About to take the plunge!

[NolaVette]

I decided to increase the dosage to .3ml instead of .4ml just to be cautious and take it slow. I got nothing this time. Not a hint of an erection. I might as well have injected plain water. I hope it's just a case of not hitting the right spot. I store the Papaverine in the refrigerator even though it can be kept at room temps below 78 degrees. Does anyone know if storing it in the fridge would affect strength. I made sure to allow it to adjust to ambient temp before injecting. The info sheet that comes with the Papaverine says nothing about not refrigerating it.
One other thing-I injected last time into the right side it worked but this time I injected into the left side which did not produce any results. Anybody have a situation where one side works better than the other?

Steve
NolaVette

[antelope]

Steve,

Sorry to hear you had a "fail". I've had just 1 in a whole year of shooting Trimix. I still don't know what happened.

I have found no difference in results between shooting left and shooting right; nor have I heard that mentioned before. Someone might chime in to the contrary, but the anatomy of the penis suggests strongly that right/left shouldn't matter. My uro and my pharmacist told me to keep my trimix in the fridge. I inject it cold and cannot feel the cold liquid inside Little G. I can't think of a reason to let it come to room temperature. But again, someone with more knowledge of the chemistry might shed some light on that.

Frankly, my best guess is that you just missed the sweet spot. It actually took me a a little practice to be able to use the needle with my left hand. Besides being naturally right-handed, I'm something of a klutz. So if there's difference between left and right, that may be it.

Try again and don't hesitate to inch up the dosage. Best wishes for hard times!

Greg

[Muz061]

Steve,

I'd reiterate what Greg said. I have had decreased affect from a syringe made up and stored which I had left unrefrigerated for a few hours. I have had one shot that missed the zone - the resistance in teh syringe alerted me something wasn't right and I ended up with a broad bruising.

I know the uros stress the risk of priapism but i have found a wide zone of effectiveness from 0.9ml to 1.5ml, with rigity and duration both increasing with the dose. 0.9ml is marginal rigidity and less than an hour while 1.2 is hard but needs ongoing stimulation up to 2 or 2.5 hours. 1.5ml is starting to be the outer region of safe duration and very hard to the point of painful. I say this to encourage you to bump the dose by at least 50% over what was ineffective. I must have a more diluted trimix because the amounts stated are in ml or cc.

If you are reasonably sure you have injected right (the resistance to the needle should noticeably reduce before the syringe is fully inserted) whack up the amount in my opinion. Trimix should be highly effective as long as you don't have chronically bad venous leakage. If you were able to have some manner of erection before surgery you should certainly get it with this stuff, I am getting far better erection quality than pre operation.

[NolaVette]

Hey guys,
The stuff I'm using right now is Papaverine alone. It doesn't require refrigeration but you're supposed to keep it below 77 degrees. I've been keeping it in the fridge thinking it will last longer (shelf life). I was wondering if keeping it a lot cooler than 77 degrees might weaken the stuff causing the total failure after it worked 2 days earlier. But then, it was cold the time it worked also. Gonna have to wait till Saturday to try again. I'm using an Autoject II so I'm not able to feel how much pressure it takes to push the plunger since it does that automatically. Using a 1/2 inch needle. I was also wondering if a half inch might be too long for a very limp dick causing it to inject in the wrong place. But then the 2 times I tried the caverject I definitely hit the right spot and 100% results for over an hour each time, but with terrible pain which is why I've switched to Papaverine. Sorry to ramble so much.

Steve
NolaVette

[Muz061]

Steve,

Just read through your posts here. I think you need to look elsewhere for your meds. Papaverine is just one of the ingredients in Bimix and Trimix. Phentolamine is the second (bimix) and prostaglandin (the painful one) is included in small proportions in Trimix.

I had weak response with bimix (little better than cialis) so I can't imagine how papaverine would have raised a quiver in my old fella. I don't have the proportions of the trimix ingredients (they seem to regard it as their well guarded secret) but I think you need to find a mixing pharmacy who will supply you if that's what your team are sending you home with.

Getting your thinking around the needle is enough for many of us without having an ongoing battle with your specialists to provide you the known effective TRIMIX. Some specialists seem to have the idea that dispensing is about what they want to do - not about serving your needs! This is why forums are so valuable because of the inconsistency of quality in "health providers". I have had plenty of anger about poor information and lack of informed choices offered so I can sympathise. In my humble opinion you need to specify Trimix, Trimix, Trimix or you go elsewhere. There's plenty of history on this and other sites of the effectiveness of this wonder shot. IMHO you will go nowhere with single drug and in all probability Bimix. The reports of bimix here and elsewhere is well below 50% successful but it is pain free. Trimix is well over 50% successful and can carry some mild pain which most find easily tolerable.

I do want to encourage you to take control of your life. I got useless advice from "the best in the business" uro from pre operation until 6 months ago. i should have been on Trimix over 3 years ago and I would likely be now able to rely on cialis. That is still my aim but the delays and disappointments make that a lot less certain. If you had erections before your surgery I see no reason why trimix won't work incredibly well for you. I know from your posts you are cautious and I can understand that. If you continue to have poor experience with injection therapy it is likely you will give up where you could have succeeded. I can't encourage you more to demand Trimix, the most effective ED medication for most PCa surgery "victims".

[dtwarren1942]

First, help me with the ml/unit conversion. As a diabetic, I am accustomed to dealing in units. I have a 5 ml vial of Trimix which will fill 5 one hundred ml syringes so I am assuming one ml is equal to one hundred units. Is that right? If it is a 1:100 conversion, than 1.5 ml would be 150 units which seems very high to me unless it is a weak mixture. My Trimix includes 18 mg/ml of PGE-1. Is this approximately what most of us are using?

Second, I normally keep my Trimix refrigerated, I use it directly out of the frig , and it has always worked well, too well sometimes. Starting last week, I was able to reduce my dosage to 10 units and still had a 1.5 hour erection. This morning I was not sure my wife was in the mood so I decided to use 10 units from a two month old vial which had been stored at room temp. Turns out she was in the mood and I was able to keep her happy with a one hour erection. However, it did start to fade a bit before my usual 1.5 hour limit. The quicker fading could have been a result of the old Trimix or could be because of the recently reduced dosage. Next time I use 10 units of the refrigerated Trimex, I will have a better comparison.

[Cajun Jeff]

10 units works perfect for me.

Cajun Jeff

[antelope]

Here's the simple way to remember it:

100 units = 1 cc = 1 ml

Therefore:

50 units = 0.5 cc = 0.5 ml

Therefore:

5 units = 0.05 cc = 0.05 ml

Anecdotal evidence suggests that starting dosage is often somewhere between 0.3 ml and 0.5 ml or 30 to 50 units. My uro started me on 30 units; as it happend, that was way too high. (Short dick does have that advantage. lol) After a year of regular usage, I'm down to 2 units or 0.02 ml per bingo.

Happy hard times,

Greg

[NolaVette]

Muz,
Once I've jumped through all the hoops I'll probably end up with tri-mix. Although it would have to be a formula with a very low PGE1 level. I could handle a little bit of achiness if that would be the trade off for consistent results you guy seem to get with Tri-mix. Good thing is I'm only 3 months post-op and I have gotten a few erections in that time so I should be in no danger of penile atrophy. I had no problems whatsoever before surgery. So at this point it's all about titration of the correct drug.
The info concerning syringe measurements should be a sticky post. I had a little trouble learning it myself since I've never had any exposure to this kinda thing. I've seen some wildly inaccurate dosage measurements in some of the postings I've read. I'd hate to see a newbie using 10 or 100 times what they meant to use.

Steve
NolaVette

[dirtfrmr]

welcome, probably the best is to ask the pharmacist, as they will be really helpful
a better understanding of the math I did and got better results.
they were understanding and patience

best of luck
it is a cloudy world out there
and people don't seems to tell all
here people are different and it helps

dirtfrmr aka golfer who is always in the dirt rather than the grass


dirtfrmr