaglandin E1, while more than 70% achieved rigidity with 5 micrograms. or less and more than 80% had a full erection with 20 micrograms. Of 138 injections there were 2 episodes of pain after injection. We conclude that the often recommended starting dose of 20 micrograms. is too high. A more appropriate starting dose is 2.5 micrograms. with increments of 2.5 micrograms. until the lowest effective dose is achieved. This approach may lessen the major impediments to prostaglandin E1 use, that is burning and pain.

"A total of 17 patients completed the study:

1 achieved rigidity with 1 microgram.,
2 with 2 micrograms. and
4 with 3 micrograms. prostaglandin E1,
70% achieved rigidity with 5 micrograms. or less and
+80% had a full erection with 20 micrograms"

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My dose of Prostaglandin is 10MCG/ML with less than full erections.

My 1st and last Trimix dose
Papaverine 30
Phentolamine 1
Prostaglandin 10 (I will ask the my next refill to be increased to 20)

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This week I picked up my new prescription as below
Papaverine 30
Phentolamine 2
Prostaglandin 20

I started 20 ml. Next with 30 or 40 ml. 20 works but I need more

[ocitgo]

This is an interesting report on Trimix strength. They used rabbits in part of their testing

http://link.springer.com/article/10.100 ... 593#page-2

Prostaglandin E1 (PGE1) is a naturally occurring substance that is present in a variety of mammalian tissues, including the semen of fertile men. Its use in the diagnosis and treatment of erectile dysfunction has been extensively studied. In doses of 10–20 μg, PGE1 produces full erections in 70–80% of patients with erectile dysfunction. In diagnostic use PGE1 is employed as a simple office test and in conjunction with various hemodynamic tests. Self-injection of PGE1, either with the patient or his partner administering the injection, is a minimally invasive and effective treatment for erectile dysfunction in patients with organic or psychogenic erectile dysfunction. Its use is contraindicated in patients with sickle cell anemia, severe coagulopathy, schizophrenia or severe psychiatric disorder, poor manual dexterity, severe venous incompetence, or severe systemic disease. As calculated from data in the published literature, the most frequent side effects are pain at the injection site or during erection (occurring in 16.8% of patients), hematoma/ecchymosis (1.5% of patients), and prolonged erection/priapism (1.3% of patients). The potential for prolonged erection/priapism, the most serious side effect, can be minimized by careful titration of the dose and through patient education. Systemic side effects occur rarely during PGE1 use. During extended use, patients should be monitored for potential long-term side effects, such as fibrosis and angulation.

[ocitgo]

These are the 2 common prescriptions. I recently started the 2nd. There is a local pharmacy in Poulsbo WA. http://www.cascaderx.com/. $190

https://empower.pharmacy/drugs/tri-mix-injection.html

[Cigar56]

Hi Octigo,

I also PM'ed you on this: I see you moved up to a 30-2-20 formula from 30-1-10. I'm planning to make that same move. If I can ask, what difference did you notice from the stronger formula?

Thanks,

Cigar

[ocitgo]

Hi Octigo,

I also PM'ed you on this: I see you moved up to a 30-2-20 formula from 30-1-10. I'm planning to make that same move. If I can ask, what difference did you notice from the stronger formula?

Thanks,

Cigar

I have tried 30 units and next will be 40. I am slow at testing and waiting for an opportunity at the 40 level. At my age, my 52 yr love affair has little room for impatience. I have ED for the last 24 yrs since I had a bone marrow transplant for leukemia. I could have use Tri-Mix back then but didn't know about it and thought I would get back my moxie much sooner. Worse yet having a TURP 4 years ago set me back more than ever. Viagra worked for a few years but not now. I still have hope with Tri-Mix.

[tigerbw]

I asked my uro for a stronger trimix and he refused at the beginning.
My current trimix is 30mgPAP/30mcgPGE1/0.6Phent
He mentioned that he could not go higher on Papaverine and increasing Phentolamine could dangerous lower my blood pressure. I finally ask him to increase my Pge-1 to 40mcg which he agreed but mentioned that the highest he would go and my next step would be a penile implants.
What do you think?
Thanks for any input.

[RockyinNM]

Hi all,
Thought I would give an update--
I started out on bi-mix--OK for 6mo.--then moved to tri-mix, started out very low dosage strength, 30-2-10--then went to 30-2-20, then to 30-2-40---now at 30 2 -80, doing 50 units, on all the other scripts I would start low on the units, and have to increase upwards of a 100 units.
Right now doing the 30-2-80 is OK--but think I may ask for the strongest of 30-2-120---I do not like having to do so many units.

My ED is caused by age 73, plus, blood pressure, blood thinners, ect--U get the idea.
Rocky

[Willgp]

Hello,
New to this. DId my first injection after research without office visit with no issues. Got a 15 min acceptable for masturbation with the wife with the first try. Injected .20cc Going to double it next try. The strength on my script list this:
Alprostadil 5.6 mcg
Phentolamine .56 mg
Papaverine 16.7mg

Should I try another uro to get a stronger script? This seems weak compared to others in this thread.

Good luck to all. Been a rocky road to get to this point for me. Never thought good old willy would go south on me.

Will