Caverject pains?

[cotham876]

I am about to go on injections later this month. Here in UK they tend to use Caverject.
I have gleaned from a couple of people that this system is not popular in USA as it is painful. The needle I presume.
Any comment would be greatly appreciated by this cowardly Brit!

[JimStars]

Cotham,

We LAUGH at needles here ... that is not the issue with Caverject or any other shots method.

The Pfizer site says this about that ...

Penile Pain: Penile pain after intracavernosal administration of CAVERJECT was reported at least once by 37% of patients in clinical studies of up to 18 months in duration. In the majority of the cases, penile pain was rated mild or moderate in intensity.

So you have 1 in 3 chance of experiencing the Alprostadil (PGE-1) Ache. Some percentage of that 1/3 will get ache with any amount of PGE-1 and even Trimix would not be comfortable.

J

[Cajun Jeff]

I am one of the lucky guys that it does not cause me pain and it works great. The problem we have here in the US is that it is $$$$$$$$ way more expensive than TriMix. My Dr. likes the Alprostidal (Caverject) better because he said it is less likely to have to make an ER run with a 4 hr hard on.

I have used TriMix and BiMix as well. All work just as well for me.

The Pain is caused by the Drug not the needle.

Cajun Jeff

[antelope]

If I understand correctly, Caverject is the brand name for Alprostidal--one of the drugs in Trimix. Isn't that right, Jeff?

G

[cotham876]

Thanks for those posts guys. My concern was the needle not consequential pain,although that is important too.

It's mainly a psychological thing with me. Cost? luckily we don't have to worry about that too much here.

Will update later.

Cotham -

[Spartan]

If I understand correctly, Caverject is the brand name for Alprostidal--one of the drugs in Trimix. Isn't that right, Jeff?

G

Yes, you are correct, as well as the ingredient in Edex. The uniqueness of Caverject and Edex is their delivery systems, I understand. Their pricing is unconscionable. What you are paying $$$$$$$$ for is their delivery systems.

Alprostidal is a generic that is very inexpensive itself. My compounding pharmacist tells me that the cost of the materials for 4 mL of my Trimix is $8.45. That is what I am charged.

[RugbyDave]

Hi

I’m also in the UK and have been using Caverject Dual Chamber for a few months now. The pain from the needle is slight, take it steady use the points at 10-2 and you’ll be fine.

Feel free to message me if you have any questions.

Dave

[katsboytoy]

Caverject is a wasteful system and that is why my uro won't prescribe it. You mix the powder with a solution, inject, and throw the rest away. Somewhere i've read, taking the fluid out and filling single solutions for later use...Tom..

[cotham876]

Thanks guys for all the interesting replies. Seeing Consultant tomorrow. Will have more news then. In answer to your question
about cost it is free at the point of issue.

[JimStars]

Kaqts,

Caverject is a wasteful system and that is why my uro won't prescribe it. You mix the powder with a solution, inject, and throw the rest away. Somewhere i've read, taking the fluid out and filling single solutions for later use...Tom..

Yes if you get some of the cheaper/smaller capacity syringes (.3ml ... ,5ml ,, you can pull the plungers all the way out and you could then
inject into a bunch of smaller syringes from the main Caverject syringe. (just tricky putting the plungers back in -- gotta tilt so the air goes out when the plunger goes in .,. not the liquid!!).

definitely waste not want more!

J