I have been studying various approaches to resolving anorgasmia and would like to hear and discuss what others have found. Cabergoline is a drug that has had a little success, but its potential side effects are pretty nasty. I'm currently researching other substances including Oxytocin.
Anyone with any information, feel free to participate.
I am an herbalist and natural health practitioner
BigEyes
Anorgasmia (Failure to achieve orgasm)
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Anorgasmia (Failure to achieve orgasm)
Doctor of Naturopathy (N.D.) and Herbalist. ED and occasional Anorgasmia from perineal surgery for rectal cancer Dec. 2012
Re: Anorgasmia (Failure to achieve orgasm)
First let me say that I have found that the PDE5 inhibitors can contribute significantly to anorgasmia. I believe this is true for many men, but certainly not all. But for those affected in this way, easing up on the Viagra, Cialis, etc., might help. Cockrings can also have that effect. In both cases, it may be something like being too hard so that the nerves are temporarily deadened somewhat. Just guessing about that.
I am in the process of getting a prescription for Apomorphine 4mg sublingual troches. Apomorphine is a dopamine agonist as is Cabergoline, but with a much shorter period of action, like 1-2 hours. So it would be taken "as needed" just before sex. A compounding pharmacy would be needed to make up the troches. My pharmacist will charge me about $100 for 30 troches or lozenges. Apomorphine was the active ingredient in the ED drug Uprima, which is no longer made. Most of the discussion of Apomorphine I have seen relates to erectile benefits, but it should also help with anorgasmia. Anyway, I should shortly be able to report my experience with it.
My pharmacist said that what they mostly prepare these days is a combination troche of either Sildenafil or Tadalafil together with Oxytocin.
I would think that either Oxytocin or Apomorphine should have some potential to help with anorgasmia, but the most effective might vary with the individual. The advantage of Cabergoline is that it reduces prolactin, high levels of which are believed to be the proximate cause of anorgasmia. But I think you would be on it continuously long term, which increases the potential for adverse effects, whereas the other two would just be taken as needed, and would wear off pretty quickly.
I am in the process of getting a prescription for Apomorphine 4mg sublingual troches. Apomorphine is a dopamine agonist as is Cabergoline, but with a much shorter period of action, like 1-2 hours. So it would be taken "as needed" just before sex. A compounding pharmacy would be needed to make up the troches. My pharmacist will charge me about $100 for 30 troches or lozenges. Apomorphine was the active ingredient in the ED drug Uprima, which is no longer made. Most of the discussion of Apomorphine I have seen relates to erectile benefits, but it should also help with anorgasmia. Anyway, I should shortly be able to report my experience with it.
My pharmacist said that what they mostly prepare these days is a combination troche of either Sildenafil or Tadalafil together with Oxytocin.
I would think that either Oxytocin or Apomorphine should have some potential to help with anorgasmia, but the most effective might vary with the individual. The advantage of Cabergoline is that it reduces prolactin, high levels of which are believed to be the proximate cause of anorgasmia. But I think you would be on it continuously long term, which increases the potential for adverse effects, whereas the other two would just be taken as needed, and would wear off pretty quickly.
Re: Anorgasmia (Failure to achieve orgasm)
I'm sorry but I don't have a great answer for you. The Anorgasmia topic has been brought up a number of times in the past. I don't recall there being any super miracle cure although several solutions are said to have helped. Try entering anorgasmia in the search bar from the Board Index page. You will get a bunch of hits. Some will be about herbs and/or supplements. Actually I think I saw a few from you on the topic from a couple of years ago.
A method I tried with some success is the Death Grip Cure designed as an aid for those engaged in excessive masturbation. Excessive masturbation wasn't my issue but the program does seem to help encourage a return of sensitivity and subsequently alleviate, at least somewhat, anorgasmia.
A couple of threads that mention that topic:
http://www.franktalk.org/phpBB3/viewtopic.php?f=5&t=9790&hilit=anorgasmia
http://www.franktalk.org/phpBB3/viewtopic.php?f=3&t=8875
Link relating to the above listed links: http://curedeathgrip.com/plan-fleshlight.html
There are also several links on the topic in the Documents Worth Reading List: http://www.franktalk.org/phpBB3/viewtopic.php?f=3&t=9266
Good luck.
A method I tried with some success is the Death Grip Cure designed as an aid for those engaged in excessive masturbation. Excessive masturbation wasn't my issue but the program does seem to help encourage a return of sensitivity and subsequently alleviate, at least somewhat, anorgasmia.
A couple of threads that mention that topic:
http://www.franktalk.org/phpBB3/viewtopic.php?f=5&t=9790&hilit=anorgasmia
http://www.franktalk.org/phpBB3/viewtopic.php?f=3&t=8875
Link relating to the above listed links: http://curedeathgrip.com/plan-fleshlight.html
There are also several links on the topic in the Documents Worth Reading List: http://www.franktalk.org/phpBB3/viewtopic.php?f=3&t=9266
Good luck.
R.R.P 2011 Mayo Jacksonville, Dr. M. Wehle. Not nerve sparing. C in margins. Radiation 2023, V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ 8 - 14 units. Originally Edex20, then compounded PGE due to cost. Inject. 12 yrs. It works. Treasure coast of FL.
Re: Anorgasmia (Failure to achieve orgasm)
Bldoink
Yes you are right. There are several entries about Anorgasmia posted in Franktalk, some by me a few years ago. I'm am looking for guys that have tried any natural substance that has helped, or any substance (natural or otherwise) that has helped or worsened the issue.
Many of the entries in Franktalk are about fleshlght, a commercial product designed to aid in masturbation. It is essentially an artificial vagina and may help a bit, but I don't think it is the answer.
Since many of my clients are suffering from Anorgasmia, I have recently increased my effort to find a reasonable solution that does not completely empty the wallet.
I will be posting more in this forum, so stay tuned.
BigEyes
Yes you are right. There are several entries about Anorgasmia posted in Franktalk, some by me a few years ago. I'm am looking for guys that have tried any natural substance that has helped, or any substance (natural or otherwise) that has helped or worsened the issue.
Many of the entries in Franktalk are about fleshlght, a commercial product designed to aid in masturbation. It is essentially an artificial vagina and may help a bit, but I don't think it is the answer.
Since many of my clients are suffering from Anorgasmia, I have recently increased my effort to find a reasonable solution that does not completely empty the wallet.
I will be posting more in this forum, so stay tuned.
BigEyes
Doctor of Naturopathy (N.D.) and Herbalist. ED and occasional Anorgasmia from perineal surgery for rectal cancer Dec. 2012
Re: Anorgasmia (Failure to achieve orgasm)
Morgan
There are several reports about ED drugs inhibiting orgasms. It seems to be very individual affecting a small to medium group of men.
A retaining ring on the penis, especially if used after an erection from a VED (Vacuum Erection Device) can also cause problems. In either case, this is primarily due to the ring constricting blood flow to the penis, especially in the case of the VED. Poor blood flow, particularly after 10 min or more, causes nerves to become insensitive. Think "pins and needles" in a fallen asleep limb.
Apomorphine and Cabergoline are, as you mention, dopamine agonists, Which essentially means they increase dopamine levels in the body. Both have some nasty side effects. I would prefer using Mucuna Puriens, an herb known to increase dopamine levels with far fewer side effect.
As far as a combination troche of either Sildenafil or Tadalafil together with Oxytocin, I doubt there would be any real benefit to that since oxytocin is poorly absorbed sub-lingually.
High prolactin levels do certainly influence Anorgasmia and can possibly be lowered with B-Vitamins (particularly B6) as well as zinc.
I am working on trying to find a combination of vitamins, herbals, and peptides that might help resolve Anorgasmia. Feel free to contact me via this board or privately if you have anything to contribute or just want to chat about this. My phone and email address is in my profile.
BigEyes
There are several reports about ED drugs inhibiting orgasms. It seems to be very individual affecting a small to medium group of men.
A retaining ring on the penis, especially if used after an erection from a VED (Vacuum Erection Device) can also cause problems. In either case, this is primarily due to the ring constricting blood flow to the penis, especially in the case of the VED. Poor blood flow, particularly after 10 min or more, causes nerves to become insensitive. Think "pins and needles" in a fallen asleep limb.
Apomorphine and Cabergoline are, as you mention, dopamine agonists, Which essentially means they increase dopamine levels in the body. Both have some nasty side effects. I would prefer using Mucuna Puriens, an herb known to increase dopamine levels with far fewer side effect.
As far as a combination troche of either Sildenafil or Tadalafil together with Oxytocin, I doubt there would be any real benefit to that since oxytocin is poorly absorbed sub-lingually.
High prolactin levels do certainly influence Anorgasmia and can possibly be lowered with B-Vitamins (particularly B6) as well as zinc.
I am working on trying to find a combination of vitamins, herbals, and peptides that might help resolve Anorgasmia. Feel free to contact me via this board or privately if you have anything to contribute or just want to chat about this. My phone and email address is in my profile.
BigEyes
Doctor of Naturopathy (N.D.) and Herbalist. ED and occasional Anorgasmia from perineal surgery for rectal cancer Dec. 2012
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- Joined: Mon Apr 03, 2017 3:07 pm
Re: Anorgasmia (Failure to achieve orgasm)
Thanks Big Eyes! I once posted some info and invited comments on anorgasmia, which at the time, maybe a year after I started using injections with Alprosdadil was an issue for me. All my uro could offer was "it's all in your head, just try not to think about it". We both laughed at my response to him which was "easy for you to say". But unfortunately many other men reported back with similar non-response from their urologists. Since then I've done much better, with very vivid orgasms maybe once for each 4 or 5 tries, either by way of sex with my wife or solo masturbation. Two things that have helped me were: 1. what my uro said... I try to relax, enjoy being "in the moment" feeling pleasure, enjoying it for its own sake. And 2. Using a smaller dose of medication down to 10 to 12 units on the syringe. Highr doses were having a numbing effect it seemed. I'd work my way up to 16 to 18 units over 3 years time. Now I am back up to that level but do feel full sensation, if not an orgasm every time or even close to it. a third method my wife and I have used with some great success is to stop and rest when my penis goes soft, (which it never used to with the injections, often for 2 to 3 hours), then rest for 15 to 30 minutes or more and start again, usually with oral on me with a flexible cock ring to support my next erection which almost always leads to a wonderful orgasm for both of us. Would love to get back to previous reliability of durable erections and reliable orgasms too. anything you discover will be most welcome by many FT guys . thanks again. you both seem to be knowledgable ! Look forward to progress reports!!!
Injections for 5 years PGE-1 (Alprostadil) 40 mcg /ml. Trying Tri Mix (20-2-30 . Hope is shift in meds will restore some sensitiviy. Enjoy sharing openly withother "EDguys". Love the site, informative and entertaining too!
Re: Anorgasmia (Failure to achieve orgasm)
Hey GoodWood:
Thanks for the KUDO's. One of the causes of Anorgasmia is that guys inject is too much chemical. More is definitely not better! I have found with both myself and clients, that more PGE1 than needed to cause a good erection inevitably leads to Anorgasmia with some guys. Once you have a dose that gives you a decent erection and lasts long enough, increasing the quantity increases duration of the erection but does nothing for its quality and sometimes causes Anorgasmia. For me, with a high enough dose, I can almost guarantee Anorgasmia no matter how much stimulation.
Many medical docs use "it's all in your head, just try not to think about it" as an excuse when they have no answers. They are taught in med school to be confident and always have an answer. If there is no drug or protocol in the PDR database, they, like much of our population, cannot think "outside the box!"
For example; In lieu of injections, PGE1 can be inserted directly into the urethra. In most cases, this will result in a decent erection in a more palatable, safer (and less expensive) way. However, from both personal and client's feedback, several urologists have said with firm conviction that this won't work. I and others have been using this technique successfully for a long time.
For many guys, an erection is the holy grail. They often do not realize they can have a mind-blowing orgasm without being hard. Sensitivity in the penile nerves is what determines the length and pleasure of the orgasm and has little to do with the extent of erection. Brain chemicals play a big part in this.
Anorgasmia, in my opinion, is partly caused by an imbalance of brain chemicals. For example; A deficiency in dopamine seems to cause it, and, it is a well-documented that high levels of either SHBG or Prolactin can be responsible as well.
My approach, for both my clients and myself, is to try to figure out what items might be out of balance and possibly responsible for the issue, bring them back into balance, and then record the results. Since each person's experience is unique, this takes a lot more time than a urologist (or any other medical doc short of a researcher) is willing to invest.
BigEyes
Thanks for the KUDO's. One of the causes of Anorgasmia is that guys inject is too much chemical. More is definitely not better! I have found with both myself and clients, that more PGE1 than needed to cause a good erection inevitably leads to Anorgasmia with some guys. Once you have a dose that gives you a decent erection and lasts long enough, increasing the quantity increases duration of the erection but does nothing for its quality and sometimes causes Anorgasmia. For me, with a high enough dose, I can almost guarantee Anorgasmia no matter how much stimulation.
Many medical docs use "it's all in your head, just try not to think about it" as an excuse when they have no answers. They are taught in med school to be confident and always have an answer. If there is no drug or protocol in the PDR database, they, like much of our population, cannot think "outside the box!"
For example; In lieu of injections, PGE1 can be inserted directly into the urethra. In most cases, this will result in a decent erection in a more palatable, safer (and less expensive) way. However, from both personal and client's feedback, several urologists have said with firm conviction that this won't work. I and others have been using this technique successfully for a long time.
For many guys, an erection is the holy grail. They often do not realize they can have a mind-blowing orgasm without being hard. Sensitivity in the penile nerves is what determines the length and pleasure of the orgasm and has little to do with the extent of erection. Brain chemicals play a big part in this.
Anorgasmia, in my opinion, is partly caused by an imbalance of brain chemicals. For example; A deficiency in dopamine seems to cause it, and, it is a well-documented that high levels of either SHBG or Prolactin can be responsible as well.
My approach, for both my clients and myself, is to try to figure out what items might be out of balance and possibly responsible for the issue, bring them back into balance, and then record the results. Since each person's experience is unique, this takes a lot more time than a urologist (or any other medical doc short of a researcher) is willing to invest.
BigEyes
Doctor of Naturopathy (N.D.) and Herbalist. ED and occasional Anorgasmia from perineal surgery for rectal cancer Dec. 2012
Re: Anorgasmia (Failure to achieve orgasm)
BigEyes wrote:Hey GoodWood:
Thanks for the KUDO's. One of the causes of Anorgasmia is that guys inject is too much chemical. More is definitely not better! I have found with both myself and clients, that more PGE1 than needed to cause a good erection inevitably leads to Anorgasmia with some guys. Once you have a dose that gives you a decent erection and lasts long enough, increasing the quantity increases duration of the erection but does nothing for its quality and sometimes causes Anorgasmia. For me, with a high enough dose, I can almost guarantee Anorgasmia no matter how much stimulation.
Many medical docs use "it's all in your head, just try not to think about it" as an excuse when they have no answers. They are taught in med school to be confident and always have an answer. If there is no drug or protocol in the PDR database, they, like much of our population, cannot think "outside the box!"
For example; In lieu of injections, PGE1 can be inserted directly into the urethra. In most cases, this will result in a decent erection in a more palatable, safer (and less expensive) way. However, from both personal and client's feedback, several urologists have said with firm conviction that this won't work. I and others have been using this technique successfully for a long time.
For many guys, an erection is the holy grail. They often do not realize they can have a mind-blowing orgasm without being hard. Sensitivity in the penile nerves is what determines the length and pleasure of the orgasm and has little to do with the extent of erection. Brain chemicals play a big part in this.
Anorgasmia, in my opinion, is partly caused by an imbalance of brain chemicals. For example; A deficiency in dopamine seems to cause it, and, it is a well-documented that high levels of either SHBG or Prolactin can be responsible as well.
My approach, for both my clients and myself, is to try to figure out what items might be out of balance and possibly responsible for the issue, bring them back into balance, and then record the results. Since each person's experience is unique, this takes a lot more time than a urologist (or any other medical doc short of a researcher) is willing to invest.
BigEyes
I heard that a lot of times it is due to dehydration as well.
Larry
Re: Anorgasmia (Failure to achieve orgasm)
Larry:
Never heard of that one, but nothing surprises me any more!
BigEyes
Never heard of that one, but nothing surprises me any more!
BigEyes
Doctor of Naturopathy (N.D.) and Herbalist. ED and occasional Anorgasmia from perineal surgery for rectal cancer Dec. 2012
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- Joined: Tue May 08, 2018 2:57 pm
- Location: South Central Indiana
Re: Anorgasmia (Failure to achieve orgasm)
I've had this problem to varying degrees for some years, well before I got implanted. I think it is related to several things: my penis seems to need more stimulation the older I get; in intercourse, my wife having had three children and being many years post-menopause, is not tight; she also is somewhat plump (very pleasingly so, don't get me wrong!) and me, having only been average length before implant and having lost the usual post implant 1 to 1-1/2 inches, cannot "reach in" as fully as previously; I masturbate quite a bit now since I crave sex and my wife is good with once a month if that now; and finally, it does get into my head sometimes. I've found a few simple adjustments which have helped. Firstly, I don't masturbate as much as I was doing soon after implant. When I do, I can tell right away that there is more stimulation and feeling and a quicker buildup. Secondly, when masturbating, I take it easier, resting my hand often, taking in the material I'm viewing or reading more fully, going back to stroking, back to rest, etc. Thirdly, and somewhat related to the second, I've slowed down a bit during intercourse, not worrying so much about whether I have orgasm. One more thing which seems strange no doubt. I want to please my wife, and she is much happier feeling that she gave me pleasure and release. That's right, I have sometimes faked orgasm. I've done it for real so much in my life that I can do so realistically, in a way she totally accepts. And since I ejaculate so little now and she is aware of that, there is no problem from lack of physical "evidence" should she be inclined to expect it.
Surgery at VA July 2017 after many years struggling with pills, shots, pump, etc. Should've done it way sooner! October 2020: VA just replaced the first one with another due to stuck valve...AMS 700 LGX.
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